| Trade Date | Insider | Title | Buy or Sell | Quantity | Security Type | Price | Proceeds | Transaction Conviction | Position Quantity | Position Value | Positon Conviction | SEC Link | Nature of Ownership | 2020-04-03 | Capital, Llc Armistice | - | Buy | 4,280 | Common Stock | $2.16 | -$9,244.80 | 0.59 [ Average ] | 832,194 | $1,797,539.04 | 114.30 [Very High] | Form 4 | See Footnote | 2020-04-09 | Simon Pedder | Executive Chairman of the Bd | Sell | 20,901 | Common Stock | $2.57 | $53,715.57 | 2.87 [ Very High ] | 241,833 | $621,510.81 | 33.22 [High] | Form 4 | - | 2019-06-07 | Joseph M Miller | Chief Financial Officer | Sell | 3,723 | Common Stock | $4.85 | $18,056.55 | 0.51 [ Average ] | 45,054 | $218,511.90 | 6.19 [Average] | Form 4 | - | 2019-07-16 | Pericles Calias | Chief Scientific Officer | Sell | 3,246 | Common Stock | $4.90 | $15,905.40 | 0.45 [ Average ] | 49,216 | $241,158.40 | 6.76 [Average] | Form 4 | - | 2020-06-09 | Michael F Cola | Chief Executive Officer | Buy | 100,000 | Common Stock | $2.50 | -$250,000.00 | - | 175,746 | $439,365.00 | - | Form 4 | - | 2020-06-09 | Michael F Cola | Chief Executive Officer | Buy | 100,000 | Common Stock | $2.50 | -$250,000.00 | - | 175,746 | $439,365.00 | - | Form 4 | - | 2020-06-09 | Capital, Llc Armistice | - | Buy | 1,753,680 | Common Stock | $2.50 | -$4,384,200.00 | - | 29,914,285 | $74,785,712.50 | - | Form 4 | - | 2020-06-09 | Capital, Llc Armistice | - | Buy | 0 | Common Stock | $0.00 | $0.00 | - | 29,914,285 | $0.00 | - | Form 4 | See Footnote | 2020-06-09 | Capital, Llc Armistice | - | Buy | 267,806 | Common Stock | $2.52 | -$674,871.12 | - | 1,100,000 | $2,772,000.00 | - | Form 4 | See Footnote | 2020-06-11 | Capital, Llc Armistice | - | Buy | 28,000 | Common Stock | $2.44 | -$68,320.00 | - | 1,128,000 | $2,752,320.00 | - | Form 4 | See Footnote | 2020-06-08 | Joseph M Miller | - | Sell | 4,472 | Common Stock | $3.22 | $14,399.84 | - | 40,582 | $130,674.04 | - | Form 4 | - | 2020-06-10 | Garry Arthur Neil | Chief Scientific Officer | Buy | 1,799 | Common Stock | $2.28 | -$4,101.72 | - | 74,081 | $168,904.68 | - | Form 4 | - | 2020-06-10 | Christopher Ryan Sullivan | Interim CFO | Buy | 2,954 | Common Stock | $2.28 | -$6,735.12 | - | 2,954 | $6,735.12 | - | Form 4 | - | 2020-06-09 | Harrell James Archie Jr | Chief Commercial Officer | Buy | 10,000 | Common Stock | $2.50 | -$25,000.00 | - | 21,618 | $54,045.00 | - | Form 4 | - | 2020-06-10 | Harrell James Archie Jr | Chief Commercial Officer | Buy | 6,391 | Common Stock | $2.28 | -$14,571.48 | - | 28,009 | $63,860.52 | - | Form 4 | - | 2020-09-04 | Capital, Llc Armistice | - | Buy | 100,000 | Common Stock | $2.20 | -$220,000.00 | 13.35 [ Very High ] | 30,014,285 | $66,031,427.00 | 4,007.25 [Very High] | Form 4 | - | 2020-09-04 | Capital, Llc Armistice | - | Buy | 0 | Common Stock | $0.00 | $0.00 | - | 30,014,285 | $0.00 | 4,007.25 [Very High] | Form 4 | See Footnote | 2020-11-23 | Capital, Llc Armistice | - | Buy | 37,267 | Common Stock | $2.32 | -$86,459.44 | 4.97 [ Very High ] | 30,051,552 | $69,719,600.64 | 4,011.69 [Very High] | Form 4 | - | 2020-11-23 | Capital, Llc Armistice | - | Buy | 0 | Common Stock | $0.00 | $0.00 | - | 30,051,552 | $0.00 | 4,011.69 [Very High] | Form 4 | See Footnote | 2020-11-24 | Capital, Llc Armistice | - | Buy | 47,733 | Common Stock | $2.40 | -$114,559.20 | 6.37 [ Very High ] | 30,099,285 | $72,238,284.00 | 4,018.06 [Very High] | Form 4 | - | 2020-11-24 | Capital, Llc Armistice | - | Buy | 0 | Common Stock | $0.00 | $0.00 | - | 30,099,285 | $0.00 | 4,018.06 [Very High] | Form 4 | See Footnote | 2020-11-25 | Capital, Llc Armistice | - | Buy | 15,000 | Common Stock | $2.39 | -$35,850.00 | 2.00 [ High ] | 30,114,285 | $71,973,141.15 | 4,020.06 [Very High] | Form 4 | - | 2020-11-25 | Capital, Llc Armistice | - | Buy | 0 | Common Stock | $0.00 | $0.00 | - | 30,114,285 | $0.00 | 4,020.06 [Very High] | Form 4 | See Footnote | 2020-12-03 | Capital, Llc Armistice | - | Buy | 20,000 | Common Stock | $2.44 | -$48,800.00 | 2.67 [ Very High ] | 30,134,285 | $73,527,655.40 | 4,022.73 [Very High] | Form 4 | - | 2020-12-03 | Capital, Llc Armistice | - | Buy | 0 | Common Stock | $0.00 | $0.00 | - | 30,134,285 | $0.00 | 4,022.73 [Very High] | Form 4 | See Footnote | 2020-12-10 | Garry Arthur Neil | Chief Scientific Officer | Buy | 3,599 | Common Stock | $2.28 | -$8,205.72 | 0.48 [ Average ] | 77,680 | $177,110.40 | 10.37 [Average] | Form 4 | - | 2020-12-10 | Christopher Ryan Sullivan | Interim CFO | Buy | 5,095 | Common Stock | $2.28 | -$11,616.60 | 0.68 [ Average ] | 8,049 | $18,351.72 | 1.07 [Very Low] | Form 4 | - | 2020-12-10 | Harrell James Archie Jr | Chief Commercial Officer | Buy | 171 | Common Stock | $2.28 | -$389.88 | 0.02 [ Very Low ] | 28,180 | $64,250.40 | 3.76 [Low] | Form 4 | - | 2021-01-08 | Capital, Llc Armistice | - | Buy | 2,500,000 | Common Stock | $2.60 | -$6,500,000.00 | 286.59 [ Very High ] | 32,634,285 | $84,849,141.00 | 3,741.05 [Very High] | Form 4 | - | 2021-01-08 | Capital, Llc Armistice | - | Buy | 0 | Common Stock | $0.00 | $0.00 | - | 32,634,285 | $0.00 | 3,741.05 [Very High] | Form 4 | See Footnote 1 |
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