| Trade Date | Insider | Title | Buy or Sell | Quantity | Security Type | Price | Proceeds | Transaction Conviction | Position Quantity | Position Value | Positon Conviction | SEC Link | Nature of Ownership | 2021-06-25 | Miranda Jayne Toledano | - | Buy | 1,791,549 | Common Stock, $.0001 Par Value | $0.00 | $0.00 | - | 1,791,549 | $0.00 | 349.14 [Very High] | Form 4 | - | 2021-11-04 | Advisors Llc Orbimed | - | Buy | 1,785,715 | Common Stock | $3.50 | -$6,250,002.50 | 183.32 [ Very High ] | 14,500,119 | $50,750,416.50 | 1,488.57 [Very High] | Form 4 | See Footnotes | 2021-11-04 | Advisors Llc Orbimed | - | Buy | 3,571,428 | Common Stock | $3.50 | -$12,499,998.00 | 366.64 [ Very High ] | 3,571,428 | $12,499,998.00 | 366.64 [Very High] | Form 4 | See Footnotes | 2021-11-04 | Carl L Gordon | - | Buy | 1,785,715 | Common Stock | $3.50 | -$6,250,002.50 | 183.32 [ Very High ] | 14,500,119 | $50,750,416.50 | 1,488.57 [Very High] | Form 4 | See Footnotes | 2021-11-04 | Carl L Gordon | - | Buy | 3,571,428 | Common Stock | $3.50 | -$12,499,998.00 | 366.64 [ Very High ] | 3,571,428 | $12,499,998.00 | 366.64 [Very High] | Form 4 | See Footnotes | 2021-11-16 | Vered Bisker-leib | Chief Operating Officer | Buy | 600,000 | Common Stock | $0.00 | $0.00 | - | 1,113,401 | $0.00 | 113.58 [Very High] | Form 4 | - | 2022-05-06 | Advisors Llc Orbimed | - | Buy | 10,200 | Common Stock | $1.63 | -$16,626.00 | 1.01 [ High ] | 14,510,319 | $23,651,819.97 | 1,432.37 [Very High] | Form 4 | See Footnotes | 2022-05-09 | Advisors Llc Orbimed | - | Buy | 90,712 | Common Stock | $1.56 | -$141,510.72 | 8.95 [ Very High ] | 14,601,031 | $22,777,608.36 | 1,441.32 [Very High] | Form 4 | See Footnotes | 2022-05-10 | Advisors Llc Orbimed | - | Buy | 24,447 | Common Stock | $1.60 | -$39,115.20 | 2.41 [ High ] | 14,625,478 | $23,400,764.80 | 1,443.74 [Very High] | Form 4 | See Footnotes | 2022-05-06 | Carl L Gordon | - | Buy | 10,200 | Common Stock | $1.63 | -$16,626.00 | 1.01 [ High ] | 14,510,319 | $23,651,819.97 | 1,432.37 [Very High] | Form 4 | See Footnotes | 2022-05-09 | Carl L Gordon | - | Buy | 90,712 | Common Stock | $1.56 | -$141,510.72 | 8.95 [ Very High ] | 14,601,031 | $22,777,608.36 | 1,441.32 [Very High] | Form 4 | See Footnotes | 2022-05-10 | Carl L Gordon | - | Buy | 24,447 | Common Stock | $1.60 | -$39,115.20 | 2.41 [ High ] | 14,625,478 | $23,400,764.80 | 1,443.74 [Very High] | Form 4 | See Footnotes | 2022-05-10 | Thomas J. Schuetz | CHIEF EXECUTIVE OFFICER | Buy | 27,836 | Common Stock | $1.80 | -$50,104.80 | 2.75 [ Very High ] | 5,153,303 | $9,275,945.40 | 508.70 [Very High] | Form 4 | - | 2022-05-11 | Advisors Llc Orbimed | - | Buy | 64,700 | Common Stock | $1.79 | -$115,813.00 | 6.39 [ Very High ] | 14,690,178 | $26,295,418.62 | 1,450.37 [Very High] | Form 4 | See Footnotes | 2022-05-12 | Advisors Llc Orbimed | - | Buy | 97,094 | Common Stock | $2.35 | -$228,170.90 | 9.59 [ Very High ] | 14,787,272 | $34,750,089.20 | 1,459.95 [Very High] | Form 4 | See Footnotes | 2022-05-13 | Advisors Llc Orbimed | - | Buy | 30,722 | Common Stock | $2.49 | -$76,497.78 | 3.03 [ Very High ] | 14,817,994 | $36,896,805.06 | 1,462.99 [Very High] | Form 4 | See Footnotes | 2022-05-11 | Carl L Gordon | - | Buy | 64,700 | Common Stock | $1.79 | -$115,813.00 | 6.39 [ Very High ] | 14,690,178 | $26,295,418.62 | 1,450.37 [Very High] | Form 4 | See Footnotes | 2022-05-12 | Carl L Gordon | - | Buy | 97,094 | Common Stock | $2.35 | -$228,170.90 | 9.59 [ Very High ] | 14,787,272 | $34,750,089.20 | 1,459.95 [Very High] | Form 4 | See Footnotes | 2022-05-13 | Carl L Gordon | - | Buy | 30,722 | Common Stock | $2.49 | -$76,497.78 | 3.03 [ Very High ] | 14,817,994 | $36,896,805.06 | 1,462.99 [Very High] | Form 4 | See Footnotes | 2022-05-17 | Thomas J. Schuetz | CHIEF EXECUTIVE OFFICER | Buy | 20,215 | Common Stock | $2.47 | -$49,931.05 | 2.00 [ High ] | 5,173,518 | $12,778,589.46 | 510.79 [Very High] | Form 4 | - |
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