| Trade Date | Insider | Title | Buy or Sell | Quantity | Security Type | Price | Proceeds | Transaction Conviction | Position Quantity | Position Value | Positon Conviction | SEC Link | Nature of Ownership | 2020-03-31 | Investments, Lp Rtw | - | Buy | 5,000 | Common Stock | $11.26 | -$56,300.00 | 3.35 [ Very High ] | 2,600,729 | $29,284,208.54 | 1,744.64 [Very High] | Form 4 | By RTW | 2020-04-01 | Investments, Lp Rtw | - | Buy | 26,539 | Common Stock | $10.41 | -$276,270.99 | 17.80 [ Very High ] | 2,627,268 | $27,349,859.88 | 1,762.44 [Very High] | Form 4 | By RTW | 2020-04-29 | Matthew L. Posard | - | Buy | 9,702 | Common Stock | $6.94 | -$67,331.88 | 6.51 [ Very High ] | 44,965 | $312,057.10 | 30.16 [High] | Form 4 | - | 2020-05-11 | Irwin & Joan Jacobs Trust Dated 6-2-80 | - | Buy | 41,932 | Common Stock | $9.54 | -$400,031.28 | 28.13 [ Very High ] | 1,808,434 | $17,252,460.36 | 1,213.14 [Very High] | Form 4 | - | 2020-06-17 | Scott R Pancoast | - | Buy | 8,000 | Common Stock | $0.00 | $0.00 | - | 52,514 | $0.00 | - | Form 4 | - | 2020-06-17 | Herm Rosenman | - | Buy | 8,000 | Common Stock | $0.00 | $0.00 | - | 43,224 | $0.00 | - | Form 4 | - | 2020-06-17 | Cynthia Collins | - | Buy | 8,000 | Common Stock | $0.00 | $0.00 | - | 33,483 | $0.00 | - | Form 4 | - | 2020-06-17 | Matthew L. Posard | - | Buy | 8,000 | Common Stock | $0.00 | $0.00 | - | 52,965 | $0.00 | - | Form 4 | - | 2020-06-17 | Gary E. Jacobs | - | Buy | 8,000 | Common Stock | $0.00 | $0.00 | - | 523,211 | $0.00 | - | Form 4 | - | 2020-06-17 | Enrico Picozza | - | Buy | 8,000 | Common Stock | $0.00 | $0.00 | - | 14,000 | $0.00 | - | Form 4 | - | 2020-06-25 | John Dobak | Chief Executive Officer | Buy | 60,916 | Common Stock | $0.00 | $0.00 | - | 544,939 | $0.00 | - | Form 4 | - | 2020-06-24 | Claudia Ibarra | Chief Operating Officer | Buy | 14,647 | Common Stock | $0.00 | $0.00 | - | 125,272 | $0.00 | - | Form 4 | - | 2020-06-24 | Burkhard Jansen | Chief Medical Officer | Buy | 12,872 | Common Stock | $0.00 | $0.00 | - | 84,037 | $0.00 | - | Form 4 | - | 2020-06-24 | Kevin M Sun | Chief Financial Officer | Buy | 19,947 | Common Stock | $0.00 | $0.00 | - | 151,979 | $0.00 | - | Form 4 | - | 2020-06-24 | Todd Michael Wood | Chief Commercial Officer | Buy | 15,952 | Common Stock | $0.00 | $0.00 | - | 166,972 | $0.00 | - | Form 4 | - | 2020-06-24 | Zuxu Yao | Chief Scientific Officer | Buy | 13,317 | Common Stock | $0.00 | $0.00 | - | 84,364 | $0.00 | - | Form 4 | - | 2020-08-17 | Investments, Lp Rtw | - | Buy | 31,450 | Common Stock | $9.54 | -$300,033.00 | 16.24 [ Very High ] | 2,887,216 | $27,544,040.64 | 1,490.64 [Very High] | Form 4 | By RTW | 2020-09-10 | Claudia Ibarra | Chief Operating Officer | Sell | 4,802 | Common Stock | $10.57 | $50,757.14 | 2.46 [ High ] | 120,470 | $1,273,367.90 | 61.78 [High] | Form 4 | - | 2020-09-10 | Claudia Ibarra | Chief Operating Officer | Sell | 2,803 | Common Stock | $11.25 | $31,533.75 | 1.44 [ High ] | 117,667 | $1,323,753.75 | 60.34 [High] | Form 4 | - | 2020-09-10 | John Dobak | Chief Executive Officer | Sell | 1,560 | Common Stock | $10.57 | $16,489.20 | 0.80 [ High ] | 543,379 | $5,743,516.03 | 278.64 [Very High] | Form 4 | - | 2020-09-10 | John Dobak | Chief Executive Officer | Sell | 910 | Common Stock | $11.25 | $10,237.50 | 0.47 [ Average ] | 542,469 | $6,102,776.25 | 278.17 [Very High] | Form 4 | - | 2020-09-10 | Todd Michael Wood | Chief Commercial Officer | Sell | 850 | Common Stock | $10.57 | $8,984.50 | 0.44 [ Average ] | 166,122 | $1,755,909.54 | 85.19 [Very High] | Form 4 | - | 2020-09-10 | Todd Michael Wood | Chief Commercial Officer | Sell | 495 | Common Stock | $11.25 | $5,568.75 | 0.25 [ Low ] | 165,627 | $1,863,303.75 | 84.93 [Very High] | Form 4 | - | 2020-10-26 | Gary E. Jacobs | - | Buy | 692 | Common Stock | $1.08 | -$747.36 | 0.35 [ Average ] | 523,903 | $565,815.24 | 268.65 [Very High] | Form 4 | - | 2020-12-07 | Scott R Pancoast | - | Sell | 2,382 | Common Stock | $12.00 | $28,584.00 | 1.22 [ High ] | 50,132 | $601,584.00 | 25.58 [High] | Form 4 | - | 2020-12-08 | John Dobak | Chief Executive Officer | Sell | 786 | Common Stock | $11.86 | $9,321.96 | 0.40 [ Average ] | 541,683 | $6,424,360.38 | 276.44 [Very High] | Form 4 | - | 2020-12-08 | Claudia Ibarra | Chief Operating Officer | Sell | 2,421 | Common Stock | $11.86 | $28,713.06 | 1.24 [ High ] | 115,246 | $1,366,817.56 | 58.81 [High] | Form 4 | - | 2020-12-08 | Todd Michael Wood | Chief Commercial Officer | Sell | 428 | Common Stock | $11.86 | $5,076.08 | 0.22 [ Low ] | 165,199 | $1,959,260.14 | 84.31 [High] | Form 4 | - | 2020-12-14 | Scott R Pancoast | - | Sell | 6,000 | Common Stock | $13.93 | $83,580.00 | 3.06 [ Very High ] | 44,132 | $614,758.76 | 22.52 [High] | Form 4 | - | 2020-12-14 | Burkhard Jansen | Chief Medical Officer | Sell | 5,000 | Common Stock | $12.41 | $62,050.00 | 2.55 [ High ] | 79,037 | $980,849.17 | 40.34 [High] | Form 4 | - | 2020-12-11 | Burkhard Jansen | Chief Medical Officer | Sell | 5,000 | Common Stock | $12.20 | $61,000.00 | 2.55 [ High ] | 74,037 | $903,251.40 | 37.78 [High] | Form 4 | - | 2021-01-05 | Ramin Akhavan | General Counsel | Buy | 31,250 | Common Stock | $0.00 | $0.00 | - | 31,250 | $0.00 | 15.95 [Average] | Form 4 | - | 2021-01-05 | Ramin Akhavan | General Counsel | Buy | 5,000 | Common Stock | $0.00 | $0.00 | - | 36,250 | $0.00 | 18.50 [High] | Form 4 | - | 2021-01-07 | Investments, Lp Rtw | - | Buy | 200,000 | Common Stock | $29.50 | -$5,900,000.00 | 83.92 [ Very High ] | 3,087,216 | $91,072,872.00 | 1,295.35 [Very High] | Form 4 | By RTW | 2021-01-11 | Matthew L. Posard | - | Buy | 33,898 | Common Stock | $29.50 | -$999,991.00 | 14.22 [ Very High ] | 86,863 | $2,562,458.50 | 36.45 [High] | Form 4 | - |
|---|
