| Trade Date |
Insider |
Title |
Buy or Sell |
Quantity |
Security Type |
Price |
Proceeds |
Transaction Conviction |
Position Quantity |
Position Value |
Positon Conviction |
SEC Link |
Nature of Ownership |
2020-07-02 | Amirali Talasaz | Chairman, President and COO | Buy | 54,892 | COMMON STOCK | $4.18 | -$229,448.56 | - | 2,744,424 | $11,471,692.32 | - | Form 4 | - | 2020-07-02 | Amirali Talasaz | Chairman, President and COO | Sell | 9,533 | COMMON STOCK | $83.48 | $795,814.84 | - | 2,734,891 | $228,308,700.68 | - | Form 4 | - | 2020-07-02 | Amirali Talasaz | Chairman, President and COO | Sell | 44,299 | COMMON STOCK | $83.93 | $3,718,015.07 | - | 2,690,592 | $225,821,386.56 | - | Form 4 | - | 2020-07-02 | Amirali Talasaz | Chairman, President and COO | Sell | 1,060 | COMMON STOCK | $84.81 | $89,898.60 | - | 2,689,532 | $228,099,208.92 | - | Form 4 | - | 2020-07-06 | Amirali Talasaz | Chairman, President and COO | Buy | 20,108 | COMMON STOCK | $4.18 | -$84,051.44 | - | 2,709,640 | $11,326,295.20 | - | Form 4 | - | 2020-07-06 | Amirali Talasaz | Chairman, President and COO | Sell | 15,000 | COMMON STOCK | $83.99 | $1,259,850.00 | - | 2,694,640 | $226,322,813.60 | - | Form 4 | - | 2020-07-06 | Amirali Talasaz | Chairman, President and COO | Sell | 5,108 | COMMON STOCK | $84.40 | $431,115.20 | - | 2,689,532 | $226,996,500.80 | - | Form 4 | - | 2020-04-02 | Amirali Talasaz | Chairman, President and COO | Buy | 5,250 | COMMON STOCK | $4.18 | -$21,945.00 | 0.53 [ Average ] | 76,310 | $318,975.80 | 7.77 [Average] | Form 4 | - | 2020-04-02 | Amirali Talasaz | Chairman, President and COO | Sell | 651 | COMMON STOCK | $65.63 | $42,725.13 | 0.07 [ Very Low ] | 75,659 | $4,965,500.17 | 7.70 [Average] | Form 4 | - | 2020-04-02 | Amirali Talasaz | Chairman, President and COO | Sell | 2,720 | COMMON STOCK | $66.83 | $181,777.60 | 0.28 [ Average ] | 72,939 | $4,874,513.37 | 7.42 [Average] | Form 4 | - | 2020-04-02 | Amirali Talasaz | Chairman, President and COO | Sell | 1,879 | COMMON STOCK | $67.82 | $127,433.78 | 0.19 [ Low ] | 71,060 | $4,819,289.20 | 7.23 [Average] | Form 4 | - | 2020-04-02 | Amirali Talasaz | Chairman, President and COO | Sell | 2,449 | COMMON STOCK | $65.63 | $160,727.87 | 0.25 [ Low ] | 3,196,772 | $209,804,146.36 | 325.34 [Very High] | Form 4 | Shares held by Talasaz and Eskandari 2017 Family Trust | 2020-04-02 | Amirali Talasaz | Chairman, President and COO | Sell | 10,232 | COMMON STOCK | $66.83 | $683,804.56 | 1.04 [ High ] | 3,186,540 | $212,956,468.20 | 324.30 [Very High] | Form 4 | Shares held by Talasaz and Eskandari 2017 Family Trust | 2020-04-02 | Amirali Talasaz | Chairman, President and COO | Sell | 7,069 | COMMON STOCK | $67.82 | $479,419.58 | 0.72 [ Average ] | 3,179,471 | $215,631,723.22 | 323.58 [Very High] | Form 4 | Shares held by Talasaz and Eskandari 2017 Family Trust | 2020-04-13 | Stanley J Meresman | - | Buy | 9,500 | COMMON STOCK | $5.94 | -$56,430.00 | 0.97 [ High ] | 10,802 | $64,163.88 | 1.10 [Very Low] | Form 4 | - | 2020-04-13 | Stanley J Meresman | - | Sell | 9,500 | COMMON STOCK | $66.62 | $632,890.00 | 0.97 [ High ] | 1,302 | $86,739.24 | 0.13 [Very Low] | Form 4 | - | 2020-04-14 | Ian T Clark | - | Buy | 2,689 | COMMON STOCK | $4.18 | -$11,240.02 | 0.27 [ Low ] | 3,991 | $16,682.38 | 0.41 [Very Low] | Form 4 | - | 2020-04-14 | Ian T Clark | - | Sell | 2,689 | COMMON STOCK | $70.00 | $188,230.00 | 0.27 [ Low ] | 1,302 | $91,140.00 | 0.13 [Very Low] | Form 4 | - | 2020-04-14 | Helmy Eltoukhy | Chief Executive Officer | Sell | 2,701 | COMMON STOCK | $70.06 | $189,232.06 | 0.27 [ Low ] | 3,191,084 | $223,567,345.04 | 324.76 [Very High] | Form 4 | - | 2020-04-16 | Helmy Eltoukhy | Chief Executive Officer | Sell | 200 | COMMON STOCK | $70.00 | $14,000.00 | 0.02 [ Very Low ] | 3,190,884 | $223,361,880.00 | 324.74 [Very High] | Form 4 | - | 2020-04-17 | Helmy Eltoukhy | Chief Executive Officer | Sell | 15,804 | COMMON STOCK | $70.21 | $1,109,598.84 | 1.61 [ High ] | 3,175,080 | $222,922,366.80 | 323.13 [Very High] | Form 4 | - | 2020-04-17 | Helmy Eltoukhy | Chief Executive Officer | Sell | 100 | COMMON STOCK | $71.21 | $7,121.00 | - | 3,174,980 | $226,090,325.80 | 323.12 [Very High] | Form 4 | - | 2020-04-17 | Amirali Talasaz | Chairman, President and COO | Buy | 7,771 | COMMON STOCK | $4.18 | -$32,482.78 | 0.79 [ High ] | 78,831 | $329,513.58 | 8.02 [Average] | Form 4 | - | 2020-04-17 | Amirali Talasaz | Chairman, President and COO | Sell | 6,308 | COMMON STOCK | $72.57 | $457,771.56 | 0.64 [ Average ] | 72,523 | $5,262,994.11 | 7.38 [Average] | Form 4 | - | 2020-04-17 | Amirali Talasaz | Chairman, President and COO | Sell | 1,463 | COMMON STOCK | $73.25 | $107,164.75 | 0.15 [ Low ] | 71,060 | $5,205,145.00 | 7.23 [Average] | Form 4 | - | 2020-04-17 | Amirali Talasaz | Chairman, President and COO | Sell | 23,725 | COMMON STOCK | $72.57 | $1,721,723.25 | 2.41 [ High ] | 3,155,746 | $229,012,487.22 | 321.17 [Very High] | Form 4 | Shares held by Talasaz and Eskandari 2017 Family Trust | 2020-04-17 | Amirali Talasaz | Chairman, President and COO | Sell | 5,505 | COMMON STOCK | $73.25 | $403,241.25 | 0.56 [ Average ] | 3,150,241 | $230,755,153.25 | 320.61 [Very High] | Form 4 | Shares held by Talasaz and Eskandari 2017 Family Trust | 2020-04-20 | Amirali Talasaz | Chairman, President and COO | Buy | 2,729 | COMMON STOCK | $4.18 | -$11,407.22 | 0.28 [ Average ] | 73,789 | $308,438.02 | 7.51 [Average] | Form 4 | - | 2020-04-20 | Amirali Talasaz | Chairman, President and COO | Sell | 1,994 | COMMON STOCK | $72.25 | $144,066.50 | 0.20 [ Low ] | 71,795 | $5,187,188.75 | 7.31 [Average] | Form 4 | - | 2020-04-20 | Amirali Talasaz | Chairman, President and COO | Sell | 735 | COMMON STOCK | $73.41 | $53,956.35 | 0.07 [ Very Low ] | 71,060 | $5,216,514.60 | 7.23 [Average] | Form 4 | - | 2020-04-20 | Amirali Talasaz | Chairman, President and COO | Sell | 7,505 | COMMON STOCK | $72.25 | $542,236.25 | 0.76 [ Average ] | 3,142,736 | $227,062,676.00 | 319.84 [Very High] | Form 4 | Shares held by Talasaz and Eskandari 2017 Family Trust | 2020-04-20 | Amirali Talasaz | Chairman, President and COO | Sell | 2,765 | COMMON STOCK | $73.41 | $202,978.65 | 0.28 [ Average ] | 3,139,971 | $230,505,271.11 | 319.56 [Very High] | Form 4 | Shares held by Talasaz and Eskandari 2017 Family Trust | 2020-04-23 | Michael J Wiley | Chief Legal Officer | Buy | 5,000 | COMMON STOCK | $4.18 | -$20,900.00 | 0.51 [ Average ] | 116,171 | $485,594.78 | 11.82 [Average] | Form 4 | - | 2020-04-23 | Michael J Wiley | Chief Legal Officer | Sell | 5,000 | COMMON STOCK | $77.32 | $386,600.00 | 0.51 [ Average ] | 111,171 | $8,595,741.72 | 11.31 [Average] | Form 4 | - | 2020-04-27 | Ian T Clark | - | Buy | 538 | COMMON STOCK | $4.18 | -$2,248.84 | 0.05 [ Very Low ] | 1,840 | $7,691.20 | 0.19 [Very Low] | Form 4 | - | 2020-04-27 | Ian T Clark | - | Sell | 538 | COMMON STOCK | $77.50 | $41,695.00 | 0.05 [ Very Low ] | 1,302 | $100,905.00 | 0.13 [Very Low] | Form 4 | - | 2020-04-28 | Amirali Talasaz | Chairman, President and COO | Buy | 314 | COMMON STOCK | $4.18 | -$1,312.52 | 0.03 [ Very Low ] | 3,211,345 | $13,423,422.10 | 326.82 [Very High] | Form 4 | - | 2020-04-28 | Amirali Talasaz | Chairman, President and COO | Sell | 13,082 | COMMON STOCK | $80.23 | $1,049,568.86 | 1.33 [ High ] | 3,198,263 | $256,596,640.49 | 325.49 [Very High] | Form 4 | - | 2020-04-29 | Amirali Talasaz | Chairman, President and COO | Buy | 1,040 | COMMON STOCK | $4.18 | -$4,347.20 | 0.11 [ Low ] | 3,199,303 | $13,373,086.54 | 325.60 [Very High] | Form 4 | - | 2020-04-29 | Amirali Talasaz | Chairman, President and COO | Sell | 39,872 | COMMON STOCK | $80.25 | $3,199,728.00 | 4.06 [ Very High ] | 3,159,431 | $253,544,337.75 | 321.54 [Very High] | Form 4 | - | 2020-04-29 | Amirali Talasaz | Chairman, President and COO | Sell | 3,479 | COMMON STOCK | $81.20 | $282,494.80 | 0.35 [ Average ] | 3,155,952 | $256,263,302.40 | 321.19 [Very High] | Form 4 | - | 2020-04-28 | Michael J Wiley | Chief Legal Officer | Buy | 1,220 | COMMON STOCK | $4.18 | -$5,099.60 | 0.12 [ Low ] | 112,391 | $469,794.38 | 11.44 [Average] | Form 4 | - | 2020-04-28 | Michael J Wiley | Chief Legal Officer | Sell | 1,220 | COMMON STOCK | $80.02 | $97,624.40 | 0.12 [ Low ] | 111,171 | $8,895,903.42 | 11.31 [Average] | Form 4 | - | 2020-04-29 | Michael J Wiley | Chief Legal Officer | Buy | 3,780 | COMMON STOCK | $4.18 | -$15,800.40 | 0.38 [ Average ] | 114,951 | $480,495.18 | 11.70 [Average] | Form 4 | - | 2020-04-29 | Michael J Wiley | Chief Legal Officer | Sell | 3,780 | COMMON STOCK | $80.11 | $302,815.80 | 0.38 [ Average ] | 111,171 | $8,905,908.81 | 11.31 [Average] | Form 4 | - | 2020-05-04 | Ian T Clark | - | Buy | 2,690 | COMMON STOCK | $4.18 | -$11,244.20 | 0.27 [ Average ] | 3,992 | $16,686.56 | 0.41 [Very Low] | Form 4 | - | 2020-05-04 | Ian T Clark | - | Sell | 2,690 | COMMON STOCK | $72.17 | $194,137.30 | 0.27 [ Average ] | 1,302 | $93,965.34 | 0.13 [Very Low] | Form 4 | - | 2020-05-04 | Amirali Talasaz | Chairman, President and COO | Buy | 13,435 | COMMON STOCK | $4.18 | -$56,158.30 | 1.37 [ High ] | 3,169,387 | $13,248,037.66 | 322.55 [Very High] | Form 4 | - | 2020-05-04 | Amirali Talasaz | Chairman, President and COO | Sell | 14,742 | COMMON STOCK | $72.55 | $1,069,532.10 | 1.50 [ High ] | 3,154,645 | $228,869,494.75 | 321.05 [Very High] | Form 4 | - | 2020-05-04 | Amirali Talasaz | Chairman, President and COO | Sell | 45,258 | COMMON STOCK | $73.37 | $3,320,579.46 | 4.61 [ Very High ] | 3,109,387 | $228,135,724.19 | 316.45 [Very High] | Form 4 | - | 2020-05-04 | Amirali Talasaz | Chairman, President and COO | Sell | 3,971 | COMMON STOCK | $74.00 | $293,854.00 | 0.40 [ Average ] | 3,105,416 | $229,800,784.00 | 316.04 [Very High] | Form 4 | - | 2020-05-05 | Amirali Talasaz | Chairman, President and COO | Buy | 2,800 | COMMON STOCK | $4.18 | -$11,704.00 | 0.28 [ Average ] | 3,108,216 | $12,992,342.88 | 316.33 [Very High] | Form 4 | - | 2020-05-05 | Amirali Talasaz | Chairman, President and COO | Sell | 5,970 | COMMON STOCK | $75.51 | $450,794.70 | 0.61 [ Average ] | 3,102,246 | $234,250,595.46 | 315.72 [Very High] | Form 4 | - | 2020-05-05 | Amirali Talasaz | Chairman, President and COO | Sell | 1,530 | COMMON STOCK | $76.52 | $117,075.60 | 0.16 [ Low ] | 3,100,716 | $237,266,788.32 | 315.57 [Very High] | Form 4 | - | 2020-05-05 | Amirali Talasaz | Chairman, President and COO | Sell | 2,806 | COMMON STOCK | $77.58 | $217,689.48 | 0.29 [ Average ] | 3,097,910 | $240,335,857.80 | 315.28 [Very High] | Form 4 | - | 2020-05-05 | Amirali Talasaz | Chairman, President and COO | Sell | 724 | COMMON STOCK | $78.25 | $56,653.00 | 0.07 [ Very Low ] | 3,097,186 | $242,354,804.50 | 315.21 [Very High] | Form 4 | - | 2020-05-05 | Amirali Talasaz | Chairman, President and COO | Sell | 20,153 | COMMON STOCK | $80.19 | $1,616,069.07 | 2.05 [ High ] | 3,077,033 | $246,747,276.27 | 313.16 [Very High] | Form 4 | - | 2020-05-06 | Amirali Talasaz | Chairman, President and COO | Buy | 2,400 | COMMON STOCK | $4.18 | -$10,032.00 | 0.24 [ Low ] | 3,079,433 | $12,872,029.94 | 313.40 [Very High] | Form 4 | - | 2020-05-06 | Amirali Talasaz | Chairman, President and COO | Sell | 42,402 | COMMON STOCK | $80.33 | $3,406,152.66 | 4.32 [ Very High ] | 3,037,031 | $243,964,700.23 | 309.08 [Very High] | Form 4 | - | 2020-05-06 | Amirali Talasaz | Chairman, President and COO | Sell | 22,298 | COMMON STOCK | $81.35 | $1,813,942.30 | 2.27 [ High ] | 3,014,733 | $245,248,529.55 | 306.81 [Very High] | Form 4 | - | 2020-05-06 | Amirali Talasaz | Chairman, President and COO | Sell | 35,300 | COMMON STOCK | $82.26 | $2,903,778.00 | 3.59 [ Very High ] | 2,979,433 | $245,088,158.58 | 303.22 [Very High] | Form 4 | - | 2020-05-18 | Dipchand Nishar | - | Sell | 2 | COMMON STOCK | $100.00 | $200.00 | - | 2,321 | $232,100.00 | 0.10 [Very Low] | Form 4 | - | 2020-05-22 | Derek A Bertocci | Chief Financial Officer | Buy | 7,685 | COMMON STOCK | $3.63 | -$27,896.55 | 0.78 [ High ] | 69,872 | $253,635.36 | 7.11 [Average] | Form 4 | - | 2020-05-22 | Derek A Bertocci | Chief Financial Officer | Buy | 1,537 | COMMON STOCK | $8.80 | -$13,525.60 | 0.16 [ Low ] | 71,409 | $628,399.20 | 7.27 [Average] | Form 4 | - | 2020-05-22 | Derek A Bertocci | Chief Financial Officer | Sell | 1,118 | COMMON STOCK | $95.38 | $106,634.84 | 0.11 [ Low ] | 70,291 | $6,704,355.58 | 7.15 [Average] | Form 4 | - | 2020-05-22 | Derek A Bertocci | Chief Financial Officer | Sell | 6,960 | COMMON STOCK | $96.77 | $673,519.20 | 0.71 [ Average ] | 63,331 | $6,128,540.87 | 6.45 [Average] | Form 4 | - | 2020-05-22 | Derek A Bertocci | Chief Financial Officer | Sell | 1,144 | COMMON STOCK | $97.00 | $110,968.00 | 0.12 [ Low ] | 62,187 | $6,032,139.00 | 6.33 [Average] | Form 4 | - | 2020-05-26 | Ian T Clark | - | Buy | 538 | COMMON STOCK | $4.18 | -$2,248.84 | 0.05 [ Very Low ] | 1,840 | $7,691.20 | 0.19 [Very Low] | Form 4 | - | 2020-05-26 | Ian T Clark | - | Sell | 538 | COMMON STOCK | $98.50 | $52,993.00 | 0.05 [ Very Low ] | 1,302 | $128,247.00 | 0.13 [Very Low] | Form 4 | - | 2020-05-07 | Amirali Talasaz | Chairman, President and COO | Buy | 1,762 | COMMON STOCK | $4.18 | -$7,365.16 | 0.18 [ Low ] | 2,981,195 | $12,461,395.10 | 303.40 [Very High] | Form 4 | - | 2020-05-07 | Amirali Talasaz | Chairman, President and COO | Sell | 5,400 | COMMON STOCK | $81.82 | $441,828.00 | 0.55 [ Average ] | 2,975,795 | $243,479,546.90 | 302.85 [Very High] | Form 4 | - | 2020-05-07 | Amirali Talasaz | Chairman, President and COO | Sell | 17,582 | COMMON STOCK | $82.57 | $1,451,745.74 | 1.79 [ High ] | 2,958,213 | $244,259,647.41 | 301.06 [Very High] | Form 4 | - | 2020-05-07 | Amirali Talasaz | Chairman, President and COO | Sell | 41,893 | COMMON STOCK | $83.73 | $3,507,700.89 | 4.26 [ Very High ] | 2,916,320 | $244,183,473.60 | 296.80 [Very High] | Form 4 | - | 2020-05-07 | Amirali Talasaz | Chairman, President and COO | Sell | 8,538 | COMMON STOCK | $84.27 | $719,497.26 | 0.87 [ High ] | 2,907,782 | $245,038,789.14 | 295.93 [Very High] | Form 4 | - | 2020-05-08 | Amirali Talasaz | Chairman, President and COO | Buy | 750 | COMMON STOCK | $4.18 | -$3,135.00 | 0.08 [ Very Low ] | 2,908,532 | $12,157,663.76 | 296.01 [Very High] | Form 4 | - | 2020-05-08 | Amirali Talasaz | Chairman, President and COO | Sell | 25,049 | COMMON STOCK | $90.13 | $2,257,666.37 | 2.55 [ Very High ] | 2,883,483 | $259,888,322.79 | 293.46 [Very High] | Form 4 | - | 2020-05-11 | Amirali Talasaz | Chairman, President and COO | Buy | 6,000 | COMMON STOCK | $4.18 | -$25,080.00 | 0.61 [ Average ] | 2,889,483 | $12,078,038.94 | 294.07 [Very High] | Form 4 | - | 2020-05-11 | Amirali Talasaz | Chairman, President and COO | Sell | 73,730 | COMMON STOCK | $90.40 | $6,665,192.00 | 7.50 [ Very High ] | 2,815,753 | $254,544,071.20 | 286.56 [Very High] | Form 4 | - | 2020-05-11 | Amirali Talasaz | Chairman, President and COO | Sell | 60,068 | COMMON STOCK | $91.34 | $5,486,611.12 | 6.11 [ Very High ] | 2,755,685 | $251,704,267.90 | 280.45 [Very High] | Form 4 | - | 2020-05-11 | Amirali Talasaz | Chairman, President and COO | Sell | 1,200 | COMMON STOCK | $92.00 | $110,400.00 | 0.12 [ Low ] | 2,754,485 | $253,412,620.00 | 280.33 [Very High] | Form 4 | - | 2020-05-11 | Amirali Talasaz | Chairman, President and COO | Sell | 59,953 | COMMON STOCK | $93.41 | $5,600,209.73 | 6.10 [ Very High ] | 2,694,532 | $251,696,234.12 | 274.23 [Very High] | Form 4 | - | 2020-05-11 | Amirali Talasaz | Chairman, President and COO | Sell | 5,000 | COMMON STOCK | $94.01 | $470,050.00 | 0.51 [ Average ] | 2,689,532 | $252,842,903.32 | 273.72 [Very High] | Form 4 | - | 2020-05-08 | Derek A Bertocci | Chief Financial Officer | Sell | 913 | COMMON STOCK | $90.40 | $82,535.20 | 0.09 [ Low ] | 84,049 | $7,598,029.60 | 8.55 [Average] | Form 4 | - | 2020-05-11 | Derek A Bertocci | Chief Financial Officer | Sell | 6,870 | COMMON STOCK | $90.53 | $621,941.10 | 0.70 [ Average ] | 77,179 | $6,987,014.87 | 7.85 [Average] | Form 4 | - | 2020-05-11 | Derek A Bertocci | Chief Financial Officer | Sell | 3,716 | COMMON STOCK | $91.40 | $339,642.40 | 0.38 [ Average ] | 73,463 | $6,714,518.20 | 7.48 [Average] | Form 4 | - | 2020-05-11 | Derek A Bertocci | Chief Financial Officer | Sell | 1,096 | COMMON STOCK | $92.67 | $101,566.32 | 0.11 [ Low ] | 72,367 | $6,706,249.89 | 7.36 [Average] | Form 4 | - | 2020-05-11 | Derek A Bertocci | Chief Financial Officer | Sell | 4,796 | COMMON STOCK | $93.59 | $448,857.64 | 0.49 [ Average ] | 67,571 | $6,323,969.89 | 6.88 [Average] | Form 4 | - | 2020-05-11 | Derek A Bertocci | Chief Financial Officer | Sell | 5,255 | COMMON STOCK | $94.88 | $498,594.40 | 0.53 [ Average ] | 62,316 | $5,912,542.08 | 6.34 [Average] | Form 4 | - | 2020-05-11 | Derek A Bertocci | Chief Financial Officer | Sell | 129 | COMMON STOCK | $95.31 | $12,294.99 | - | 62,187 | $5,927,042.97 | 6.33 [Average] | Form 4 | - | 2020-05-11 | Stanley J Meresman | - | Buy | 6,500 | COMMON STOCK | $5.94 | -$38,610.00 | 0.66 [ Average ] | 7,802 | $46,343.88 | 0.79 [Very Low] | Form 4 | - | 2020-05-11 | Stanley J Meresman | - | Sell | 6,500 | COMMON STOCK | $86.50 | $562,250.00 | 0.66 [ Average ] | 1,302 | $112,623.00 | 0.13 [Very Low] | Form 4 | - | 2020-07-10 | Stanley J Meresman | - | Buy | 6,000 | COMMON STOCK | $5.94 | -$35,640.00 | 0.61 [ Average ] | 10,059 | $59,750.46 | 1.02 [Very Low] | Form 4 | - | 2020-07-10 | Stanley J Meresman | - | Sell | 6,000 | COMMON STOCK | $86.66 | $519,960.00 | 0.61 [ Average ] | 4,059 | $351,752.94 | 0.41 [Very Low] | Form 4 | - | 2020-06-02 | Amirali Talasaz | Chairman, President and COO | Buy | 20,000 | COMMON STOCK | $4.18 | -$83,600.00 | - | 2,709,532 | $11,325,843.76 | - | Form 4 | - | 2020-06-02 | Amirali Talasaz | Chairman, President and COO | Sell | 10,000 | COMMON STOCK | $87.02 | $870,200.00 | - | 2,699,532 | $234,913,274.64 | - | Form 4 | - | 2020-06-02 | Amirali Talasaz | Chairman, President and COO | Sell | 10,000 | COMMON STOCK | $88.25 | $882,500.00 | - | 2,689,532 | $237,351,199.00 | - | Form 4 | - | 2020-06-03 | Amirali Talasaz | Chairman, President and COO | Buy | 55,000 | COMMON STOCK | $4.18 | -$229,900.00 | - | 2,744,532 | $11,472,143.76 | - | Form 4 | - | 2020-06-03 | Amirali Talasaz | Chairman, President and COO | Sell | 26,638 | COMMON STOCK | $85.04 | $2,265,295.52 | - | 2,717,894 | $231,129,705.76 | - | Form 4 | - | 2020-06-03 | Amirali Talasaz | Chairman, President and COO | Sell | 22,455 | COMMON STOCK | $85.92 | $1,929,333.60 | - | 2,695,439 | $231,592,118.88 | - | Form 4 | - | 2020-06-03 | Amirali Talasaz | Chairman, President and COO | Sell | 5,007 | COMMON STOCK | $87.04 | $435,809.28 | - | 2,690,432 | $234,175,201.28 | - | Form 4 | - | 2020-06-03 | Amirali Talasaz | Chairman, President and COO | Sell | 900 | COMMON STOCK | $87.66 | $78,894.00 | - | 2,689,532 | $235,764,375.12 | - | Form 4 | - | 2020-06-03 | Ian T Clark | - | Buy | 2,690 | COMMON STOCK | $4.18 | -$11,244.20 | - | 3,992 | $16,686.56 | - | Form 4 | - | 2020-06-03 | Ian T Clark | - | Sell | 2,690 | COMMON STOCK | $87.52 | $235,428.80 | - | 1,302 | $113,951.04 | - | Form 4 | - | 2020-06-04 | Svf Bluebird (cayman) Ltd | - | Sell | 7,750,000 | Common Stock | $83.16 | $644,490,000.00 | - | 15,200,460 | $1,264,070,253.60 | - | Form 4 | - | 2020-06-08 | Svf Bluebird (cayman) Ltd | - | Sell | 1,162,500 | Common Stock | $83.16 | $96,673,500.00 | - | 14,037,960 | $1,167,396,753.60 | - | Form 4 | - | 2020-06-10 | Stanley J Meresman | - | Buy | 6,000 | COMMON STOCK | $5.94 | -$35,640.00 | - | 7,302 | $43,373.88 | - | Form 4 | - | 2020-06-10 | Stanley J Meresman | - | Sell | 6,000 | COMMON STOCK | $80.59 | $483,540.00 | - | 1,302 | $104,928.18 | - | Form 4 | - | 2020-06-12 | Bahija Jallal | - | Buy | 2,757 | COMMON STOCK | $0.00 | $0.00 | - | 5,594 | $0.00 | - | Form 4 | - | 2020-06-12 | Vijaya Gadde | - | Buy | 4,703 | COMMON STOCK | $0.00 | $0.00 | - | 4,703 | $0.00 | - | Form 4 | - | 2020-06-12 | Samir Kaul | - | Buy | 2,757 | COMMON STOCK | $0.00 | $0.00 | - | 4,059 | $0.00 | 0.41 [Very Low] | Form 4 | - | 2020-05-21 | Samir Kaul | - | Sell | 6,000 | COMMON STOCK | $0.00 | $0.00 | - | 81,943 | $0.00 | 8.34 [Average] | Form 4 | By Trust | 2020-06-12 | Ian T Clark | - | Buy | 3,341 | COMMON STOCK | $0.00 | $0.00 | - | 4,643 | $0.00 | 0.47 [Very Low] | Form 4 | - | 2020-06-12 | Stanley J Meresman | - | Buy | 2,757 | COMMON STOCK | $0.00 | $0.00 | - | 4,059 | $0.00 | 0.41 [Very Low] | Form 4 | - | 2020-07-22 | John G. Saia | See Remarks | Buy | 12,412 | COMMON STOCK | $0.00 | $0.00 | - | 12,412 | $0.00 | 1.26 [Very Low] | Form 4 | - | 2020-08-01 | Derek A Bertocci | Chief Financial Officer | Sell | 714 | COMMON STOCK | $85.18 | $60,818.52 | 0.07 [ Very Low ] | 61,473 | $5,236,270.14 | 6.26 [Average] | Form 4 | - | 2020-08-03 | Amirali Talasaz | Chairman, President and COO | Buy | 60,000 | COMMON STOCK | $4.18 | -$250,800.00 | 6.11 [ Very High ] | 2,749,532 | $11,493,043.76 | 279.82 [Very High] | Form 4 | - | 2020-08-03 | Amirali Talasaz | Chairman, President and COO | Sell | 4,897 | COMMON STOCK | $85.27 | $417,567.19 | 0.50 [ Average ] | 2,744,635 | $234,035,026.45 | 279.33 [Very High] | Form 4 | - | 2020-08-03 | Amirali Talasaz | Chairman, President and COO | Sell | 43,164 | COMMON STOCK | $86.24 | $3,722,463.36 | 4.39 [ Very High ] | 2,701,471 | $232,974,859.04 | 274.93 [Very High] | Form 4 | - | 2020-08-03 | Amirali Talasaz | Chairman, President and COO | Sell | 11,939 | COMMON STOCK | $86.76 | $1,035,827.64 | 1.22 [ High ] | 2,689,532 | $233,343,796.32 | 273.72 [Very High] | Form 4 | - | 2020-08-04 | Amirali Talasaz | Chairman, President and COO | Buy | 15,000 | COMMON STOCK | $4.18 | -$62,700.00 | 1.53 [ High ] | 2,704,532 | $11,304,943.76 | 275.25 [Very High] | Form 4 | - | 2020-08-04 | Amirali Talasaz | Chairman, President and COO | Sell | 10,190 | COMMON STOCK | $83.89 | $854,839.10 | 1.04 [ High ] | 2,694,342 | $226,028,350.38 | 274.21 [Very High] | Form 4 | - | 2020-08-04 | Amirali Talasaz | Chairman, President and COO | Sell | 3,800 | COMMON STOCK | $84.51 | $321,138.00 | 0.39 [ Average ] | 2,690,542 | $227,377,704.42 | 273.82 [Very High] | Form 4 | - | 2020-08-04 | Amirali Talasaz | Chairman, President and COO | Sell | 1,010 | COMMON STOCK | $85.98 | $86,839.80 | 0.10 [ Low ] | 2,689,532 | $231,245,961.36 | 273.72 [Very High] | Form 4 | - | 2020-08-10 | Stanley J Meresman | - | Buy | 5,000 | COMMON STOCK | $5.94 | -$29,700.00 | 0.50 [ Average ] | 9,059 | $53,810.46 | 0.91 [Very Low] | Form 4 | - | 2020-08-10 | Stanley J Meresman | - | Sell | 5,000 | COMMON STOCK | $87.00 | $435,000.00 | 0.50 [ Average ] | 4,059 | $353,133.00 | 0.41 [Very Low] | Form 4 | - | 2020-08-17 | Derek A Bertocci | Chief Financial Officer | Sell | 1,113 | COMMON STOCK | $85.30 | $94,938.90 | 0.11 [ Low ] | 60,360 | $5,148,708.00 | 6.07 [Average] | Form 4 | - | 2020-08-17 | Derek A Bertocci | Chief Financial Officer | Sell | 6,136 | COMMON STOCK | $86.72 | $532,113.92 | 0.62 [ Average ] | 54,224 | $4,702,305.28 | 5.45 [Average] | Form 4 | - | 2020-08-17 | Derek A Bertocci | Chief Financial Officer | Sell | 6,218 | COMMON STOCK | $87.38 | $543,328.84 | 0.63 [ Average ] | 48,006 | $4,194,764.28 | 4.83 [Average] | Form 4 | - | 2020-08-17 | Derek A Bertocci | Chief Financial Officer | Sell | 8,673 | COMMON STOCK | $88.55 | $767,994.15 | 0.87 [ High ] | 39,333 | $3,482,937.15 | 3.96 [Low] | Form 4 | - | 2020-08-17 | Derek A Bertocci | Chief Financial Officer | Sell | 2,860 | COMMON STOCK | $89.38 | $255,626.80 | 0.29 [ Average ] | 36,473 | $3,259,956.74 | 3.67 [Low] | Form 4 | - | 2020-08-17 | Samir Kaul | - | Sell | 300 | COMMON STOCK | $85.18 | $25,554.00 | 0.03 [ Very Low ] | 81,643 | $6,954,350.74 | 8.21 [Average] | Form 4 | By Trust | 2020-08-17 | Samir Kaul | - | Sell | 4,501 | COMMON STOCK | $86.82 | $390,776.82 | 0.45 [ Average ] | 77,142 | $6,697,468.44 | 7.76 [Average] | Form 4 | By Trust | 2020-08-17 | Samir Kaul | - | Sell | 2,422 | COMMON STOCK | $87.86 | $212,796.92 | 0.24 [ Low ] | 74,720 | $6,564,899.20 | 7.52 [Average] | Form 4 | By Trust | 2020-08-17 | Samir Kaul | - | Sell | 2,277 | COMMON STOCK | $88.71 | $201,992.67 | 0.23 [ Low ] | 72,443 | $6,426,418.53 | 7.29 [Average] | Form 4 | By Trust | 2020-08-17 | Samir Kaul | - | Sell | 500 | COMMON STOCK | $89.44 | $44,720.00 | 0.05 [ Very Low ] | 71,943 | $6,434,581.92 | 7.24 [Average] | Form 4 | By Trust | 2020-08-24 | Derek A Bertocci | Chief Financial Officer | Buy | 7,686 | COMMON STOCK | $3.63 | -$27,900.18 | 0.77 [ Average ] | 44,159 | $160,297.17 | 4.44 [Low] | Form 4 | - | 2020-08-24 | Derek A Bertocci | Chief Financial Officer | Buy | 2,306 | COMMON STOCK | $8.80 | -$20,292.80 | 0.23 [ Low ] | 46,465 | $408,892.00 | 4.67 [Low] | Form 4 | - | 2020-08-24 | Derek A Bertocci | Chief Financial Officer | Sell | 2,203 | COMMON STOCK | $93.04 | $204,967.12 | 0.22 [ Low ] | 44,262 | $4,118,136.48 | 4.45 [Low] | Form 4 | - | 2020-08-24 | Derek A Bertocci | Chief Financial Officer | Sell | 3,554 | COMMON STOCK | $94.34 | $335,284.36 | 0.36 [ Average ] | 40,708 | $3,840,392.72 | 4.09 [Low] | Form 4 | - | 2020-08-24 | Derek A Bertocci | Chief Financial Officer | Sell | 3,795 | COMMON STOCK | $95.02 | $360,600.90 | 0.38 [ Average ] | 36,913 | $3,507,473.26 | 3.71 [Low] | Form 4 | - | 2020-08-24 | Derek A Bertocci | Chief Financial Officer | Sell | 440 | COMMON STOCK | $96.05 | $42,262.00 | 0.04 [ Very Low ] | 36,473 | $3,503,231.65 | 3.67 [Low] | Form 4 | - | 2020-09-01 | Derek A Bertocci | Chief Financial Officer | Sell | 22,360 | COMMON STOCK | $93.64 | $2,093,790.40 | 2.25 [ High ] | 14,113 | $1,321,541.32 | 1.42 [Low] | Form 4 | - | 2020-09-01 | Derek A Bertocci | Chief Financial Officer | Sell | 4,778 | COMMON STOCK | $94.33 | $450,708.74 | 0.48 [ Average ] | 9,335 | $880,570.55 | 0.94 [Very Low] | Form 4 | - | 2020-09-01 | Derek A Bertocci | Chief Financial Officer | Sell | 2,902 | COMMON STOCK | $95.49 | $277,111.98 | 0.29 [ Low ] | 6,433 | $614,287.17 | 0.65 [Very Low] | Form 4 | - | 2020-09-01 | Derek A Bertocci | Chief Financial Officer | Sell | 60 | COMMON STOCK | $96.08 | $5,764.80 | - | 6,373 | $612,317.84 | 0.64 [Very Low] | Form 4 | - | 2020-09-02 | Amirali Talasaz | Chairman, President and COO | Sell | 8,556 | COMMON STOCK | $92.17 | $788,606.52 | 0.86 [ High ] | 2,680,976 | $247,105,557.92 | 269.65 [Very High] | Form 4 | - | 2020-09-02 | Amirali Talasaz | Chairman, President and COO | Sell | 19,477 | COMMON STOCK | $93.23 | $1,815,840.71 | 1.96 [ High ] | 2,661,499 | $248,131,551.77 | 267.69 [Very High] | Form 4 | - | 2020-09-02 | Amirali Talasaz | Chairman, President and COO | Sell | 16,967 | COMMON STOCK | $94.10 | $1,596,594.70 | 1.71 [ High ] | 2,644,532 | $248,850,461.20 | 265.99 [Very High] | Form 4 | - | 2020-09-02 | Amirali Talasaz | Chairman, President and COO | Sell | 28,267 | COMMON STOCK | $95.30 | $2,693,845.10 | 2.84 [ Very High ] | 2,616,265 | $249,330,054.50 | 263.14 [Very High] | Form 4 | - | 2020-09-02 | Amirali Talasaz | Chairman, President and COO | Sell | 1,733 | COMMON STOCK | $95.82 | $166,056.06 | 0.17 [ Low ] | 2,614,532 | $250,524,456.24 | 262.97 [Very High] | Form 4 | - | 2020-09-08 | Ian T Clark | - | Buy | 9,146 | COMMON STOCK | $4.18 | -$38,230.28 | 0.92 [ High ] | 13,789 | $57,638.02 | 1.39 [Low] | Form 4 | - | 2020-09-08 | Ian T Clark | - | Sell | 5,263 | COMMON STOCK | $88.69 | $466,775.47 | 0.53 [ Average ] | 8,526 | $756,170.94 | 0.86 [Very Low] | Form 4 | - | 2020-09-08 | Ian T Clark | - | Sell | 2,747 | COMMON STOCK | $89.78 | $246,625.66 | 0.28 [ Low ] | 5,779 | $518,838.62 | 0.58 [Very Low] | Form 4 | - | 2020-09-08 | Ian T Clark | - | Sell | 1,136 | COMMON STOCK | $90.54 | $102,853.44 | 0.11 [ Low ] | 4,643 | $420,377.22 | 0.47 [Very Low] | Form 4 | - | 2020-09-10 | Stanley J Meresman | - | Sell | 5,000 | COMMON STOCK | $94.22 | $471,100.00 | 0.50 [ Average ] | 4,059 | $382,438.98 | 0.41 [Very Low] | Form 4 | - | 2020-09-10 | Stanley J Meresman | - | Buy | 5,000 | COMMON STOCK | $5.94 | -$29,700.00 | 0.50 [ Average ] | 9,059 | $53,810.46 | 0.91 [Very Low] | Form 4 | - | 2020-09-15 | Helmy Eltoukhy | Chief Executive Officer | Buy | 22,926 | COMMON STOCK | $4.18 | -$95,830.68 | 2.31 [ High ] | 3,317,456 | $13,866,966.08 | 333.67 [Very High] | Form 4 | - | 2020-09-15 | Helmy Eltoukhy | Chief Executive Officer | Sell | 37,474 | COMMON STOCK | $102.21 | $3,830,217.54 | 3.77 [ Very High ] | 3,279,982 | $335,246,960.22 | 329.90 [Very High] | Form 4 | - | 2020-09-15 | Helmy Eltoukhy | Chief Executive Officer | Sell | 29,785 | COMMON STOCK | $103.30 | $3,076,790.50 | 3.00 [ Very High ] | 3,250,197 | $335,745,350.10 | 326.90 [Very High] | Form 4 | - | 2020-09-15 | Helmy Eltoukhy | Chief Executive Officer | Sell | 42,106 | COMMON STOCK | $104.04 | $4,380,708.24 | 4.23 [ Very High ] | 3,208,091 | $333,769,787.64 | 322.67 [Very High] | Form 4 | - | 2020-09-15 | Helmy Eltoukhy | Chief Executive Officer | Sell | 683 | COMMON STOCK | $104.79 | $71,571.57 | 0.07 [ Very Low ] | 3,207,408 | $336,104,284.32 | 322.60 [Very High] | Form 4 | - | 2020-09-16 | Helmy Eltoukhy | Chief Executive Officer | Buy | 45,523 | COMMON STOCK | $4.18 | -$190,286.14 | 4.58 [ Very High ] | 3,252,931 | $13,597,251.58 | 327.18 [Very High] | Form 4 | - | 2020-09-16 | Helmy Eltoukhy | Chief Executive Officer | Sell | 43,351 | COMMON STOCK | $103.05 | $4,467,320.55 | 4.36 [ Very High ] | 3,209,580 | $330,747,219.00 | 322.82 [Very High] | Form 4 | - | 2020-09-16 | Helmy Eltoukhy | Chief Executive Officer | Sell | 152,011 | COMMON STOCK | $104.07 | $15,819,784.77 | 15.29 [ Very High ] | 3,057,569 | $318,201,205.83 | 307.53 [Very High] | Form 4 | - | 2020-09-16 | Helmy Eltoukhy | Chief Executive Officer | Sell | 23,147 | COMMON STOCK | $104.61 | $2,421,407.67 | 2.33 [ High ] | 3,034,422 | $317,430,885.42 | 305.20 [Very High] | Form 4 | - | 2020-09-17 | Helmy Eltoukhy | Chief Executive Officer | Buy | 42,921 | COMMON STOCK | $4.18 | -$179,409.78 | 4.32 [ Very High ] | 3,077,343 | $12,863,293.74 | 309.52 [Very High] | Form 4 | - | 2020-09-17 | Helmy Eltoukhy | Chief Executive Officer | Sell | 8,570 | COMMON STOCK | $99.16 | $849,801.20 | 0.86 [ High ] | 3,068,773 | $304,299,530.68 | 308.66 [Very High] | Form 4 | - | 2020-09-17 | Helmy Eltoukhy | Chief Executive Officer | Sell | 76,084 | COMMON STOCK | $100.02 | $7,609,921.68 | 7.65 [ Very High ] | 2,992,689 | $299,328,753.78 | 301.00 [Very High] | Form 4 | - | 2020-09-17 | Helmy Eltoukhy | Chief Executive Officer | Sell | 111,591 | COMMON STOCK | $100.94 | $11,263,995.54 | 11.22 [ Very High ] | 2,881,098 | $290,818,032.12 | 289.78 [Very High] | Form 4 | - | 2020-09-17 | Helmy Eltoukhy | Chief Executive Officer | Sell | 9,728 | COMMON STOCK | $102.10 | $993,228.80 | 0.98 [ High ] | 2,871,370 | $293,166,877.00 | 288.80 [Very High] | Form 4 | - | 2020-09-17 | Helmy Eltoukhy | Chief Executive Officer | Sell | 48 | COMMON STOCK | $102.82 | $4,935.36 | - | 2,871,322 | $295,229,328.04 | 288.80 [Very High] | Form 4 | - | 2020-09-17 | Samir Kaul | - | Sell | 1,000 | COMMON STOCK | $99.23 | $99,230.00 | 0.10 [ Low ] | 70,943 | $7,039,673.89 | 7.14 [Average] | Form 4 | By Trust | 2020-09-17 | Samir Kaul | - | Sell | 3,286 | COMMON STOCK | $100.35 | $329,750.10 | 0.33 [ Average ] | 67,657 | $6,789,379.95 | 6.80 [Average] | Form 4 | By Trust | 2020-09-17 | Samir Kaul | - | Sell | 4,514 | COMMON STOCK | $101.14 | $456,545.96 | 0.45 [ Average ] | 63,143 | $6,386,283.02 | 6.35 [Average] | Form 4 | By Trust | 2020-09-17 | Samir Kaul | - | Sell | 1,200 | COMMON STOCK | $102.26 | $122,712.00 | 0.12 [ Low ] | 61,943 | $6,334,291.18 | 6.23 [Average] | Form 4 | By Trust | 2020-09-18 | Helmy Eltoukhy | Chief Executive Officer | Buy | 13,630 | COMMON STOCK | $4.18 | -$56,973.40 | 1.37 [ High ] | 2,884,952 | $12,059,099.36 | 290.17 [Very High] | Form 4 | - | 2020-09-18 | Helmy Eltoukhy | Chief Executive Officer | Sell | 12,801 | COMMON STOCK | $100.57 | $1,287,396.57 | 1.29 [ High ] | 2,872,151 | $288,852,226.07 | 288.88 [Very High] | Form 4 | - | 2020-09-18 | Helmy Eltoukhy | Chief Executive Officer | Sell | 13,834 | COMMON STOCK | $101.55 | $1,404,842.70 | 1.39 [ High ] | 2,858,317 | $290,262,091.35 | 287.49 [Very High] | Form 4 | - | 2020-09-18 | Helmy Eltoukhy | Chief Executive Officer | Sell | 17,709 | COMMON STOCK | $102.53 | $1,815,703.77 | 1.78 [ High ] | 2,840,608 | $291,247,538.24 | 285.71 [Very High] | Form 4 | - | 2020-09-18 | Helmy Eltoukhy | Chief Executive Officer | Sell | 21,078 | COMMON STOCK | $103.00 | $2,171,034.00 | 2.12 [ High ] | 2,819,530 | $290,411,590.00 | 283.59 [Very High] | Form 4 | - | 2020-09-25 | Amirali Talasaz | Chairman, President and COO | Sell | 44,120 | COMMON STOCK | $110.44 | $4,872,612.80 | 4.44 [ Very High ] | 2,570,412 | $283,876,301.28 | 258.53 [Very High] | Form 4 | - | 2020-09-25 | Amirali Talasaz | Chairman, President and COO | Sell | 30,880 | COMMON STOCK | $111.09 | $3,430,459.20 | 3.11 [ Very High ] | 2,539,532 | $282,116,609.88 | 255.42 [Very High] | Form 4 | - | 2020-09-25 | Ian T Clark | - | Buy | 538 | COMMON STOCK | $4.18 | -$2,248.84 | 0.05 [ Very Low ] | 5,181 | $21,656.58 | 0.52 [Very Low] | Form 4 | - | 2020-09-25 | Ian T Clark | - | Sell | 538 | COMMON STOCK | $106.24 | $57,157.12 | 0.05 [ Very Low ] | 4,643 | $493,272.32 | 0.47 [Very Low] | Form 4 | - | 2020-10-05 | Ian T Clark | - | Buy | 2,690 | COMMON STOCK | $4.18 | -$11,244.20 | 0.27 [ Low ] | 7,333 | $30,651.94 | 0.74 [Very Low] | Form 4 | - | 2020-10-05 | Ian T Clark | - | Sell | 2,690 | COMMON STOCK | $108.50 | $291,865.00 | 0.27 [ Low ] | 4,643 | $503,765.50 | 0.47 [Very Low] | Form 4 | - | 2020-10-09 | Svf Bluebird (cayman) Ltd | - | Sell | 7,000,000 | Common Stock | $101.08 | $707,560,000.00 | 702.69 [ Very High ] | 7,037,960 | $711,396,996.80 | 706.50 [Very High] | Form 4 | See footnotes | 2020-10-12 | Stanley J Meresman | - | Buy | 5,000 | COMMON STOCK | $5.94 | -$29,700.00 | 0.50 [ Average ] | 9,059 | $53,810.46 | 0.91 [Very Low] | Form 4 | - | 2020-10-12 | Stanley J Meresman | - | Sell | 5,000 | COMMON STOCK | $109.37 | $546,850.00 | 0.50 [ Average ] | 4,059 | $443,932.83 | 0.41 [Very Low] | Form 4 | - | 2020-10-16 | Samir Kaul | - | Sell | 5,210 | COMMON STOCK | $101.29 | $527,720.90 | 0.52 [ Average ] | 56,733 | $5,746,485.57 | 5.70 [Average] | Form 4 | By Trust | 2020-10-16 | Samir Kaul | - | Sell | 3,215 | COMMON STOCK | $102.19 | $328,540.85 | 0.32 [ Average ] | 53,518 | $5,469,004.42 | 5.37 [Average] | Form 4 | By Trust | 2020-10-16 | Samir Kaul | - | Sell | 1,575 | COMMON STOCK | $103.21 | $162,555.75 | 0.16 [ Low ] | 51,943 | $5,361,037.03 | 5.21 [Average] | Form 4 | By Trust | 2020-10-16 | Amirali Talasaz | Chairman, President and COO | Sell | 10,599 | COMMON STOCK | $101.81 | $1,079,084.19 | 1.06 [ High ] | 727,201 | $74,036,333.81 | 73.00 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2020-10-16 | Amirali Talasaz | Chairman, President and COO | Sell | 11,000 | COMMON STOCK | $102.89 | $1,131,790.00 | 1.10 [ High ] | 716,201 | $73,689,920.89 | 71.90 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2020-10-16 | Amirali Talasaz | Chairman, President and COO | Sell | 1,801 | COMMON STOCK | $103.45 | $186,313.45 | 0.18 [ Low ] | 714,400 | $73,904,680.00 | 71.71 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2020-10-23 | Amirali Talasaz | Chairman, President and COO | Sell | 13,136 | COMMON STOCK | $105.15 | $1,381,250.40 | 1.32 [ High ] | 701,264 | $73,737,909.60 | 70.40 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2020-10-26 | Amirali Talasaz | Chairman, President and COO | Sell | 4,613 | COMMON STOCK | $105.02 | $484,457.26 | 0.46 [ Average ] | 696,651 | $73,162,288.02 | 69.93 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2020-10-27 | Amirali Talasaz | Chairman, President and COO | Sell | 14,238 | COMMON STOCK | $105.35 | $1,499,973.30 | 1.43 [ High ] | 682,413 | $71,892,209.55 | 68.50 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2020-10-27 | Amirali Talasaz | Chairman, President and COO | Sell | 25,263 | COMMON STOCK | $106.35 | $2,686,720.05 | 2.54 [ High ] | 657,150 | $69,887,902.50 | 65.97 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2020-10-27 | Amirali Talasaz | Chairman, President and COO | Sell | 9,678 | COMMON STOCK | $107.44 | $1,039,804.32 | 0.97 [ High ] | 647,472 | $69,564,391.68 | 65.00 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2020-10-27 | Amirali Talasaz | Chairman, President and COO | Sell | 13,272 | COMMON STOCK | $108.19 | $1,435,897.68 | 1.33 [ High ] | 634,200 | $68,614,098.00 | 63.66 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2020-10-27 | Amirali Talasaz | Chairman, President and COO | Sell | 10,000 | COMMON STOCK | $109.28 | $1,092,800.00 | 1.00 [ High ] | 624,200 | $68,212,576.00 | 62.66 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2020-10-27 | Amirali Talasaz | Chairman, President and COO | Sell | 3,400 | COMMON STOCK | $110.03 | $374,102.00 | 0.34 [ Average ] | 620,800 | $68,306,624.00 | 62.32 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2020-10-26 | Ian T Clark | - | Buy | 538 | COMMON STOCK | $4.18 | -$2,248.84 | 0.05 [ Very Low ] | 5,181 | $21,656.58 | 0.52 [Very Low] | Form 4 | - | 2020-10-26 | Ian T Clark | - | Sell | 538 | COMMON STOCK | $104.03 | $55,968.14 | 0.05 [ Very Low ] | 4,643 | $483,011.29 | 0.47 [Very Low] | Form 4 | - | 2020-11-03 | Ian T Clark | - | Buy | 2,690 | COMMON STOCK | $4.18 | -$11,244.20 | 0.27 [ Low ] | 7,333 | $30,651.94 | 0.74 [Very Low] | Form 4 | - | 2020-11-03 | Ian T Clark | - | Sell | 2,690 | COMMON STOCK | $105.28 | $283,203.20 | 0.27 [ Low ] | 4,643 | $488,815.04 | 0.47 [Very Low] | Form 4 | - | 2020-11-10 | Stanley J Meresman | - | Buy | 5,000 | COMMON STOCK | $5.94 | -$29,700.00 | 0.50 [ Average ] | 9,059 | $53,810.46 | 0.91 [Very Low] | Form 4 | - | 2020-11-10 | Stanley J Meresman | - | Sell | 5,000 | COMMON STOCK | $110.30 | $551,500.00 | 0.50 [ Average ] | 4,059 | $447,707.70 | 0.41 [Very Low] | Form 4 | - | 2020-11-25 | Ian T Clark | - | Buy | 538 | COMMON STOCK | $4.18 | -$2,248.84 | 0.05 [ Very Low ] | 5,181 | $21,656.58 | 0.52 [Very Low] | Form 4 | - | 2020-11-25 | Ian T Clark | - | Sell | 538 | COMMON STOCK | $113.28 | $60,944.64 | 0.05 [ Very Low ] | 4,643 | $525,959.04 | 0.46 [Very Low] | Form 4 | - | 2020-12-03 | Ian T Clark | - | Buy | 2,690 | COMMON STOCK | $4.18 | -$11,244.20 | 0.27 [ Low ] | 7,333 | $30,651.94 | 0.73 [Very Low] | Form 4 | - | 2020-12-03 | Ian T Clark | - | Sell | 2,690 | COMMON STOCK | $120.00 | $322,800.00 | 0.27 [ Low ] | 4,643 | $557,160.00 | 0.46 [Very Low] | Form 4 | - | 2020-12-10 | Stanley J Meresman | - | Buy | 4,954 | COMMON STOCK | $5.94 | -$29,426.76 | 0.50 [ Average ] | 9,013 | $53,537.22 | 0.90 [Very Low] | Form 4 | - | 2020-12-10 | Stanley J Meresman | - | Sell | 4,954 | COMMON STOCK | $125.44 | $621,429.76 | 0.50 [ Average ] | 4,059 | $509,160.96 | 0.41 [Very Low] | Form 4 | - | 2020-09-11 | John G. Saia | See Remarks | Buy | 3,491 | COMMON STOCK | $0.00 | $0.00 | - | 15,903 | $0.00 | 1.59 [Low] | Form 4 | - | 2020-12-16 | Helmy Eltoukhy | Chief Executive Officer | Buy | 23,923 | COMMON STOCK | $4.18 | -$99,998.14 | 2.39 [ High ] | 2,843,453 | $11,885,633.54 | 284.42 [Very High] | Form 4 | - | 2020-12-21 | Amirali Talasaz | Chairman, President and COO | Buy | 23,923 | COMMON STOCK | $4.18 | -$99,998.14 | 2.39 [ High ] | 2,563,455 | $10,715,241.90 | 256.42 [Very High] | Form 4 | - | 2020-12-28 | Ian T Clark | - | Buy | 538 | COMMON STOCK | $4.18 | -$2,248.84 | 0.05 [ Very Low ] | 5,181 | $21,656.58 | 0.52 [Very Low] | Form 4 | - | 2020-12-28 | Ian T Clark | - | Sell | 538 | COMMON STOCK | $135.00 | $72,630.00 | 0.05 [ Very Low ] | 4,643 | $626,805.00 | 0.46 [Very Low] | Form 4 | - | 2021-01-01 | Amirali Talasaz | Chairman, President and COO | Buy | 565,192 | COMMON STOCK | $0.00 | $0.00 | - | 3,128,647 | $0.00 | 312.95 [Very High] | Form 4 | - | 2021-01-01 | Helmy Eltoukhy | Chief Executive Officer | Buy | 565,192 | COMMON STOCK | $0.00 | $0.00 | - | 3,408,645 | $0.00 | 340.96 [Very High] | Form 4 | - | 2021-01-04 | Ian T Clark | - | Buy | 2,690 | COMMON STOCK | $4.18 | -$11,244.20 | 0.27 [ Low ] | 7,333 | $30,651.94 | 0.73 [Very Low] | Form 4 | - | 2021-01-04 | Ian T Clark | - | Sell | 2,690 | COMMON STOCK | $129.23 | $347,628.70 | 0.27 [ Low ] | 4,643 | $600,014.89 | 0.46 [Very Low] | Form 4 | - | 2021-01-06 | Amirali Talasaz | Chairman, President and COO | Sell | 279,127 | COMMON STOCK | $129.54 | $36,158,111.58 | 27.92 [ Very High ] | 2,849,520 | $369,126,820.80 | 285.03 [Very High] | Form 4 | - | 2021-01-06 | Helmy Eltoukhy | Chief Executive Officer | Sell | 279,127 | COMMON STOCK | $129.54 | $36,158,111.58 | 27.92 [ Very High ] | 3,129,518 | $405,397,761.72 | 313.04 [Very High] | Form 4 | - | 2021-01-11 | Stanley J Meresman | - | Buy | 4,934 | COMMON STOCK | $5.94 | -$29,307.96 | 0.49 [ Average ] | 8,993 | $53,418.42 | 0.90 [Very Low] | Form 4 | - | 2021-01-11 | Stanley J Meresman | - | Sell | 4,934 | COMMON STOCK | $142.00 | $700,628.00 | 0.49 [ Average ] | 4,059 | $576,378.00 | 0.41 [Very Low] | Form 4 | - | 2021-01-15 | Helmy Eltoukhy | Chief Executive Officer | Sell | 6,536 | COMMON STOCK | $156.09 | $1,020,204.24 | 0.65 [ Average ] | 657,484 | $102,626,677.56 | 65.77 [High] | Form 4 | Shares held by Eltoukhy Investments, L.P. | 2021-01-15 | Helmy Eltoukhy | Chief Executive Officer | Sell | 28,557 | COMMON STOCK | $157.22 | $4,489,731.54 | 2.86 [ Very High ] | 628,927 | $98,879,902.94 | 62.91 [High] | Form 4 | Shares held by Eltoukhy Investments, L.P. | 2021-01-15 | Helmy Eltoukhy | Chief Executive Officer | Sell | 38,176 | COMMON STOCK | $158.04 | $6,033,335.04 | 3.82 [ Very High ] | 590,751 | $93,362,288.04 | 59.09 [High] | Form 4 | Shares held by Eltoukhy Investments, L.P. | 2021-01-15 | Helmy Eltoukhy | Chief Executive Officer | Sell | 74,675 | COMMON STOCK | $159.17 | $11,886,019.75 | 7.47 [ Very High ] | 516,076 | $82,143,816.92 | 51.62 [High] | Form 4 | Shares held by Eltoukhy Investments, L.P. | 2021-01-15 | Helmy Eltoukhy | Chief Executive Officer | Sell | 1,356 | COMMON STOCK | $160.09 | $217,082.04 | 0.14 [ Low ] | 514,720 | $82,401,524.80 | 51.49 [High] | Form 4 | Shares held by Eltoukhy Investments, L.P. | 2021-01-15 | Helmy Eltoukhy | Chief Executive Officer | Sell | 700 | COMMON STOCK | $160.83 | $112,581.00 | 0.07 [ Very Low ] | 514,020 | $82,669,836.60 | 51.42 [High] | Form 4 | Shares held by Eltoukhy Investments, L.P. | 2021-01-19 | Helmy Eltoukhy | Chief Executive Officer | Sell | 10,741 | COMMON STOCK | $158.22 | $1,699,441.02 | 1.07 [ High ] | 503,279 | $79,628,803.38 | 50.34 [High] | Form 4 | Shares held by Eltoukhy Investments, L.P. | 2021-01-19 | Helmy Eltoukhy | Chief Executive Officer | Sell | 12,506 | COMMON STOCK | $159.16 | $1,990,454.96 | 1.25 [ High ] | 490,773 | $78,111,430.68 | 49.09 [High] | Form 4 | Shares held by Eltoukhy Investments, L.P. | 2021-01-19 | Helmy Eltoukhy | Chief Executive Officer | Sell | 49,841 | COMMON STOCK | $160.02 | $7,975,556.82 | 4.99 [ Very High ] | 440,932 | $70,557,938.64 | 44.11 [High] | Form 4 | Shares held by Eltoukhy Investments, L.P. | 2021-01-19 | Helmy Eltoukhy | Chief Executive Officer | Sell | 21,344 | COMMON STOCK | $161.07 | $3,437,878.08 | 2.13 [ High ] | 419,588 | $67,583,039.16 | 41.97 [High] | Form 4 | Shares held by Eltoukhy Investments, L.P. | 2021-01-19 | Helmy Eltoukhy | Chief Executive Officer | Sell | 9,285 | COMMON STOCK | $161.95 | $1,503,705.75 | 0.93 [ High ] | 410,303 | $66,448,570.85 | 41.04 [High] | Form 4 | Shares held by Eltoukhy Investments, L.P. | 2021-01-20 | Helmy Eltoukhy | Chief Executive Officer | Sell | 6,557 | COMMON STOCK | $160.95 | $1,055,349.15 | 0.66 [ Average ] | 403,746 | $64,982,918.70 | 40.39 [High] | Form 4 | Shares held by Eltoukhy Investments, L.P. | 2021-01-20 | Helmy Eltoukhy | Chief Executive Officer | Sell | 8,755 | COMMON STOCK | $161.89 | $1,417,346.95 | 0.88 [ High ] | 394,991 | $63,945,092.99 | 39.51 [High] | Form 4 | Shares held by Eltoukhy Investments, L.P. | 2021-01-20 | Helmy Eltoukhy | Chief Executive Officer | Sell | 8,174 | COMMON STOCK | $162.95 | $1,331,953.30 | 0.82 [ Average ] | 386,817 | $63,031,830.15 | 38.69 [High] | Form 4 | Shares held by Eltoukhy Investments, L.P. | 2021-01-20 | Helmy Eltoukhy | Chief Executive Officer | Sell | 8,169 | COMMON STOCK | $163.86 | $1,338,572.34 | 0.82 [ Average ] | 378,648 | $62,045,261.28 | 37.88 [High] | Form 4 | Shares held by Eltoukhy Investments, L.P. | 2021-01-20 | Helmy Eltoukhy | Chief Executive Officer | Sell | 4,380 | COMMON STOCK | $164.58 | $720,860.40 | 0.44 [ Average ] | 374,268 | $61,597,027.44 | 37.44 [High] | Form 4 | Shares held by Eltoukhy Investments, L.P. | 2021-01-20 | Helmy Eltoukhy | Chief Executive Officer | Sell | 2,819 | COMMON STOCK | $165.82 | $467,446.58 | 0.28 [ Low ] | 371,449 | $61,593,673.18 | 37.16 [High] | Form 4 | Shares held by Eltoukhy Investments, L.P. | 2021-01-20 | Helmy Eltoukhy | Chief Executive Officer | Sell | 1,908 | COMMON STOCK | $166.87 | $318,387.96 | 0.19 [ Low ] | 369,541 | $61,665,306.67 | 36.96 [High] | Form 4 | Shares held by Eltoukhy Investments, L.P. | 2021-01-20 | Helmy Eltoukhy | Chief Executive Officer | Sell | 3,766 | COMMON STOCK | $167.81 | $631,972.46 | 0.38 [ Average ] | 365,775 | $61,380,702.75 | 36.59 [High] | Form 4 | Shares held by Eltoukhy Investments, L.P. | 2021-01-20 | Helmy Eltoukhy | Chief Executive Officer | Sell | 26,243 | COMMON STOCK | $160.96 | $4,224,073.28 | 2.63 [ Very High ] | 3,103,275 | $499,503,144.00 | 310.41 [Very High] | Form 4 | - | 2021-01-20 | Helmy Eltoukhy | Chief Executive Officer | Sell | 34,584 | COMMON STOCK | $161.89 | $5,598,803.76 | 3.46 [ Very High ] | 3,068,691 | $496,790,385.99 | 306.96 [Very High] | Form 4 | - | 2021-01-20 | Helmy Eltoukhy | Chief Executive Officer | Sell | 21,882 | COMMON STOCK | $162.90 | $3,564,577.80 | 2.19 [ High ] | 3,046,809 | $496,325,186.10 | 304.77 [Very High] | Form 4 | - | 2021-01-20 | Helmy Eltoukhy | Chief Executive Officer | Sell | 29,995 | COMMON STOCK | $163.91 | $4,916,480.45 | 3.00 [ Very High ] | 3,016,814 | $494,485,982.74 | 301.77 [Very High] | Form 4 | - | 2021-01-20 | Helmy Eltoukhy | Chief Executive Officer | Sell | 24,623 | COMMON STOCK | $164.56 | $4,051,960.88 | 2.46 [ High ] | 2,992,191 | $492,394,950.96 | 299.30 [Very High] | Form 4 | - | 2021-01-20 | Helmy Eltoukhy | Chief Executive Officer | Sell | 11,104 | COMMON STOCK | $165.82 | $1,841,265.28 | 1.11 [ High ] | 2,981,087 | $494,323,846.34 | 298.19 [Very High] | Form 4 | - | 2021-01-20 | Helmy Eltoukhy | Chief Executive Officer | Sell | 5,149 | COMMON STOCK | $166.83 | $859,007.67 | 0.52 [ Average ] | 2,975,938 | $496,475,736.54 | 297.68 [Very High] | Form 4 | - | 2021-01-20 | Helmy Eltoukhy | Chief Executive Officer | Sell | 14,083 | COMMON STOCK | $167.77 | $2,362,704.91 | 1.41 [ High ] | 2,961,855 | $496,910,413.35 | 296.27 [Very High] | Form 4 | - | 2021-01-21 | Helmy Eltoukhy | Chief Executive Officer | Sell | 3,806 | COMMON STOCK | $160.29 | $610,063.74 | 0.38 [ Average ] | 2,958,049 | $474,145,674.21 | 295.89 [Very High] | Form 4 | - | 2021-01-21 | Helmy Eltoukhy | Chief Executive Officer | Sell | 33,422 | COMMON STOCK | $161.17 | $5,386,623.74 | 3.34 [ Very High ] | 2,924,627 | $471,362,133.59 | 292.54 [Very High] | Form 4 | - | 2021-01-21 | Helmy Eltoukhy | Chief Executive Officer | Sell | 118,726 | COMMON STOCK | $162.08 | $19,243,110.08 | 11.88 [ Very High ] | 2,805,901 | $454,780,434.08 | 280.67 [Very High] | Form 4 | - | 2021-01-21 | Helmy Eltoukhy | Chief Executive Officer | Sell | 6,530 | COMMON STOCK | $162.71 | $1,062,496.30 | 0.65 [ Average ] | 2,799,371 | $455,485,655.41 | 280.02 [Very High] | Form 4 | - | 2021-01-21 | Helmy Eltoukhy | Chief Executive Officer | Sell | 10,722 | COMMON STOCK | $164.01 | $1,758,515.22 | 1.07 [ High ] | 2,788,649 | $457,366,322.49 | 278.94 [Very High] | Form 4 | - | 2021-01-22 | Helmy Eltoukhy | Chief Executive Officer | Sell | 7,642 | COMMON STOCK | $158.78 | $1,213,396.76 | 0.76 [ Average ] | 2,781,007 | $441,568,291.46 | 278.18 [Very High] | Form 4 | - | 2021-01-22 | Helmy Eltoukhy | Chief Executive Officer | Sell | 91,469 | COMMON STOCK | $159.94 | $14,629,551.86 | 9.15 [ Very High ] | 2,689,538 | $430,164,707.72 | 269.03 [Very High] | Form 4 | - | 2021-01-22 | Helmy Eltoukhy | Chief Executive Officer | Sell | 1,159 | COMMON STOCK | $160.89 | $186,471.51 | 0.12 [ Low ] | 2,688,379 | $432,533,297.31 | 268.91 [Very High] | Form 4 | - | 2021-01-22 | Helmy Eltoukhy | Chief Executive Officer | Sell | 1,156 | COMMON STOCK | $161.84 | $187,087.04 | 0.12 [ Low ] | 2,687,223 | $434,900,170.32 | 268.80 [Very High] | Form 4 | - | 2021-01-22 | Helmy Eltoukhy | Chief Executive Officer | Sell | 649 | COMMON STOCK | $162.73 | $105,611.77 | 0.06 [ Very Low ] | 2,686,574 | $437,186,187.02 | 268.73 [Very High] | Form 4 | - | 2021-01-25 | Helmy Eltoukhy | Chief Executive Officer | Sell | 700 | COMMON STOCK | $153.29 | $107,303.00 | 0.07 [ Very Low ] | 2,685,874 | $411,717,625.46 | 268.66 [Very High] | Form 4 | - | 2021-01-25 | Helmy Eltoukhy | Chief Executive Officer | Sell | 7,718 | COMMON STOCK | $154.78 | $1,194,592.04 | 0.77 [ Average ] | 2,678,156 | $414,524,985.68 | 267.89 [Very High] | Form 4 | - | 2021-01-25 | Helmy Eltoukhy | Chief Executive Officer | Sell | 13,689 | COMMON STOCK | $155.55 | $2,129,323.95 | 1.37 [ High ] | 2,664,467 | $414,457,841.85 | 266.52 [Very High] | Form 4 | - | 2021-01-25 | Helmy Eltoukhy | Chief Executive Officer | Sell | 15,887 | COMMON STOCK | $156.75 | $2,490,287.25 | 1.59 [ High ] | 2,648,580 | $415,164,915.00 | 264.93 [Very High] | Form 4 | - | 2021-01-25 | Helmy Eltoukhy | Chief Executive Officer | Sell | 4,213 | COMMON STOCK | $157.28 | $662,620.64 | 0.42 [ Average ] | 2,644,367 | $415,906,041.76 | 264.51 [Very High] | Form 4 | - | 2021-01-25 | Helmy Eltoukhy | Chief Executive Officer | Sell | 1,200 | COMMON STOCK | $158.46 | $190,152.00 | 0.12 [ Low ] | 2,643,167 | $418,836,242.82 | 264.39 [Very High] | Form 4 | - | 2021-01-25 | Helmy Eltoukhy | Chief Executive Officer | Sell | 4,575 | COMMON STOCK | $160.02 | $732,091.50 | 0.46 [ Average ] | 2,638,592 | $422,227,491.84 | 263.93 [Very High] | Form 4 | - | 2021-01-25 | Helmy Eltoukhy | Chief Executive Officer | Sell | 9,229 | COMMON STOCK | $160.70 | $1,483,100.30 | 0.92 [ High ] | 2,629,363 | $422,538,634.10 | 263.01 [Very High] | Form 4 | - | 2021-01-25 | Helmy Eltoukhy | Chief Executive Officer | Sell | 1,100 | COMMON STOCK | $161.68 | $177,848.00 | 0.11 [ Low ] | 2,628,263 | $424,937,561.84 | 262.90 [Very High] | Form 4 | - | 2021-01-25 | Helmy Eltoukhy | Chief Executive Officer | Sell | 500 | COMMON STOCK | $162.83 | $81,415.00 | 0.05 [ Very Low ] | 2,627,763 | $427,878,649.29 | 262.85 [Very High] | Form 4 | - | 2021-01-25 | Ian T Clark | - | Buy | 538 | COMMON STOCK | $4.18 | -$2,248.84 | 0.05 [ Very Low ] | 5,181 | $21,656.58 | 0.52 [Very Low] | Form 4 | - | 2021-01-25 | Ian T Clark | - | Sell | 538 | COMMON STOCK | $162.00 | $87,156.00 | 0.05 [ Very Low ] | 4,643 | $752,166.00 | 0.46 [Very Low] | Form 4 | - | 2021-02-01 | Amirali Talasaz | Chairman, President and COO | Sell | 5,333 | COMMON STOCK | $152.17 | $811,522.61 | 0.53 [ Average ] | 2,844,187 | $432,799,935.79 | 284.50 [Very High] | Form 4 | - | 2021-02-01 | Amirali Talasaz | Chairman, President and COO | Sell | 10,468 | COMMON STOCK | $153.19 | $1,603,592.92 | 1.05 [ High ] | 2,833,719 | $434,097,413.61 | 283.45 [Very High] | Form 4 | - | 2021-02-01 | Amirali Talasaz | Chairman, President and COO | Sell | 28,374 | COMMON STOCK | $153.98 | $4,369,028.52 | 2.84 [ Very High ] | 2,805,345 | $431,967,023.10 | 280.61 [Very High] | Form 4 | - | 2021-02-01 | Amirali Talasaz | Chairman, President and COO | Sell | 50,011 | COMMON STOCK | $155.10 | $7,756,706.10 | 5.00 [ Very High ] | 2,755,334 | $427,352,303.40 | 275.61 [Very High] | Form 4 | - | 2021-02-01 | Amirali Talasaz | Chairman, President and COO | Sell | 1,066 | COMMON STOCK | $155.92 | $166,210.72 | 0.11 [ Low ] | 2,754,268 | $429,445,466.56 | 275.50 [Very High] | Form 4 | - | 2021-02-01 | Amirali Talasaz | Chairman, President and COO | Sell | 492 | COMMON STOCK | $157.02 | $77,253.84 | 0.05 [ Very Low ] | 2,753,776 | $432,397,907.52 | 275.45 [Very High] | Form 4 | - | 2021-02-01 | Amirali Talasaz | Chairman, President and COO | Sell | 798 | COMMON STOCK | $152.16 | $121,423.68 | 0.08 [ Very Low ] | 620,002 | $94,339,504.32 | 62.02 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2021-02-01 | Amirali Talasaz | Chairman, President and COO | Sell | 1,503 | COMMON STOCK | $153.19 | $230,244.57 | 0.15 [ Low ] | 618,499 | $94,747,861.81 | 61.87 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2021-02-01 | Amirali Talasaz | Chairman, President and COO | Sell | 4,222 | COMMON STOCK | $153.98 | $650,103.56 | 0.42 [ Average ] | 614,277 | $94,586,372.46 | 61.44 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2021-02-01 | Amirali Talasaz | Chairman, President and COO | Sell | 7,596 | COMMON STOCK | $155.10 | $1,178,139.60 | 0.76 [ Average ] | 606,681 | $94,096,223.10 | 60.69 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2021-02-01 | Amirali Talasaz | Chairman, President and COO | Sell | 122 | COMMON STOCK | $155.87 | $19,016.14 | - | 606,559 | $94,544,351.33 | 60.67 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2021-02-01 | Amirali Talasaz | Chairman, President and COO | Sell | 28 | COMMON STOCK | $157.02 | $4,396.56 | - | 606,531 | $95,237,497.62 | 60.67 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2021-02-02 | Amirali Talasaz | Chairman, President and COO | Sell | 4,629 | COMMON STOCK | $155.88 | $721,568.52 | 0.46 [ Average ] | 2,749,147 | $428,537,034.36 | 274.99 [Very High] | Form 4 | - | 2021-02-02 | Amirali Talasaz | Chairman, President and COO | Sell | 9,619 | COMMON STOCK | $156.79 | $1,508,163.01 | 0.96 [ High ] | 2,739,528 | $429,530,595.12 | 274.03 [Very High] | Form 4 | - | 2021-02-02 | Amirali Talasaz | Chairman, President and COO | Sell | 57,542 | COMMON STOCK | $157.63 | $9,070,345.46 | 5.76 [ Very High ] | 2,681,986 | $422,761,453.18 | 268.27 [Very High] | Form 4 | - | 2021-02-02 | Amirali Talasaz | Chairman, President and COO | Sell | 43,478 | COMMON STOCK | $158.91 | $6,909,088.98 | 4.35 [ Very High ] | 2,638,508 | $419,285,306.28 | 263.92 [Very High] | Form 4 | - | 2021-02-02 | Amirali Talasaz | Chairman, President and COO | Sell | 15,625 | COMMON STOCK | $159.54 | $2,492,812.50 | 1.56 [ High ] | 2,622,883 | $418,454,753.82 | 262.36 [Very High] | Form 4 | - | 2021-02-02 | Amirali Talasaz | Chairman, President and COO | Sell | 803 | COMMON STOCK | $155.87 | $125,163.61 | 0.08 [ Very Low ] | 605,728 | $94,414,823.36 | 60.59 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2021-02-02 | Amirali Talasaz | Chairman, President and COO | Sell | 1,355 | COMMON STOCK | $156.79 | $212,450.45 | 0.14 [ Low ] | 604,373 | $94,759,642.67 | 60.45 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2021-02-02 | Amirali Talasaz | Chairman, President and COO | Sell | 8,440 | COMMON STOCK | $157.65 | $1,330,566.00 | 0.84 [ High ] | 595,933 | $93,948,837.45 | 59.61 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2021-02-02 | Amirali Talasaz | Chairman, President and COO | Sell | 6,772 | COMMON STOCK | $158.92 | $1,076,206.24 | 0.68 [ Average ] | 589,161 | $93,629,466.12 | 58.93 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2021-02-02 | Amirali Talasaz | Chairman, President and COO | Sell | 2,128 | COMMON STOCK | $159.53 | $339,479.84 | 0.21 [ Low ] | 587,033 | $93,649,374.49 | 58.72 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2020-12-02 | Amirali Talasaz | Chairman, President and COO | Sell | 92,603 | COMMON STOCK | $0.00 | $0.00 | - | 2,530,280 | $0.00 | 253.10 [Very High] | Form 4 | - | 2020-12-27 | Amirali Talasaz | Chairman, President and COO | Sell | 25,000 | COMMON STOCK | $0.00 | $0.00 | - | 2,505,280 | $0.00 | 250.60 [Very High] | Form 4 | - | 2021-02-03 | Amirali Talasaz | Chairman, President and COO | Sell | 1,712 | COMMON STOCK | $156.92 | $268,647.04 | 0.17 [ Low ] | 2,503,568 | $392,859,890.56 | 250.43 [Very High] | Form 4 | - | 2021-02-03 | Amirali Talasaz | Chairman, President and COO | Sell | 31,156 | COMMON STOCK | $157.93 | $4,920,467.08 | 3.12 [ Very High ] | 2,472,412 | $390,468,027.16 | 247.31 [Very High] | Form 4 | - | 2021-02-03 | Amirali Talasaz | Chairman, President and COO | Sell | 11,074 | COMMON STOCK | $158.75 | $1,757,997.50 | 1.11 [ High ] | 2,461,338 | $390,737,407.50 | 246.20 [Very High] | Form 4 | - | 2021-02-03 | Amirali Talasaz | Chairman, President and COO | Sell | 32,638 | COMMON STOCK | $159.54 | $5,207,066.52 | 3.26 [ Very High ] | 2,428,700 | $387,474,798.00 | 242.94 [Very High] | Form 4 | - | 2021-02-03 | Amirali Talasaz | Chairman, President and COO | Sell | 335 | COMMON STOCK | $160.55 | $53,784.25 | 0.03 [ Very Low ] | 2,428,365 | $389,874,000.75 | 242.90 [Very High] | Form 4 | - | 2021-02-03 | Amirali Talasaz | Chairman, President and COO | Sell | 246 | COMMON STOCK | $156.94 | $38,607.24 | 0.02 [ Very Low ] | 586,787 | $92,090,351.78 | 58.70 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2021-02-03 | Amirali Talasaz | Chairman, President and COO | Sell | 4,606 | COMMON STOCK | $157.93 | $727,425.58 | 0.46 [ Average ] | 582,181 | $91,943,845.33 | 58.23 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2021-02-03 | Amirali Talasaz | Chairman, President and COO | Sell | 1,657 | COMMON STOCK | $158.75 | $263,048.75 | 0.17 [ Low ] | 580,524 | $92,158,185.00 | 58.07 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2021-02-03 | Amirali Talasaz | Chairman, President and COO | Sell | 4,944 | COMMON STOCK | $159.53 | $788,716.32 | 0.49 [ Average ] | 575,580 | $91,822,277.40 | 57.57 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2021-02-03 | Amirali Talasaz | Chairman, President and COO | Sell | 9 | COMMON STOCK | $160.55 | $1,444.95 | - | 575,571 | $92,407,924.05 | 57.57 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2021-02-04 | Amirali Talasaz | Chairman, President and COO | Sell | 13,594 | COMMON STOCK | $157.76 | $2,144,589.44 | 1.36 [ High ] | 2,414,771 | $380,954,272.96 | 241.54 [Very High] | Form 4 | - | 2021-02-04 | Amirali Talasaz | Chairman, President and COO | Sell | 18,180 | COMMON STOCK | $158.76 | $2,886,256.80 | 1.82 [ High ] | 2,396,591 | $380,482,787.16 | 239.73 [Very High] | Form 4 | - | 2021-02-04 | Amirali Talasaz | Chairman, President and COO | Sell | 14,051 | COMMON STOCK | $159.58 | $2,242,258.58 | 1.41 [ High ] | 2,382,540 | $380,205,733.20 | 238.32 [Very High] | Form 4 | - | 2021-02-04 | Amirali Talasaz | Chairman, President and COO | Sell | 1,228 | COMMON STOCK | $160.12 | $196,627.36 | 0.12 [ Low ] | 2,381,312 | $381,295,677.44 | 238.20 [Very High] | Form 4 | - | 2021-02-04 | Amirali Talasaz | Chairman, President and COO | Sell | 2,016 | COMMON STOCK | $157.76 | $318,044.16 | 0.20 [ Low ] | 573,555 | $90,484,036.80 | 57.37 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2021-02-04 | Amirali Talasaz | Chairman, President and COO | Sell | 2,689 | COMMON STOCK | $158.76 | $426,905.64 | 0.27 [ Low ] | 570,866 | $90,630,686.16 | 57.10 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2021-02-04 | Amirali Talasaz | Chairman, President and COO | Sell | 2,054 | COMMON STOCK | $159.58 | $327,777.32 | 0.21 [ Low ] | 568,812 | $90,771,018.96 | 56.90 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2021-02-04 | Amirali Talasaz | Chairman, President and COO | Sell | 211 | COMMON STOCK | $160.12 | $33,785.32 | 0.02 [ Very Low ] | 568,601 | $91,044,392.12 | 56.88 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2021-02-05 | Amirali Talasaz | Chairman, President and COO | Sell | 567 | COMMON STOCK | $157.84 | $89,495.28 | 0.06 [ Very Low ] | 2,380,745 | $375,776,790.80 | 238.14 [Very High] | Form 4 | - | 2021-02-05 | Amirali Talasaz | Chairman, President and COO | Sell | 2,071 | COMMON STOCK | $159.37 | $330,055.27 | 0.21 [ Low ] | 2,378,674 | $379,089,275.38 | 237.93 [Very High] | Form 4 | - | 2021-02-05 | Amirali Talasaz | Chairman, President and COO | Sell | 30,028 | COMMON STOCK | $160.03 | $4,805,380.84 | 3.00 [ Very High ] | 2,348,646 | $375,853,819.38 | 234.93 [Very High] | Form 4 | - | 2021-02-05 | Amirali Talasaz | Chairman, President and COO | Sell | 32,240 | COMMON STOCK | $161.07 | $5,192,896.80 | 3.22 [ Very High ] | 2,316,406 | $373,103,514.42 | 231.71 [Very High] | Form 4 | - | 2021-02-05 | Amirali Talasaz | Chairman, President and COO | Sell | 126,582 | COMMON STOCK | $162.31 | $20,545,524.42 | 12.66 [ Very High ] | 2,189,824 | $355,430,333.44 | 219.04 [Very High] | Form 4 | - | 2021-02-05 | Amirali Talasaz | Chairman, President and COO | Sell | 10,373 | COMMON STOCK | $163.01 | $1,690,902.73 | 1.04 [ High ] | 2,179,451 | $355,272,307.51 | 218.01 [Very High] | Form 4 | - | 2021-02-05 | Amirali Talasaz | Chairman, President and COO | Sell | 84 | COMMON STOCK | $157.84 | $13,258.56 | - | 568,517 | $89,734,723.28 | 56.87 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2021-02-05 | Amirali Talasaz | Chairman, President and COO | Sell | 406 | COMMON STOCK | $159.25 | $64,655.50 | 0.04 [ Very Low ] | 568,111 | $90,471,676.75 | 56.83 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2021-02-05 | Amirali Talasaz | Chairman, President and COO | Sell | 4,512 | COMMON STOCK | $160.03 | $722,055.36 | 0.45 [ Average ] | 563,599 | $90,192,747.97 | 56.38 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2021-02-05 | Amirali Talasaz | Chairman, President and COO | Sell | 4,825 | COMMON STOCK | $161.07 | $777,162.75 | 0.48 [ Average ] | 558,774 | $90,001,728.18 | 55.89 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2021-02-05 | Amirali Talasaz | Chairman, President and COO | Sell | 19,096 | COMMON STOCK | $162.34 | $3,100,044.64 | 1.91 [ High ] | 539,678 | $87,611,326.52 | 53.98 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2021-02-05 | Amirali Talasaz | Chairman, President and COO | Sell | 1,161 | COMMON STOCK | $163.03 | $189,277.83 | 0.12 [ Low ] | 538,517 | $87,794,426.51 | 53.87 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2021-02-08 | Amirali Talasaz | Chairman, President and COO | Sell | 14,416 | COMMON STOCK | $161.49 | $2,328,039.84 | 1.44 [ High ] | 2,165,035 | $349,631,502.15 | 216.56 [Very High] | Form 4 | - | 2021-02-08 | Amirali Talasaz | Chairman, President and COO | Sell | 49,237 | COMMON STOCK | $162.26 | $7,989,195.62 | 4.93 [ Very High ] | 2,115,798 | $343,309,383.48 | 211.64 [Very High] | Form 4 | - | 2021-02-08 | Amirali Talasaz | Chairman, President and COO | Sell | 28,995 | COMMON STOCK | $163.03 | $4,727,054.85 | 2.90 [ Very High ] | 2,086,803 | $340,211,493.09 | 208.74 [Very High] | Form 4 | - | 2021-02-08 | Amirali Talasaz | Chairman, President and COO | Sell | 60 | COMMON STOCK | $163.99 | $9,839.40 | - | 2,086,743 | $342,204,984.57 | 208.73 [Very High] | Form 4 | - | 2021-02-08 | Amirali Talasaz | Chairman, President and COO | Sell | 2,187 | COMMON STOCK | $161.48 | $353,156.76 | 0.22 [ Low ] | 536,330 | $86,606,568.40 | 53.65 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2021-02-08 | Amirali Talasaz | Chairman, President and COO | Sell | 7,325 | COMMON STOCK | $162.26 | $1,188,554.50 | 0.73 [ Average ] | 529,005 | $85,836,351.30 | 52.92 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2021-02-08 | Amirali Talasaz | Chairman, President and COO | Sell | 4,233 | COMMON STOCK | $163.04 | $690,148.32 | 0.42 [ Average ] | 524,772 | $85,558,826.88 | 52.49 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2021-02-08 | Amirali Talasaz | Chairman, President and COO | Sell | 72 | COMMON STOCK | $163.98 | $11,806.56 | - | 524,700 | $86,040,306.00 | 52.48 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2021-02-09 | Amirali Talasaz | Chairman, President and COO | Sell | 21,385 | COMMON STOCK | $161.96 | $3,463,514.60 | 2.14 [ High ] | 2,065,358 | $334,505,381.68 | 206.59 [Very High] | Form 4 | - | 2021-02-09 | Amirali Talasaz | Chairman, President and COO | Sell | 52,325 | COMMON STOCK | $162.85 | $8,521,126.25 | 5.23 [ Very High ] | 2,013,033 | $327,822,424.05 | 201.36 [Very High] | Form 4 | - | 2021-02-09 | Amirali Talasaz | Chairman, President and COO | Sell | 27,039 | COMMON STOCK | $163.84 | $4,430,069.76 | 2.70 [ Very High ] | 1,985,994 | $325,385,256.96 | 198.66 [Very High] | Form 4 | - | 2021-02-09 | Amirali Talasaz | Chairman, President and COO | Sell | 362 | COMMON STOCK | $164.27 | $59,465.74 | 0.04 [ Very Low ] | 1,985,632 | $326,179,768.64 | 198.62 [Very High] | Form 4 | - | 2021-02-09 | Amirali Talasaz | Chairman, President and COO | Sell | 3,166 | COMMON STOCK | $161.95 | $512,733.70 | 0.32 [ Average ] | 521,534 | $84,462,431.30 | 52.17 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2021-02-09 | Amirali Talasaz | Chairman, President and COO | Sell | 7,813 | COMMON STOCK | $162.85 | $1,272,347.05 | 0.78 [ Average ] | 513,721 | $83,659,464.85 | 51.39 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2021-02-09 | Amirali Talasaz | Chairman, President and COO | Sell | 4,064 | COMMON STOCK | $163.84 | $665,845.76 | 0.41 [ Average ] | 509,657 | $83,502,202.88 | 50.98 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2021-02-09 | Amirali Talasaz | Chairman, President and COO | Sell | 26 | COMMON STOCK | $164.28 | $4,271.28 | - | 509,631 | $83,722,180.68 | 50.98 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2021-02-10 | Stanley J Meresman | - | Buy | 4,934 | COMMON STOCK | $5.94 | -$29,307.96 | 0.49 [ Average ] | 8,993 | $53,418.42 | 0.90 [Very Low] | Form 4 | - | 2021-02-10 | Stanley J Meresman | - | Sell | 4,934 | COMMON STOCK | $162.71 | $802,811.14 | 0.49 [ Average ] | 4,059 | $660,439.89 | 0.41 [Very Low] | Form 4 | - | 2021-02-10 | Amirali Talasaz | Chairman, President and COO | Sell | 4,069 | COMMON STOCK | $156.11 | $635,211.59 | 0.41 [ Average ] | 1,981,908 | $309,395,657.88 | 198.25 [Very High] | Form 4 | - | 2021-02-10 | Amirali Talasaz | Chairman, President and COO | Sell | 4,579 | COMMON STOCK | $156.77 | $717,849.83 | 0.46 [ Average ] | 1,977,329 | $309,985,867.33 | 197.79 [Very High] | Form 4 | - | 2021-02-10 | Amirali Talasaz | Chairman, President and COO | Sell | 709 | COMMON STOCK | $158.13 | $112,114.17 | 0.07 [ Very Low ] | 1,976,620 | $312,562,920.60 | 197.72 [Very High] | Form 4 | - | 2021-02-10 | Amirali Talasaz | Chairman, President and COO | Sell | 5,007 | COMMON STOCK | $158.97 | $795,962.79 | 0.50 [ Average ] | 1,971,613 | $313,427,318.61 | 197.22 [Very High] | Form 4 | - | 2021-02-10 | Amirali Talasaz | Chairman, President and COO | Sell | 4,583 | COMMON STOCK | $160.08 | $733,646.64 | 0.46 [ Average ] | 1,967,030 | $314,882,162.40 | 196.76 [Very High] | Form 4 | - | 2021-02-10 | Amirali Talasaz | Chairman, President and COO | Sell | 4,594 | COMMON STOCK | $161.06 | $739,909.64 | 0.46 [ Average ] | 1,962,436 | $316,069,942.16 | 196.30 [Very High] | Form 4 | - | 2021-02-10 | Amirali Talasaz | Chairman, President and COO | Sell | 27,471 | COMMON STOCK | $162.10 | $4,453,049.10 | 2.75 [ Very High ] | 1,934,965 | $313,657,826.50 | 193.55 [Very High] | Form 4 | - | 2021-02-10 | Amirali Talasaz | Chairman, President and COO | Sell | 2,292 | COMMON STOCK | $162.88 | $373,320.96 | 0.23 [ Low ] | 1,932,673 | $314,793,778.24 | 193.32 [Very High] | Form 4 | - | 2021-02-10 | Amirali Talasaz | Chairman, President and COO | Sell | 5,000 | COMMON STOCK | $163.98 | $819,900.00 | 0.50 [ Average ] | 1,927,673 | $316,099,818.54 | 192.82 [Very High] | Form 4 | - | 2021-02-10 | Amirali Talasaz | Chairman, President and COO | Sell | 492 | COMMON STOCK | $156.11 | $76,806.12 | 0.05 [ Very Low ] | 509,139 | $79,481,689.29 | 50.93 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2021-02-10 | Amirali Talasaz | Chairman, President and COO | Sell | 701 | COMMON STOCK | $156.80 | $109,916.80 | 0.07 [ Very Low ] | 508,438 | $79,723,078.40 | 50.86 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2021-02-10 | Amirali Talasaz | Chairman, President and COO | Sell | 141 | COMMON STOCK | $158.08 | $22,289.28 | - | 508,297 | $80,351,589.76 | 50.84 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2021-02-10 | Amirali Talasaz | Chairman, President and COO | Sell | 759 | COMMON STOCK | $158.98 | $120,665.82 | 0.08 [ Very Low ] | 507,538 | $80,688,391.24 | 50.77 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2021-02-10 | Amirali Talasaz | Chairman, President and COO | Sell | 621 | COMMON STOCK | $160.07 | $99,403.47 | 0.06 [ Very Low ] | 506,917 | $81,142,204.19 | 50.71 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2021-02-10 | Amirali Talasaz | Chairman, President and COO | Sell | 653 | COMMON STOCK | $161.02 | $105,146.06 | 0.07 [ Very Low ] | 506,264 | $81,518,629.28 | 50.64 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2021-02-10 | Amirali Talasaz | Chairman, President and COO | Sell | 4,497 | COMMON STOCK | $162.11 | $729,008.67 | 0.45 [ Average ] | 501,767 | $81,341,448.37 | 50.19 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2021-02-10 | Amirali Talasaz | Chairman, President and COO | Sell | 496 | COMMON STOCK | $163.03 | $80,862.88 | 0.05 [ Very Low ] | 501,271 | $81,722,211.13 | 50.14 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2021-02-10 | Amirali Talasaz | Chairman, President and COO | Sell | 329 | COMMON STOCK | $163.94 | $53,936.26 | 0.03 [ Very Low ] | 500,942 | $82,124,431.48 | 50.11 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2021-02-11 | Amirali Talasaz | Chairman, President and COO | Sell | 2,308 | COMMON STOCK | $162.65 | $375,396.20 | 0.23 [ Low ] | 1,925,365 | $313,160,617.25 | 192.59 [Very High] | Form 4 | - | 2021-02-11 | Amirali Talasaz | Chairman, President and COO | Sell | 1,372 | COMMON STOCK | $164.10 | $225,145.20 | 0.14 [ Low ] | 1,923,993 | $315,727,251.30 | 192.45 [Very High] | Form 4 | - | 2021-02-11 | Amirali Talasaz | Chairman, President and COO | Sell | 48,728 | COMMON STOCK | $165.55 | $8,066,920.40 | 4.87 [ Very High ] | 1,875,265 | $310,450,120.75 | 187.58 [Very High] | Form 4 | - | 2021-02-11 | Amirali Talasaz | Chairman, President and COO | Sell | 44,676 | COMMON STOCK | $166.51 | $7,439,000.76 | 4.47 [ Very High ] | 1,830,589 | $304,811,374.39 | 183.11 [Very High] | Form 4 | - | 2021-02-11 | Amirali Talasaz | Chairman, President and COO | Sell | 49,899 | COMMON STOCK | $167.47 | $8,356,585.53 | 4.99 [ Very High ] | 1,780,690 | $298,212,154.30 | 178.12 [Very High] | Form 4 | - | 2021-02-11 | Amirali Talasaz | Chairman, President and COO | Sell | 50,245 | COMMON STOCK | $168.37 | $8,459,750.65 | 5.03 [ Very High ] | 1,730,445 | $291,355,024.65 | 173.09 [Very High] | Form 4 | - | 2021-02-11 | Amirali Talasaz | Chairman, President and COO | Sell | 5,023 | COMMON STOCK | $169.03 | $849,037.69 | 0.50 [ Average ] | 1,725,422 | $291,648,080.66 | 172.59 [Very High] | Form 4 | - | 2021-02-11 | Amirali Talasaz | Chairman, President and COO | Sell | 144 | COMMON STOCK | $162.81 | $23,444.64 | - | 500,798 | $81,534,922.38 | 50.09 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2021-02-11 | Amirali Talasaz | Chairman, President and COO | Sell | 204 | COMMON STOCK | $164.10 | $33,476.40 | 0.02 [ Very Low ] | 500,594 | $82,147,475.40 | 50.07 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2021-02-11 | Amirali Talasaz | Chairman, President and COO | Sell | 7,116 | COMMON STOCK | $165.55 | $1,178,053.80 | 0.71 [ Average ] | 493,478 | $81,695,282.90 | 49.36 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2021-02-11 | Amirali Talasaz | Chairman, President and COO | Sell | 6,764 | COMMON STOCK | $166.53 | $1,126,408.92 | 0.68 [ Average ] | 486,714 | $81,052,482.42 | 48.69 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2021-02-11 | Amirali Talasaz | Chairman, President and COO | Sell | 9,301 | COMMON STOCK | $167.47 | $1,557,638.47 | 0.93 [ High ] | 477,413 | $79,952,355.11 | 47.75 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2021-02-11 | Amirali Talasaz | Chairman, President and COO | Sell | 5,632 | COMMON STOCK | $168.35 | $948,147.20 | 0.56 [ Average ] | 471,781 | $79,424,331.35 | 47.19 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2021-02-11 | Amirali Talasaz | Chairman, President and COO | Sell | 981 | COMMON STOCK | $169.12 | $165,906.72 | 0.10 [ Low ] | 470,800 | $79,621,696.00 | 47.09 [High] | Form 4 | Shares held by Talasaz Investments, L.P. | 2021-02-25 | Ian T Clark | - | Buy | 538 | COMMON STOCK | $4.18 | -$2,248.84 | 0.05 [ Very Low ] | 5,181 | $21,656.58 | 0.52 [Very Low] | Form 4 | - | 2021-02-25 | Ian T Clark | - | Sell | 538 | COMMON STOCK | $154.00 | $82,852.00 | 0.05 [ Very Low ] | 4,643 | $715,022.00 | 0.46 [Very Low] | Form 4 | - | 2021-03-10 | Stanley J Meresman | - | Buy | 4,934 | COMMON STOCK | $5.94 | -$29,307.96 | 0.49 [ Average ] | 8,993 | $53,418.42 | 0.90 [Very Low] | Form 4 | - | 2021-03-10 | Stanley J Meresman | - | Sell | 4,934 | COMMON STOCK | $137.85 | $680,151.90 | 0.49 [ Average ] | 4,059 | $559,533.15 | 0.40 [Very Low] | Form 4 | - | 2021-03-25 | Ian T Clark | - | Buy | 538 | COMMON STOCK | $4.18 | -$2,248.84 | 0.05 [ Very Low ] | 5,181 | $21,656.58 | 0.52 [Very Low] | Form 4 | - | 2021-03-25 | Ian T Clark | - | Sell | 538 | COMMON STOCK | $132.09 | $71,064.42 | 0.05 [ Very Low ] | 4,643 | $613,293.87 | 0.46 [Very Low] | Form 4 | - | 2021-04-05 | Samir Kaul | - | Sell | 400 | COMMON STOCK | $155.91 | $62,364.00 | 0.04 [ Very Low ] | 24,543 | $3,826,499.13 | 2.44 [Low] | Form 4 | By Trust | 2021-04-05 | Samir Kaul | - | Sell | 500 | COMMON STOCK | $156.95 | $78,475.00 | 0.05 [ Very Low ] | 24,043 | $3,773,548.85 | 2.39 [Low] | Form 4 | By Trust | 2021-04-05 | Samir Kaul | - | Sell | 1,100 | COMMON STOCK | $158.21 | $174,031.00 | 0.11 [ Low ] | 22,943 | $3,629,812.03 | 2.28 [Low] | Form 4 | By Trust | 2021-04-05 | Samir Kaul | - | Sell | 2,435 | COMMON STOCK | $159.18 | $387,603.30 | 0.24 [ Low ] | 20,508 | $3,264,463.44 | 2.04 [Low] | Form 4 | By Trust | 2021-04-05 | Samir Kaul | - | Sell | 565 | COMMON STOCK | $159.85 | $90,315.25 | 0.06 [ Very Low ] | 19,943 | $3,187,888.55 | 1.99 [Low] | Form 4 | By Trust | 2021-04-12 | Stanley J Meresman | - | Buy | 4,934 | COMMON STOCK | $5.94 | -$29,307.96 | 0.49 [ Average ] | 8,993 | $53,418.42 | 0.90 [Very Low] | Form 4 | - | 2021-04-12 | Stanley J Meresman | - | Sell | 1,606 | COMMON STOCK | $151.91 | $243,967.46 | 0.16 [ Low ] | 7,387 | $1,122,159.17 | 0.74 [Very Low] | Form 4 | - | 2021-04-12 | Stanley J Meresman | - | Sell | 594 | COMMON STOCK | $152.99 | $90,876.06 | 0.06 [ Very Low ] | 6,793 | $1,039,261.07 | 0.68 [Very Low] | Form 4 | - | 2021-04-12 | Stanley J Meresman | - | Sell | 1,584 | COMMON STOCK | $154.47 | $244,680.48 | 0.16 [ Low ] | 5,209 | $804,634.23 | 0.52 [Very Low] | Form 4 | - | 2021-04-12 | Stanley J Meresman | - | Sell | 940 | COMMON STOCK | $155.46 | $146,132.40 | 0.09 [ Very Low ] | 4,269 | $663,658.74 | 0.43 [Very Low] | Form 4 | - | 2021-04-12 | Stanley J Meresman | - | Sell | 210 | COMMON STOCK | $156.59 | $32,883.90 | 0.02 [ Very Low ] | 4,059 | $635,598.81 | 0.40 [Very Low] | Form 4 | - | 2021-04-12 | Helmy Eltoukhy | Chief Executive Officer | Sell | 1,553 | COMMON STOCK | $151.80 | $235,745.40 | 0.15 [ Low ] | 2,405,525 | $365,158,695.00 | 239.53 [Very High] | Form 4 | - | 2021-04-12 | Helmy Eltoukhy | Chief Executive Officer | Sell | 19,864 | COMMON STOCK | $153.25 | $3,044,158.00 | 1.98 [ High ] | 2,385,661 | $365,602,548.25 | 237.55 [Very High] | Form 4 | - | 2021-04-12 | Helmy Eltoukhy | Chief Executive Officer | Sell | 11,053 | COMMON STOCK | $153.69 | $1,698,735.57 | 1.10 [ High ] | 2,374,608 | $364,953,503.52 | 236.45 [Very High] | Form 4 | - | 2021-04-12 | Helmy Eltoukhy | Chief Executive Officer | Sell | 16,513 | COMMON STOCK | $155.25 | $2,563,643.25 | 1.64 [ High ] | 2,358,095 | $366,094,248.75 | 234.81 [Very High] | Form 4 | - | 2021-04-12 | Helmy Eltoukhy | Chief Executive Officer | Sell | 23,878 | COMMON STOCK | $155.86 | $3,721,625.08 | 2.38 [ High ] | 2,334,217 | $363,811,061.62 | 232.43 [Very High] | Form 4 | - | 2021-04-13 | Helmy Eltoukhy | Chief Executive Officer | Sell | 5,593 | COMMON STOCK | $153.78 | $860,091.54 | 0.56 [ Average ] | 2,328,624 | $358,095,798.72 | 231.87 [Very High] | Form 4 | - | 2021-04-13 | Helmy Eltoukhy | Chief Executive Officer | Sell | 4,424 | COMMON STOCK | $154.68 | $684,304.32 | 0.44 [ Average ] | 2,324,200 | $359,507,256.00 | 231.43 [Very High] | Form 4 | - | 2021-04-13 | Helmy Eltoukhy | Chief Executive Officer | Sell | 10,757 | COMMON STOCK | $155.57 | $1,673,466.49 | 1.07 [ High ] | 2,313,443 | $359,902,327.51 | 230.36 [Very High] | Form 4 | - | 2021-04-13 | Helmy Eltoukhy | Chief Executive Officer | Sell | 43,728 | COMMON STOCK | $156.93 | $6,862,235.04 | 4.35 [ Very High ] | 2,269,715 | $356,186,374.95 | 226.01 [Very High] | Form 4 | - | 2021-04-13 | Helmy Eltoukhy | Chief Executive Officer | Sell | 41,020 | COMMON STOCK | $157.39 | $6,456,137.80 | 4.08 [ Very High ] | 2,228,695 | $350,774,306.05 | 221.92 [Very High] | Form 4 | - | 2021-04-13 | Helmy Eltoukhy | Chief Executive Officer | Sell | 284 | COMMON STOCK | $158.51 | $45,016.84 | 0.03 [ Very Low ] | 2,228,411 | $353,225,427.61 | 221.89 [Very High] | Form 4 | - | 2021-04-14 | Helmy Eltoukhy | Chief Executive Officer | Sell | 6,606 | COMMON STOCK | $154.49 | $1,020,560.94 | 0.66 [ Average ] | 2,221,805 | $343,246,654.45 | 221.24 [Very High] | Form 4 | - | 2021-04-14 | Helmy Eltoukhy | Chief Executive Officer | Sell | 17,637 | COMMON STOCK | $155.46 | $2,741,848.02 | 1.76 [ High ] | 2,204,168 | $342,659,957.28 | 219.48 [Very High] | Form 4 | - | 2021-04-14 | Helmy Eltoukhy | Chief Executive Officer | Sell | 10,591 | COMMON STOCK | $156.39 | $1,656,326.49 | 1.05 [ High ] | 2,193,577 | $343,053,507.03 | 218.43 [Very High] | Form 4 | - | 2021-04-14 | Helmy Eltoukhy | Chief Executive Officer | Sell | 6,047 | COMMON STOCK | $157.28 | $951,072.16 | 0.60 [ Average ] | 2,187,530 | $344,054,718.40 | 217.82 [Very High] | Form 4 | - | 2021-04-14 | Helmy Eltoukhy | Chief Executive Officer | Sell | 20,101 | COMMON STOCK | $158.00 | $3,175,958.00 | 2.00 [ High ] | 2,167,429 | $342,453,782.00 | 215.82 [Very High] | Form 4 | - |
