| Trade Date | Insider | Title | Buy or Sell | Quantity | Security Type | Price | Proceeds | Transaction Conviction | Position Quantity | Position Value | Positon Conviction | SEC Link | Nature of Ownership | 2020-04-09 | Michael Kauffman | Chief Executive Officer | Buy | 10,000 | Common Stock | $4.75 | -$47,500.00 | 1.37 [ High ] | 565,122 | $2,684,329.50 | 77.28 [High] | Form 4 | - | 2020-04-09 | Michael Kauffman | Chief Executive Officer | Sell | 10,000 | Common Stock | $20.64 | $206,400.00 | 1.37 [ High ] | 555,122 | $11,457,718.08 | 75.92 [High] | Form 4 | - | 2020-04-08 | Michael Kauffman | Chief Executive Officer | Buy | 10,000 | Common Stock | $4.75 | -$47,500.00 | 1.37 [ High ] | 766,489 | $3,640,822.75 | 104.82 [High] | Form 4 | By Spouse | 2020-04-08 | Michael Kauffman | Chief Executive Officer | Sell | 10,000 | Common Stock | $18.61 | $186,100.00 | 1.37 [ High ] | 756,489 | $14,078,260.29 | 103.46 [High] | Form 4 | By Spouse | 2020-04-08 | Sharon Shacham | President & CSO | Buy | 10,000 | Common Stock | $4.75 | -$47,500.00 | 1.37 [ High ] | 766,489 | $3,640,822.75 | 104.82 [High] | Form 4 | - | 2020-04-08 | Sharon Shacham | President & CSO | Sell | 10,000 | Common Stock | $18.61 | $186,100.00 | 1.37 [ High ] | 756,489 | $14,078,260.29 | 103.46 [High] | Form 4 | - | 2020-04-09 | Sharon Shacham | President & CSO | Buy | 10,000 | Common Stock | $4.75 | -$47,500.00 | 1.37 [ High ] | 565,122 | $2,684,329.50 | 77.28 [High] | Form 4 | By Spouse | 2020-04-09 | Sharon Shacham | President & CSO | Sell | 10,000 | Common Stock | $20.64 | $206,400.00 | 1.37 [ High ] | 555,122 | $11,457,718.08 | 75.92 [High] | Form 4 | By Spouse | 2020-05-15 | Michael Kauffman | Chief Executive Officer | Buy | 7,500 | Common Stock | $0.03 | -$225.00 | 1.03 [ High ] | 763,989 | $22,919.67 | 104.48 [Very High] | Form 4 | By Spouse | 2020-05-15 | Michael Kauffman | Chief Executive Officer | Sell | 7,500 | Common Stock | $18.65 | $139,875.00 | 1.03 [ High ] | 756,489 | $14,108,519.85 | 103.46 [Very High] | Form 4 | By Spouse | 2020-05-18 | Michael Kauffman | Chief Executive Officer | Buy | 7,500 | Common Stock | $0.03 | -$225.00 | 1.03 [ High ] | 763,989 | $22,919.67 | 104.48 [Very High] | Form 4 | By Spouse | 2020-05-18 | Michael Kauffman | Chief Executive Officer | Sell | 7,500 | Common Stock | $20.00 | $150,000.00 | 1.03 [ High ] | 756,489 | $15,129,780.00 | 103.46 [Very High] | Form 4 | By Spouse | 2020-05-15 | Sharon Shacham | President & CSO | Buy | 7,500 | Common Stock | $0.03 | -$225.00 | 1.03 [ High ] | 763,989 | $22,919.67 | 104.48 [Very High] | Form 4 | - | 2020-05-15 | Sharon Shacham | President & CSO | Sell | 7,500 | Common Stock | $18.65 | $139,875.00 | 1.03 [ High ] | 756,489 | $14,108,519.85 | 103.46 [Very High] | Form 4 | - | 2020-05-18 | Sharon Shacham | President & CSO | Buy | 7,500 | Common Stock | $0.03 | -$225.00 | 1.03 [ High ] | 763,989 | $22,919.67 | 104.48 [Very High] | Form 4 | - | 2020-05-18 | Sharon Shacham | President & CSO | Sell | 7,500 | Common Stock | $20.00 | $150,000.00 | 1.03 [ High ] | 756,489 | $15,129,780.00 | 103.46 [Very High] | Form 4 | - | 2020-07-10 | Michael Kauffman | Chief Executive Officer | Buy | 7,500 | Common Stock | $4.75 | -$35,625.00 | 0.07 [ Very Low ] | 562,622 | $2,672,454.50 | 5.24 [Average] | Form 4 | - | 2020-07-10 | Michael Kauffman | Chief Executive Officer | Sell | 7,200 | Common Stock | $18.98 | $136,656.00 | 0.07 [ Very Low ] | 555,422 | $10,541,909.56 | 5.18 [Average] | Form 4 | - | 2020-07-10 | Michael Kauffman | Chief Executive Officer | Sell | 300 | Common Stock | $19.71 | $5,913.00 | - | 555,122 | $10,941,454.62 | 5.17 [Average] | Form 4 | - | 2020-07-09 | Michael Kauffman | Chief Executive Officer | Buy | 7,500 | Common Stock | $4.75 | -$35,625.00 | 0.07 [ Very Low ] | 763,989 | $3,628,947.75 | 7.12 [Average] | Form 4 | By Spouse | 2020-07-09 | Michael Kauffman | Chief Executive Officer | Sell | 7,500 | Common Stock | $19.53 | $146,475.00 | 0.07 [ Very Low ] | 756,489 | $14,774,230.17 | 7.05 [Average] | Form 4 | By Spouse | 2020-07-09 | Sharon Shacham | President & CSO | Buy | 7,500 | Common Stock | $4.75 | -$35,625.00 | 1.03 [ High ] | 763,989 | $3,628,947.75 | 104.48 [Very High] | Form 4 | - | 2020-07-09 | Sharon Shacham | President & CSO | Sell | 7,500 | Common Stock | $19.53 | $146,475.00 | 1.03 [ High ] | 756,489 | $14,774,230.17 | 103.46 [Very High] | Form 4 | - | 2020-07-10 | Sharon Shacham | President & CSO | Buy | 7,500 | Common Stock | $4.75 | -$35,625.00 | 1.03 [ High ] | 562,622 | $2,672,454.50 | 76.94 [High] | Form 4 | By Spouse | 2020-07-10 | Sharon Shacham | President & CSO | Sell | 7,200 | Common Stock | $18.98 | $136,656.00 | 0.98 [ High ] | 555,422 | $10,541,909.56 | 75.96 [High] | Form 4 | By Spouse | 2020-07-10 | Sharon Shacham | President & CSO | Sell | 300 | Common Stock | $19.71 | $5,913.00 | 0.04 [ Very Low ] | 555,122 | $10,941,454.62 | 75.92 [High] | Form 4 | By Spouse | 2020-05-07 | Michael Kauffman | Chief Executive Officer | Buy | 7,500 | Common Stock | $4.75 | -$35,625.00 | 1.03 [ High ] | 562,622 | $2,672,454.50 | 76.94 [Very High] | Form 4 | - | 2020-05-07 | Michael Kauffman | Chief Executive Officer | Sell | 7,500 | Common Stock | $19.63 | $147,225.00 | 1.03 [ High ] | 555,122 | $10,897,044.86 | 75.92 [High] | Form 4 | - | 2020-05-07 | Michael Kauffman | Chief Executive Officer | Buy | 7,500 | Common Stock | $4.75 | -$35,625.00 | 1.03 [ High ] | 763,989 | $3,628,947.75 | 104.48 [Very High] | Form 4 | By Spouse | 2020-05-07 | Michael Kauffman | Chief Executive Officer | Sell | 7,500 | Common Stock | $19.63 | $147,225.00 | 1.03 [ High ] | 756,489 | $14,849,879.07 | 103.46 [Very High] | Form 4 | By Spouse | 2020-05-07 | Sharon Shacham | President & CSO | Buy | 7,500 | Common Stock | $4.75 | -$35,625.00 | 1.03 [ High ] | 763,989 | $3,628,947.75 | 104.48 [Very High] | Form 4 | - | 2020-05-07 | Sharon Shacham | President & CSO | Sell | 7,500 | Common Stock | $19.63 | $147,225.00 | 1.03 [ High ] | 756,489 | $14,849,879.07 | 103.46 [Very High] | Form 4 | - | 2020-05-07 | Sharon Shacham | President & CSO | Buy | 7,500 | Common Stock | $4.75 | -$35,625.00 | 1.03 [ High ] | 562,622 | $2,672,454.50 | 76.94 [Very High] | Form 4 | By Spouse | 2020-05-07 | Sharon Shacham | President & CSO | Sell | 7,500 | Common Stock | $19.63 | $147,225.00 | 1.03 [ High ] | 555,122 | $10,897,044.86 | 75.92 [High] | Form 4 | By Spouse | 2020-05-07 | Christopher Brett Primiano | EVP, CBO, GC & Secretary | Sell | 6,714 | Common Stock | $19.62 | $131,728.68 | 0.92 [ High ] | 4,649 | $91,213.38 | 0.64 [Very Low] | Form 4 | - | 2020-05-07 | Christopher Brett Primiano | EVP, CBO, GC & Secretary | Buy | 2,946 | Common Stock | $6.54 | -$19,266.84 | 0.40 [ Average ] | 7,595 | $49,671.30 | 1.04 [Very Low] | Form 4 | - | 2020-05-07 | Christopher Brett Primiano | EVP, CBO, GC & Secretary | Sell | 2,946 | Common Stock | $20.00 | $58,920.00 | 0.40 [ Average ] | 4,649 | $92,980.00 | 0.64 [Very Low] | Form 4 | - | 2020-05-07 | Ran Frenkel | Chief Dev Operations Officer | Sell | 1,974 | Common Stock | $20.00 | $39,480.00 | 0.27 [ Average ] | 35,088 | $701,760.00 | 4.80 [Average] | Form 4 | - | 2020-06-10 | Michael Kauffman | Chief Executive Officer | Buy | 7,500 | Common Stock | $4.75 | -$35,625.00 | - | 562,622 | $2,672,454.50 | - | Form 4 | - | 2020-06-10 | Michael Kauffman | Chief Executive Officer | Sell | 7,500 | Common Stock | $18.13 | $135,975.00 | - | 555,122 | $10,064,361.86 | - | Form 4 | - | 2020-06-09 | Michael Kauffman | Chief Executive Officer | Buy | 7,500 | Common Stock | $4.75 | -$35,625.00 | - | 763,989 | $3,628,947.75 | - | Form 4 | By Spouse | 2020-06-09 | Michael Kauffman | Chief Executive Officer | Sell | 7,500 | Common Stock | $18.50 | $138,750.00 | - | 756,489 | $13,995,046.50 | - | Form 4 | By Spouse | 2020-06-09 | Sharon Shacham | President & CSO | Buy | 7,500 | Common Stock | $4.75 | -$35,625.00 | - | 763,989 | $3,628,947.75 | - | Form 4 | - | 2020-06-09 | Sharon Shacham | President & CSO | Sell | 7,500 | Common Stock | $18.50 | $138,750.00 | - | 756,489 | $13,995,046.50 | - | Form 4 | - | 2020-06-10 | Sharon Shacham | President & CSO | Buy | 7,500 | Common Stock | $4.75 | -$35,625.00 | - | 562,622 | $2,672,454.50 | - | Form 4 | By Spouse | 2020-06-10 | Sharon Shacham | President & CSO | Sell | 7,500 | Common Stock | $18.13 | $135,975.00 | - | 555,122 | $10,064,361.86 | - | Form 4 | By Spouse | 2020-06-15 | Michael Kauffman | Chief Executive Officer | Buy | 7,143 | Common Stock | $0.03 | -$214.29 | - | 763,632 | $22,908.96 | - | Form 4 | By Spouse | 2020-06-15 | Michael Kauffman | Chief Executive Officer | Sell | 7,143 | Common Stock | $16.38 | $117,002.34 | - | 756,489 | $12,391,289.82 | - | Form 4 | By Spouse | 2020-06-15 | Michael Kauffman | Chief Executive Officer | Buy | 357 | Common Stock | $0.03 | -$10.71 | - | 756,846 | $22,705.38 | - | Form 4 | By Spouse | 2020-06-15 | Michael Kauffman | Chief Executive Officer | Sell | 357 | Common Stock | $16.20 | $5,783.40 | - | 756,489 | $12,255,121.80 | - | Form 4 | By Spouse | 2020-06-15 | Sharon Shacham | President & CSO | Buy | 7,143 | Common Stock | $0.03 | -$214.29 | - | 763,632 | $22,908.96 | - | Form 4 | - | 2020-06-15 | Sharon Shacham | President & CSO | Sell | 7,143 | Common Stock | $16.38 | $117,002.34 | - | 756,489 | $12,391,289.82 | - | Form 4 | - | 2020-06-15 | Sharon Shacham | President & CSO | Buy | 357 | Common Stock | $0.03 | -$10.71 | - | 756,846 | $22,705.38 | - | Form 4 | - | 2020-06-15 | Sharon Shacham | President & CSO | Sell | 357 | Common Stock | $16.20 | $5,783.40 | - | 756,489 | $12,255,121.80 | - | Form 4 | - | 2020-06-22 | Michael Kauffman | Chief Executive Officer | Buy | 7,500 | Common Stock | $0.03 | -$225.00 | - | 763,989 | $22,919.67 | - | Form 4 | By Spouse | 2020-06-22 | Michael Kauffman | Chief Executive Officer | Sell | 7,500 | Common Stock | $20.00 | $150,000.00 | - | 756,489 | $15,129,780.00 | - | Form 4 | By Spouse | 2020-06-22 | Sharon Shacham | President & CSO | Buy | 7,500 | Common Stock | $0.03 | -$225.00 | - | 763,989 | $22,919.67 | - | Form 4 | - | 2020-06-22 | Sharon Shacham | President & CSO | Sell | 7,500 | Common Stock | $20.00 | $150,000.00 | - | 756,489 | $15,129,780.00 | - | Form 4 | - | 2020-07-15 | Michael Kauffman | Chief Executive Officer | Buy | 7,500 | Common Stock | $0.03 | -$225.00 | 1.03 [ High ] | 763,989 | $22,919.67 | 104.48 [Very High] | Form 4 | By Spouse | 2020-07-15 | Michael Kauffman | Chief Executive Officer | Sell | 7,500 | Common Stock | $19.43 | $145,725.00 | 1.03 [ High ] | 756,489 | $14,698,581.27 | 103.46 [Very High] | Form 4 | By Spouse | 2020-07-15 | Sharon Shacham | President & CSO | Buy | 7,500 | Common Stock | $0.03 | -$225.00 | 1.03 [ High ] | 763,989 | $22,919.67 | 104.48 [Very High] | Form 4 | - | 2020-07-15 | Sharon Shacham | President & CSO | Sell | 7,500 | Common Stock | $19.43 | $145,725.00 | 1.03 [ High ] | 756,489 | $14,698,581.27 | 103.46 [Very High] | Form 4 | - | 2020-08-17 | Michael Kauffman | Chief Executive Officer | Buy | 1,477 | Common Stock | $0.03 | -$44.31 | 0.20 [ Low ] | 757,966 | $22,738.98 | 103.16 [Very High] | Form 4 | By Spouse | 2020-08-17 | Michael Kauffman | Chief Executive Officer | Sell | 1,477 | Common Stock | $15.00 | $22,155.00 | 0.20 [ Low ] | 756,489 | $11,347,335.00 | 102.95 [Very High] | Form 4 | By Spouse | 2020-08-17 | Sharon Shacham | President & CSO | Buy | 1,477 | Common Stock | $0.03 | -$44.31 | 0.20 [ Low ] | 757,966 | $22,738.98 | 103.16 [Very High] | Form 4 | - | 2020-08-17 | Sharon Shacham | President & CSO | Sell | 1,477 | Common Stock | $15.00 | $22,155.00 | 0.20 [ Low ] | 756,489 | $11,347,335.00 | 102.95 [Very High] | Form 4 | - | 2020-08-26 | John Demaree | Chief Commercial Officer | Buy | 7,500 | Common Stock | $14.54 | -$109,050.00 | 1.02 [ High ] | 7,500 | $109,050.00 | 1.02 [Very Low] | Form 4 | - | 2020-09-08 | Christopher Brett Primiano | EVP, CBO, GC & Secretary | Buy | 10,054 | Common Stock | $6.54 | -$65,753.16 | 1.37 [ High ] | 14,703 | $96,157.62 | 2.00 [Low] | Form 4 | - | 2020-09-08 | Christopher Brett Primiano | EVP, CBO, GC & Secretary | Sell | 10,054 | Common Stock | $14.98 | $150,608.92 | 1.37 [ High ] | 4,649 | $69,642.02 | 0.63 [Very Low] | Form 4 | - | 2020-10-12 | Michael Kauffman | Chief Executive Officer | Buy | 1,424 | Common Stock | $0.03 | -$42.72 | 0.19 [ Low ] | 757,913 | $22,737.39 | 103.15 [Very High] | Form 4 | By Spouse | 2020-10-12 | Michael Kauffman | Chief Executive Officer | Buy | 6,076 | Common Stock | $0.03 | -$182.28 | 0.83 [ High ] | 763,989 | $22,919.67 | 103.98 [Very High] | Form 4 | By Spouse | 2020-10-12 | Michael Kauffman | Chief Executive Officer | Sell | 7,500 | Common Stock | $14.89 | $111,675.00 | 1.02 [ High ] | 756,489 | $11,264,121.21 | 102.95 [Very High] | Form 4 | By Spouse | 2020-10-12 | Sharon Shacham | President & CSO | Buy | 1,424 | Common Stock | $0.03 | -$42.72 | 0.19 [ Low ] | 757,913 | $22,737.39 | 103.15 [Very High] | Form 4 | - | 2020-10-12 | Sharon Shacham | President & CSO | Buy | 6,076 | Common Stock | $0.03 | -$182.28 | 0.83 [ High ] | 763,989 | $22,919.67 | 103.98 [Very High] | Form 4 | - | 2020-10-12 | Sharon Shacham | President & CSO | Sell | 7,500 | Common Stock | $14.89 | $111,675.00 | 1.02 [ High ] | 756,489 | $11,264,121.21 | 102.95 [Very High] | Form 4 | - | 2020-10-13 | Christopher Brett Primiano | EVP, CBO, GC & Secretary | Buy | 38,550 | Common Stock | $9.21 | -$355,045.50 | 5.25 [ Very High ] | 43,199 | $397,862.79 | 5.88 [Average] | Form 4 | - | 2020-10-13 | Christopher Brett Primiano | EVP, CBO, GC & Secretary | Sell | 38,550 | Common Stock | $16.85 | $649,567.50 | 5.25 [ Very High ] | 4,649 | $78,335.65 | 0.63 [Very Low] | Form 4 | - | 2020-10-13 | Christopher Brett Primiano | EVP, CBO, GC & Secretary | Buy | 721 | Common Stock | $10.39 | -$7,491.19 | 0.10 [ Low ] | 5,370 | $55,794.30 | 0.73 [Very Low] | Form 4 | - | 2020-10-13 | Christopher Brett Primiano | EVP, CBO, GC & Secretary | Sell | 721 | Common Stock | $17.20 | $12,401.20 | 0.10 [ Low ] | 4,649 | $79,962.80 | 0.63 [Very Low] | Form 4 | - | 2020-10-28 | Tanya Lewis | EVP,Chief Reg.&Quality Officer | Buy | 765 | Common Stock | $0.00 | $0.00 | - | 765 | $0.00 | 0.10 [Very Low] | Form 4 | - | 2020-10-30 | Tanya Lewis | EVP,Chief Reg.&Quality Officer | Sell | 226 | Common Stock | $15.58 | $3,521.08 | 0.03 [ Very Low ] | 539 | $8,397.62 | 0.07 [Very Low] | Form 4 | - | 2020-11-02 | Christopher Brett Primiano | EVP, CBO, GC & Secretary | Sell | 772 | Common Stock | $14.92 | $11,518.24 | 0.11 [ Low ] | 4,523 | $67,483.16 | 0.62 [Very Low] | Form 4 | - | 2020-07-11 | Jatin Shah | EVP, Chief Medical Officer | Buy | 2,413 | Common Stock | $0.00 | $0.00 | - | 43,172 | $0.00 | 5.88 [Average] | Form 4 | - | 2020-07-15 | Jatin Shah | EVP, Chief Medical Officer | Sell | 589 | Common Stock | $19.46 | $11,461.94 | 0.08 [ Very Low ] | 43,229 | $841,236.34 | 5.88 [Average] | Form 4 | - | 2020-12-01 | Christopher Brett Primiano | EVP, CBO, GC & Secretary | Buy | 78,124 | Common Stock | $10.45 | -$816,395.80 | 10.61 [ Very High ] | 82,647 | $863,661.15 | 11.23 [Average] | Form 4 | - | 2020-12-01 | Christopher Brett Primiano | EVP, CBO, GC & Secretary | Sell | 78,124 | Common Stock | $17.66 | $1,379,669.84 | 10.61 [ Very High ] | 4,523 | $79,876.18 | 0.61 [Very Low] | Form 4 | - | 2020-12-01 | Christopher Brett Primiano | EVP, CBO, GC & Secretary | Buy | 58,937 | Common Stock | $10.39 | -$612,355.43 | 8.01 [ Very High ] | 63,460 | $659,349.40 | 8.62 [Average] | Form 4 | - | 2020-12-01 | Christopher Brett Primiano | EVP, CBO, GC & Secretary | Sell | 58,937 | Common Stock | $17.35 | $1,022,556.95 | 8.01 [ Very High ] | 4,523 | $78,474.05 | 0.61 [Very Low] | Form 4 | - | 2020-12-07 | Mansoor Raza Mirza | - | Buy | 20,000 | Common Stock | $5.43 | -$108,600.00 | 2.72 [ Very High ] | 20,000 | $108,600.00 | 2.72 [Low] | Form 4 | - | 2020-12-07 | Mansoor Raza Mirza | - | Sell | 5,000 | Common Stock | $16.05 | $80,250.00 | 0.68 [ Average ] | 15,000 | $240,750.00 | 2.04 [Low] | Form 4 | - | 2020-12-07 | Mansoor Raza Mirza | - | Sell | 5,000 | Common Stock | $16.05 | $80,250.00 | 0.68 [ Average ] | 10,000 | $160,500.00 | 1.36 [Low] | Form 4 | - | 2020-12-07 | Mansoor Raza Mirza | - | Sell | 5,000 | Common Stock | $16.04 | $80,200.00 | 0.68 [ Average ] | 5,000 | $80,200.00 | 0.68 [Very Low] | Form 4 | - | 2020-12-07 | Mansoor Raza Mirza | - | Sell | 5,000 | Common Stock | $16.14 | $80,700.00 | 0.68 [ Average ] | 0 | $0.00 | - | Form 4 | - | 2020-12-18 | Mansoor Raza Mirza | - | Buy | 5,000 | Common Stock | $5.43 | -$27,150.00 | 0.68 [ Average ] | 5,000 | $27,150.00 | 0.68 [Very Low] | Form 4 | - | 2020-12-18 | Mansoor Raza Mirza | - | Sell | 5,000 | Common Stock | $18.00 | $90,000.00 | 0.68 [ Average ] | 0 | $0.00 | - | Form 4 | - | 2021-02-05 | Michael Kauffman | Chief Executive Officer | Buy | 14,300 | Common Stock | $0.00 | $0.00 | - | 569,422 | $0.00 | 77.37 [High] | Form 4 | - | 2021-02-05 | Michael Kauffman | Chief Executive Officer | Buy | 14,300 | Common Stock | $0.00 | $0.00 | - | 770,789 | $0.00 | 104.73 [Very High] | Form 4 | By Spouse | 2021-02-05 | Tanya Lewis | EVP, Chief Reg. Affairs | Buy | 5,650 | Common Stock | $0.00 | $0.00 | - | 6,189 | $0.00 | 0.84 [Very Low] | Form 4 | - | 2021-02-05 | Sharon Shacham | President & CSO | Buy | 14,300 | Common Stock | $0.00 | $0.00 | - | 770,789 | $0.00 | 104.73 [Very High] | Form 4 | - | 2021-02-05 | Sharon Shacham | President & CSO | Buy | 14,300 | Common Stock | $0.00 | $0.00 | - | 569,422 | $0.00 | 77.37 [High] | Form 4 | By Spouse | 2021-02-05 | Michael Mason | SVP, CFO & Treasurer | Buy | 8,150 | Common Stock | $0.00 | $0.00 | - | 8,150 | $0.00 | 1.11 [Very Low] | Form 4 | - | 2021-02-05 | Ran Frenkel | EVP, Chief Dev. Officer | Buy | 5,650 | Common Stock | $0.00 | $0.00 | - | 41,384 | $0.00 | 5.62 [Average] | Form 4 | - | 2021-02-05 | Jatin Shah | EVP, Chief Medical Officer | Buy | 5,650 | Common Stock | $0.00 | $0.00 | - | 49,875 | $0.00 | 6.78 [Average] | Form 4 | - | 2021-02-11 | Michael Kauffman | Chief Executive Officer | Sell | 6,601 | Common Stock | $15.52 | $102,447.52 | 0.90 [ High ] | 562,821 | $8,734,981.92 | 76.47 [High] | Form 4 | - | 2021-02-15 | Michael Kauffman | Chief Executive Officer | Buy | 21,800 | Common Stock | $0.00 | $0.00 | - | 584,621 | $0.00 | 79.43 [Very High] | Form 4 | - | 2021-02-11 | Michael Kauffman | Chief Executive Officer | Sell | 6,642 | Common Stock | $15.52 | $103,083.84 | 0.90 [ High ] | 764,147 | $11,859,561.44 | 103.82 [Very High] | Form 4 | By Spouse | 2021-02-15 | Michael Kauffman | Chief Executive Officer | Buy | 21,800 | Common Stock | $0.00 | $0.00 | - | 785,947 | $0.00 | 106.78 [Very High] | Form 4 | By Spouse | 2021-02-11 | Tanya Lewis | EVP, Chief Reg. Affairs | Sell | 2,046 | Common Stock | $15.52 | $31,753.92 | 0.28 [ Low ] | 4,143 | $64,299.36 | 0.56 [Very Low] | Form 4 | - | 2021-02-11 | Sharon Shacham | President & CSO | Sell | 6,642 | Common Stock | $15.52 | $103,083.84 | 0.90 [ High ] | 764,147 | $11,859,561.44 | 103.82 [Very High] | Form 4 | - | 2021-02-15 | Sharon Shacham | President & CSO | Buy | 21,800 | Common Stock | $0.00 | $0.00 | - | 785,947 | $0.00 | 106.78 [Very High] | Form 4 | - | 2021-02-11 | Sharon Shacham | President & CSO | Sell | 6,601 | Common Stock | $15.52 | $102,447.52 | 0.90 [ High ] | 562,821 | $8,734,981.92 | 76.47 [High] | Form 4 | By Spouse | 2021-02-15 | Sharon Shacham | President & CSO | Buy | 21,800 | Common Stock | $0.00 | $0.00 | - | 584,621 | $0.00 | 79.43 [Very High] | Form 4 | By Spouse | 2021-02-11 | Michael Mason | SVP, CFO & Treasurer | Sell | 2,858 | Common Stock | $15.52 | $44,356.16 | 0.39 [ Average ] | 5,292 | $82,131.84 | 0.72 [Very Low] | Form 4 | - | 2021-02-11 | Ran Frenkel | EVP, Chief Dev. Officer | Sell | 2,046 | Common Stock | $15.52 | $31,753.92 | 0.28 [ Low ] | 39,338 | $610,525.76 | 5.34 [Average] | Form 4 | - | 2021-02-15 | Ran Frenkel | EVP, Chief Dev. Officer | Buy | 9,675 | Common Stock | $0.00 | $0.00 | - | 49,013 | $0.00 | 6.66 [Average] | Form 4 | - | 2021-02-11 | Jatin Shah | EVP, Chief Medical Officer | Sell | 1,748 | Common Stock | $15.52 | $27,128.96 | 0.24 [ Low ] | 48,127 | $746,931.04 | 6.54 [Average] | Form 4 | - | 2021-02-15 | Jatin Shah | EVP, Chief Medical Officer | Buy | 4,850 | Common Stock | $0.00 | $0.00 | - | 52,977 | $0.00 | 7.20 [Average] | Form 4 | - | 2021-02-18 | Michael Kauffman | Chief Executive Officer | Sell | 9,495 | Common Stock | $14.83 | $140,810.85 | 1.28 [ High ] | 575,126 | $8,529,118.58 | 77.80 [Very High] | Form 4 | - | 2021-02-18 | Michael Kauffman | Chief Executive Officer | Sell | 9,495 | Common Stock | $14.83 | $140,810.85 | 1.28 [ High ] | 776,452 | $11,514,783.16 | 105.04 [Very High] | Form 4 | By Spouse | 2021-02-18 | Sharon Shacham | President & CSO | Sell | 9,495 | Common Stock | $14.83 | $140,810.85 | 1.28 [ High ] | 776,452 | $11,514,783.16 | 105.04 [Very High] | Form 4 | - | 2021-02-18 | Sharon Shacham | President & CSO | Sell | 9,495 | Common Stock | $14.83 | $140,810.85 | 1.28 [ High ] | 575,126 | $8,529,118.58 | 77.80 [Very High] | Form 4 | By Spouse | 2021-02-18 | Ran Frenkel | EVP, Chief Dev. Officer | Sell | 2,887 | Common Stock | $14.83 | $42,814.21 | 0.39 [ Average ] | 46,126 | $684,048.58 | 6.24 [Average] | Form 4 | - | 2021-02-18 | Jatin Shah | EVP, Chief Medical Officer | Sell | 1,186 | Common Stock | $14.83 | $17,588.38 | 0.16 [ Low ] | 51,791 | $768,060.53 | 7.01 [Average] | Form 4 | - |
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