| Trade Date | Insider | Title | Buy or Sell | Quantity | Security Type | Price | Proceeds | Transaction Conviction | Position Quantity | Position Value | Positon Conviction | SEC Link | Nature of Ownership | 2020-07-06 | Peter M Carlson | Chief Financial Officer | Buy | 35,211 | Common Stock | $5.40 | -$190,139.40 | 3.17 [ Very High ] | 84,506 | $456,332.40 | 7.61 [Average] | Form 4 | - | 2020-04-26 | Mark Graves | SVP & Chief Compliance Officer | Sell | 3,363 | Common Stock | $3.79 | $12,745.77 | 0.30 [ Average ] | 44,735 | $169,545.65 | 4.03 [Low] | Form 4 | - | 2020-04-26 | Scott M Turner | SVP, Operations & Procurement | Sell | 5,067 | Common Stock | $3.79 | $19,203.93 | 0.46 [ Average ] | 104,843 | $397,354.97 | 9.44 [Average] | Form 4 | - | 2020-06-07 | Timothy R Wright | Chief Executive Officer | Sell | 89,591 | Common Stock | $3.50 | $313,568.50 | - | 592,227 | $2,072,794.50 | - | Form 4 | - | 2020-08-03 | Rohit Kashyap | EVP & Chief Commercial Officer | Buy | 173,310 | Common Stock | $5.77 | -$999,998.70 | 15.61 [ Very High ] | 173,310 | $999,998.70 | 15.61 [High] | Form 4 | - | 2020-08-05 | J Terry Dewberry | - | Buy | 29,661 | Common Stock | $0.00 | $0.00 | - | 156,787 | $0.00 | 14.12 [Average] | Form 4 | - | 2020-08-05 | James L Bierman | - | Buy | 38,135 | Common Stock | $0.00 | $0.00 | - | 38,135 | $0.00 | 3.43 [Low] | Form 4 | - | 2020-08-05 | M Kathleen Behrens | - | Buy | 38,135 | Common Stock | $0.00 | $0.00 | - | 38,135 | $0.00 | 3.43 [Low] | Form 4 | - | 2020-08-05 | Timothy R Wright | Chief Executive Officer | Buy | 572,033 | Common Stock | $0.00 | $0.00 | - | 1,164,260 | $0.00 | 104.86 [Very High] | Form 4 | - | 2020-08-05 | Charles Robert Evans | - | Buy | 29,661 | Common Stock | $0.00 | $0.00 | - | 95,121 | $0.00 | 8.57 [Average] | Form 4 | - | 2020-08-05 | Neil Yeston | - | Buy | 29,661 | Common Stock | $0.00 | $0.00 | - | 100,121 | $0.00 | 9.02 [Average] | Form 4 | - | 2020-08-05 | Richard Barry | - | Buy | 38,135 | Common Stock | $0.00 | $0.00 | - | 3,338,135 | $0.00 | 300.64 [Very High] | Form 4 | Shares are held in trust | 2020-08-05 | Charles E Koob | - | Buy | 29,661 | Common Stock | $0.00 | $0.00 | - | 1,505,289 | $0.00 | 135.57 [Very High] | Form 4 | by Family Trust | 2020-08-05 | Todd Newton | - | Buy | 38,135 | Common Stock | $0.00 | $0.00 | - | 38,135 | $0.00 | 3.43 [Low] | Form 4 | - | 2020-08-05 | Peter M Carlson | Chief Financial Officer | Buy | 177,966 | Common Stock | $0.00 | $0.00 | - | 262,472 | $0.00 | 23.64 [High] | Form 4 | - | 2020-08-05 | Scott M Turner | SVP, Operations & Procurement | Buy | 48,135 | Common Stock | $0.00 | $0.00 | - | 152,978 | $0.00 | 13.78 [Average] | Form 4 | - | 2020-08-05 | Hulse William Frank Iv | General Counsel | Buy | 120,762 | Common Stock | $0.00 | $0.00 | - | 120,762 | $0.00 | 10.88 [Average] | Form 4 | - | 2020-08-05 | Mark Graves | SVP & Chief Compliance Officer | Buy | 35,254 | Common Stock | $0.00 | $0.00 | - | 79,989 | $0.00 | 7.20 [Average] | Form 4 | - | 2020-08-05 | William Lawrence Phelan | Chief Accounting Officer | Buy | 59,322 | Common Stock | $0.00 | $0.00 | - | 59,322 | $0.00 | 5.34 [Average] | Form 4 | - | 2020-08-10 | Robert Benjamin Stein | EVP, Research and Development | Buy | 81,833 | Common Stock | $6.11 | -$499,999.63 | 7.37 [ Very High ] | 81,833 | $499,999.63 | 7.37 [Average] | Form 4 | - | 2020-07-21 | William A Hawkins | - | Buy | 13,418 | Common Stock | $5.90 | -$79,166.20 | 1.21 [ High ] | 13,418 | $79,166.20 | 1.21 [Very Low] | Form 4 | - | 2020-09-21 | Charles E Koob | - | Sell | 50,000 | Common Stock | $0.00 | $0.00 | - | 1,455,289 | $0.00 | 131.07 [Very High] | Form 4 | by Family Trust | 2020-09-21 | Charles E Koob | - | Sell | 50,000 | Common Stock | $0.00 | $0.00 | - | 1,405,289 | $0.00 | 126.56 [Very High] | Form 4 | by Family Trust | 2020-10-02 | William A Hawkins | - | Buy | 26,236 | Common Stock | $6.67 | -$174,994.12 | 2.36 [ High ] | 39,654 | $264,492.18 | 3.57 [Low] | Form 4 | - | 2020-10-02 | James L Bierman | - | Buy | 26,236 | Common Stock | $6.67 | -$174,994.12 | 2.36 [ High ] | 64,371 | $429,354.57 | 5.80 [Average] | Form 4 | - | 2020-10-02 | M Kathleen Behrens | - | Buy | 26,236 | Common Stock | $6.67 | -$174,994.12 | 2.36 [ High ] | 64,371 | $429,354.57 | 5.80 [Average] | Form 4 | - | 2020-10-02 | Charles Robert Evans | - | Buy | 26,236 | Common Stock | $6.67 | -$174,994.12 | 2.36 [ High ] | 121,357 | $809,451.19 | 10.93 [Average] | Form 4 | - | 2020-10-02 | Charles E Koob | - | Buy | 26,236 | Common Stock | $6.67 | -$174,994.12 | 2.36 [ High ] | 1,431,525 | $9,548,271.75 | 128.93 [Very High] | Form 4 | by Family Trust | 2020-10-02 | Todd Newton | - | Buy | 26,236 | Common Stock | $6.67 | -$174,994.12 | 2.36 [ High ] | 64,371 | $429,354.57 | 5.80 [Average] | Form 4 | - | 2020-10-02 | Neil Yeston | - | Buy | 26,236 | Common Stock | $6.67 | -$174,994.12 | 2.36 [ High ] | 126,357 | $842,801.19 | 11.38 [Average] | Form 4 | - | 2020-10-26 | Scott M Turner | SVP, Operations & Procurement | Sell | 301 | Common Stock | $5.91 | $1,778.91 | 0.03 [ Very Low ] | 152,677 | $902,321.07 | 13.75 [Average] | Form 4 | - | 2020-11-04 | Peter M Carlson | Chief Financial Officer | Buy | 35,211 | Common Stock | $7.23 | -$254,575.53 | 3.17 [ Very High ] | 297,683 | $2,152,248.09 | 26.81 [High] | Form 4 | - | 2020-11-04 | William Lawrence Phelan | Chief Accounting Officer | Buy | 8,474 | Common Stock | $7.23 | -$61,267.02 | 0.76 [ Average ] | 67,796 | $490,165.08 | 6.11 [Average] | Form 4 | - | 2020-12-16 | William A Hawkins | - | Buy | 15,964 | Common Stock | $7.83 | -$124,998.12 | 1.44 [ High ] | 55,618 | $435,488.94 | 5.01 [Average] | Form 4 | - | 2020-12-16 | Michael J Giuliani | - | Buy | 22,349 | Common Stock | $7.83 | -$174,992.67 | 2.01 [ High ] | 22,349 | $174,992.67 | 2.01 [Low] | Form 4 | - | 2020-12-16 | Michael J Giuliani | - | Buy | 11,174 | Common Stock | $7.83 | -$87,492.42 | 1.01 [ High ] | 33,523 | $262,485.09 | 3.02 [Low] | Form 4 | - | 2020-12-16 | Cato T Laurencin | - | Buy | 22,349 | Common Stock | $7.83 | -$174,992.67 | 2.01 [ High ] | 22,349 | $174,992.67 | 2.01 [Low] | Form 4 | - | 2020-12-16 | Cato T Laurencin | - | Buy | 11,174 | Common Stock | $7.83 | -$87,492.42 | 1.01 [ High ] | 33,523 | $262,485.09 | 3.02 [Low] | Form 4 | - | 2021-02-18 | Timothy R Wright | Chief Executive Officer | Sell | 70,200 | Common Stock | $9.81 | $688,662.00 | 6.32 [ Very High ] | 1,094,060 | $10,732,728.60 | 98.52 [Very High] | Form 4 | - | 2021-02-18 | Peter M Carlson | Chief Financial Officer | Sell | 18,015 | Common Stock | $9.81 | $176,727.15 | 1.62 [ High ] | 279,668 | $2,743,543.08 | 25.19 [High] | Form 4 | - | 2021-02-18 | Scott M Turner | SVP, Operations & Procurement | Sell | 5,278 | Common Stock | $9.81 | $51,777.18 | 0.48 [ Average ] | 147,399 | $1,445,984.19 | 13.27 [Average] | Form 4 | - | 2021-02-18 | Hulse William Frank Iv | General Counsel | Sell | 10,231 | Common Stock | $9.81 | $100,366.11 | 0.92 [ High ] | 110,531 | $1,084,309.11 | 9.95 [Average] | Form 4 | - | 2021-02-18 | Mark Graves | SVP & Chief Compliance Officer | Sell | 4,060 | Common Stock | $9.81 | $39,828.60 | 0.37 [ Average ] | 75,929 | $744,863.49 | 6.84 [Average] | Form 4 | - | 2021-02-22 | Scott M Turner | SVP, Operations & Procurement | Sell | 1,572 | Common Stock | $9.98 | $15,688.56 | 0.14 [ Low ] | 145,827 | $1,455,353.46 | 13.13 [Average] | Form 4 | - | 2021-03-04 | Timothy R Wright | Chief Executive Officer | Buy | 335,153 | Common Stock | $0.00 | $0.00 | - | 1,429,213 | $0.00 | 128.71 [Very High] | Form 4 | - | 2021-03-04 | Robert Benjamin Stein | EVP, Research and Development | Buy | 109,235 | Common Stock | $0.00 | $0.00 | - | 191,068 | $0.00 | 17.21 [High] | Form 4 | - | 2021-03-04 | Peter M Carlson | Chief Financial Officer | Buy | 109,235 | Common Stock | $0.00 | $0.00 | - | 388,903 | $0.00 | 35.02 [High] | Form 4 | - | 2021-03-04 | Rohit Kashyap | EVP & Chief Commercial Officer | Buy | 99,304 | Common Stock | $0.00 | $0.00 | - | 272,614 | $0.00 | 24.55 [High] | Form 4 | - | 2021-03-04 | Scott M Turner | SVP, Operations & Procurement | Buy | 39,721 | Common Stock | $0.00 | $0.00 | - | 185,548 | $0.00 | 16.71 [High] | Form 4 | - | 2021-03-04 | Hulse William Frank Iv | General Counsel | Buy | 99,304 | Common Stock | $0.00 | $0.00 | - | 209,835 | $0.00 | 18.90 [High] | Form 4 | - | 2021-03-04 | Mark Graves | SVP & Chief Compliance Officer | Buy | 27,308 | Common Stock | $0.00 | $0.00 | - | 103,237 | $0.00 | 9.30 [Average] | Form 4 | - | 2021-03-04 | William Lawrence Phelan | Chief Accounting Officer | Buy | 29,791 | Common Stock | $0.00 | $0.00 | - | 97,587 | $0.00 | 8.79 [Average] | Form 4 | - | 2021-04-26 | Scott M Turner | SVP, Operations & Procurement | Sell | 5,224 | Common Stock | $10.63 | $55,531.12 | 0.47 [ Average ] | 180,324 | $1,916,844.12 | 16.14 [High] | Form 4 | - | 2021-04-26 | Mark Graves | SVP & Chief Compliance Officer | Sell | 3,467 | Common Stock | $10.63 | $36,854.21 | 0.31 [ Average ] | 99,770 | $1,060,555.10 | 8.93 [Average] | Form 4 | - | 2021-04-28 | Phyllis Gardner | - | Buy | 16,339 | Common Stock | $10.71 | -$174,990.69 | 1.46 [ High ] | 16,339 | $174,990.69 | 1.46 [Low] | Form 4 | - | 2021-04-28 | Phyllis Gardner | - | Buy | 4,084 | Common Stock | $10.71 | -$43,739.64 | 0.37 [ Average ] | 20,423 | $218,730.33 | 1.83 [Low] | Form 4 | - | 2021-05-01 | William Lawrence Phelan | Chief Accounting Officer | Sell | 5,433 | Common Stock | $9.70 | $52,700.10 | 0.49 [ Average ] | 92,154 | $893,893.80 | 8.25 [Average] | Form 4 | - 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