Opko Health, Inc.

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Opko Health, Inc.

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Trade Date Insider Title Buy or Sell Quantity Security Type Price Proceeds Transaction Conviction Position Quantity Position Value Positon Conviction SEC Link Nature of Ownership
2020-04-01Frost Phillip Md Et AlCEO & ChairmanBuy143,549Common Stock$1.20-$172,258.80  2.14     [ High ]187,271,694$224,726,032.80  2,795.81 [Very High]Form 4See Footnote
2020-04-01Frost Phillip Md Et AlCEO & ChairmanBuy200,000Common Stock$1.22-$244,000.00  2.99     [ Very High ]187,471,694$228,715,466.68  2,798.80 [Very High]Form 4See Footnote
2020-04-01Frost Phillip Md Et AlCEO & ChairmanBuy100,000Common Stock$1.25-$125,000.00  1.49     [ High ]187,571,694$234,464,617.50  2,800.29 [Very High]Form 4See Footnote
2020-04-01Frost Phillip Md Et AlCEO & ChairmanBuy49,308Common Stock$1.25-$61,635.00  0.74     [ Average ]187,621,002$234,526,252.50  2,801.03 [Very High]Form 4See Footnote
2020-04-01Frost Phillip Md Et AlCEO & ChairmanBuy150,692Common Stock$1.26-$189,871.92  2.25     [ High ]187,771,694$236,592,334.44  2,803.28 [Very High]Form 4See Footnote
2020-04-02Frost Phillip Md Et AlCEO & ChairmanBuy105,653Common Stock$1.15-$121,500.95  1.58     [ High ]187,877,347$216,058,949.05  2,804.86 [Very High]Form 4See Footnote
2020-04-02Frost Phillip Md Et AlCEO & ChairmanBuy94,347Common Stock$1.15-$108,499.05  1.41     [ High ]187,971,694$216,167,448.10  2,806.26 [Very High]Form 4See Footnote
2020-04-02Frost Phillip Md Et AlCEO & ChairmanBuy47,443Common Stock$1.16-$55,033.88  0.71     [ Average ]188,019,137$218,102,198.92  2,806.97 [Very High]Form 4See Footnote
2020-04-02Frost Phillip Md Et AlCEO & ChairmanBuy50,136Common Stock$1.16-$58,157.76  0.75     [ Average ]188,069,273$218,160,356.68  2,807.72 [Very High]Form 4See Footnote
2020-04-02Frost Phillip Md Et AlCEO & ChairmanBuy102,421Common Stock$1.17-$119,832.57  1.53     [ High ]188,171,694$220,160,881.98  2,809.25 [Very High]Form 4See Footnote
2020-04-02Frost Phillip Md Et AlCEO & ChairmanBuy14,788Common Stock$1.19-$17,597.72  0.22     [ Low ]188,186,482$223,941,913.58  2,809.47 [Very High]Form 4See Footnote
2020-04-02Frost Phillip Md Et AlCEO & ChairmanBuy85,212Common Stock$1.19-$101,402.28  1.27     [ High ]188,271,694$224,043,315.86  2,810.74 [Very High]Form 4See Footnote
2020-04-03Frost Phillip Md Et AlCEO & ChairmanBuy39,790Common Stock$1.15-$45,758.50  0.59     [ Average ]188,311,484$216,558,206.60  2,811.34 [Very High]Form 4See Footnote
2020-04-03Frost Phillip Md Et AlCEO & ChairmanBuy1,969Common Stock$1.16-$2,284.04  0.03     [ Very Low ]188,313,453$218,443,605.48  2,811.37 [Very High]Form 4See Footnote
2020-04-03Frost Phillip Md Et AlCEO & ChairmanBuy8,241Common Stock$1.16-$9,559.56  0.12     [ Low ]188,321,694$218,453,165.04  2,811.49 [Very High]Form 4See Footnote
2020-04-07Frost Phillip Md Et AlCEO & ChairmanBuy11,932Common Stock$1.25-$14,915.00  0.18     [ Low ]188,333,626$235,417,032.50  2,811.67 [Very High]Form 4See Footnote
2020-04-07Frost Phillip Md Et AlCEO & ChairmanBuy63,068Common Stock$1.26-$79,465.68  0.94     [ High ]188,396,694$237,379,834.44  2,812.61 [Very High]Form 4See Footnote
2020-04-07Frost Phillip Md Et AlCEO & ChairmanBuy1,700Common Stock$1.26-$2,142.00  0.03     [ Very Low ]188,398,394$237,381,976.44  2,812.63 [Very High]Form 4See Footnote
2020-04-07Frost Phillip Md Et AlCEO & ChairmanBuy37,753Common Stock$1.27-$47,946.31  0.56     [ Average ]188,436,147$239,313,906.69  2,813.20 [Very High]Form 4See Footnote
2020-04-07Frost Phillip Md Et AlCEO & ChairmanBuy18,263Common Stock$1.27-$23,194.01  0.27     [ Low ]188,454,410$239,337,100.70  2,813.47 [Very High]Form 4See Footnote
2020-04-07Frost Phillip Md Et AlCEO & ChairmanBuy164,384Common Stock$1.28-$210,411.52  2.45     [ Very High ]188,618,794$241,432,056.32  2,815.92 [Very High]Form 4See Footnote
2020-04-07Frost Phillip Md Et AlCEO & ChairmanBuy100Common Stock$1.28-$128.00  -188,618,894$241,432,184.32  2,815.93 [Very High]Form 4See Footnote
2020-04-07Frost Phillip Md Et AlCEO & ChairmanBuy52,619Common Stock$1.28-$67,352.32  0.79     [ High ]188,671,513$241,499,536.64  2,816.71 [Very High]Form 4See Footnote
2020-04-07Frost Phillip Md Et AlCEO & ChairmanBuy5,774Common Stock$1.29-$7,448.46  0.09     [ Low ]188,677,287$243,393,700.23  2,816.80 [Very High]Form 4See Footnote
2020-04-07Frost Phillip Md Et AlCEO & ChairmanBuy4,407Common Stock$1.29-$5,685.03  0.07     [ Very Low ]188,681,694$243,399,385.26  2,816.86 [Very High]Form 4See Footnote
2020-04-07Frost Phillip Md Et AlCEO & ChairmanBuy24,362Common Stock$1.29-$31,426.98  0.36     [ Average ]188,706,056$243,430,812.24  2,817.23 [Very High]Form 4See Footnote
2020-04-07Frost Phillip Md Et AlCEO & ChairmanBuy15,638Common Stock$1.30-$20,329.40  0.23     [ Low ]188,721,694$245,338,202.20  2,817.46 [Very High]Form 4See Footnote
2020-04-15Frost Phillip Md Et AlCEO & ChairmanBuy1,200Common Stock$1.49-$1,788.00  0.02     [ Very Low ]188,722,894$281,197,112.06  2,817.48 [Very High]Form 4See Footnote
2020-04-15Frost Phillip Md Et AlCEO & ChairmanBuy7,960Common Stock$1.49-$11,860.40  0.12     [ Low ]188,730,854$281,208,972.46  2,817.60 [Very High]Form 4See Footnote
2020-04-15Frost Phillip Md Et AlCEO & ChairmanBuy13,803Common Stock$1.50-$20,704.50  0.21     [ Low ]188,744,657$283,116,985.50  2,817.80 [Very High]Form 4See Footnote
2020-04-15Frost Phillip Md Et AlCEO & ChairmanBuy218Common Stock$1.50-$327.00  -188,744,875$283,117,312.50  2,817.81 [Very High]Form 4See Footnote
2020-04-15Frost Phillip Md Et AlCEO & ChairmanBuy26,300Common Stock$1.51-$39,713.00  0.39     [ Average ]188,771,175$285,044,474.25  2,818.20 [Very High]Form 4See Footnote
2020-04-15Frost Phillip Md Et AlCEO & ChairmanBuy24,663Common Stock$1.51-$37,241.13  0.37     [ Average ]188,795,838$285,081,715.38  2,818.57 [Very High]Form 4See Footnote
2020-04-15Frost Phillip Md Et AlCEO & ChairmanBuy2,900Common Stock$1.52-$4,408.00  0.04     [ Very Low ]188,798,738$286,974,081.76  2,818.61 [Very High]Form 4See Footnote
2020-04-15Frost Phillip Md Et AlCEO & ChairmanBuy22,956Common Stock$1.52-$34,893.12  0.34     [ Average ]188,821,694$287,008,974.88  2,818.95 [Very High]Form 4See Footnote
2020-04-15Frost Phillip Md Et AlCEO & ChairmanBuy2,200Common Stock$1.53-$3,366.00  0.03     [ Very Low ]188,823,894$288,900,557.82  2,818.99 [Very High]Form 4See Footnote
2020-04-15Frost Phillip Md Et AlCEO & ChairmanBuy10,146Common Stock$1.53-$15,523.38  0.15     [ Low ]188,834,040$288,916,081.20  2,819.14 [Very High]Form 4See Footnote
2020-04-15Frost Phillip Md Et AlCEO & ChairmanBuy32,159Common Stock$1.54-$49,524.86  0.48     [ Average ]188,866,199$290,853,946.46  2,819.62 [Very High]Form 4See Footnote
2020-04-15Frost Phillip Md Et AlCEO & ChairmanBuy5,495Common Stock$1.55-$8,517.25  0.08     [ Very Low ]188,871,694$292,751,125.70  2,819.70 [Very High]Form 4See Footnote
2020-04-15Frost Phillip Md Et AlCEO & ChairmanBuy2,000Common Stock$1.62-$3,240.00  0.03     [ Very Low ]188,873,694$305,975,384.28  2,819.73 [Very High]Form 4See Footnote
2020-04-15Frost Phillip Md Et AlCEO & ChairmanBuy39,573Common Stock$1.63-$64,503.99  0.59     [ Average ]188,913,267$307,928,625.21  2,820.32 [Very High]Form 4See Footnote
2020-04-15Frost Phillip Md Et AlCEO & ChairmanBuy2,378Common Stock$1.64-$3,899.92  0.04     [ Very Low ]188,915,645$309,821,657.80  2,820.36 [Very High]Form 4See Footnote
2020-04-15Frost Phillip Md Et AlCEO & ChairmanBuy6,049Common Stock$1.64-$9,920.36  0.09     [ Low ]188,921,694$309,831,578.16  2,820.45 [Very High]Form 4See Footnote
2020-04-16Frost Phillip Md Et AlCEO & ChairmanBuy2,407Common Stock$1.62-$3,899.34  0.04     [ Very Low ]188,924,101$306,057,043.62  2,820.48 [Very High]Form 4See Footnote
2020-04-16Frost Phillip Md Et AlCEO & ChairmanBuy22,593Common Stock$1.63-$36,826.59  0.34     [ Average ]188,946,694$307,983,111.22  2,820.82 [Very High]Form 4See Footnote
2020-04-17Frost Phillip Md Et AlCEO & ChairmanBuy100,000Common Stock$1.63-$163,000.00  1.49     [ High ]189,046,694$308,146,111.22  2,822.31 [Very High]Form 4See Footnote
2020-04-17Frost Phillip Md Et AlCEO & ChairmanBuy4,914Common Stock$1.66-$8,157.24  0.07     [ Very Low ]189,051,608$313,825,669.28  2,822.39 [Very High]Form 4See Footnote
2020-04-17Frost Phillip Md Et AlCEO & ChairmanBuy20,086Common Stock$1.66-$33,342.76  0.30     [ Average ]189,071,694$313,859,012.04  2,822.69 [Very High]Form 4See Footnote
2020-04-17Frost Phillip Md Et AlCEO & ChairmanBuy50,000Common Stock$1.67-$83,500.00  0.75     [ Average ]189,121,694$315,833,228.98  2,823.43 [Very High]Form 4See Footnote
2020-04-17Frost Phillip Md Et AlCEO & ChairmanBuy1,600Common Stock$1.68-$2,688.00  0.02     [ Very Low ]189,123,294$317,727,133.92  2,823.46 [Very High]Form 4See Footnote
2020-04-17Frost Phillip Md Et AlCEO & ChairmanBuy98,400Common Stock$1.68-$165,312.00  1.47     [ High ]189,221,694$317,892,445.92  2,824.93 [Very High]Form 4See Footnote
2020-04-17Frost Phillip Md Et AlCEO & ChairmanBuy20,600Common Stock$1.69-$34,814.00  0.31     [ Average ]189,242,294$319,819,476.86  2,825.23 [Very High]Form 4See Footnote
2020-04-17Frost Phillip Md Et AlCEO & ChairmanBuy29,400Common Stock$1.69-$49,686.00  0.44     [ Average ]189,271,694$319,869,162.86  2,825.67 [Very High]Form 4See Footnote
2020-05-26Frost Phillip Md Et AlCEO & ChairmanBuy50,000Common Stock$2.31-$115,500.00  0.75     [ High ]189,721,694$438,257,113.14  2,832.39 [Very High]Form 4See Footnote
2020-05-26Frost Phillip Md Et AlCEO & ChairmanBuy4,850Common Stock$2.33-$11,300.50  0.07     [ Very Low ]189,726,544$442,062,847.52  2,832.46 [Very High]Form 4See Footnote
2020-05-26Frost Phillip Md Et AlCEO & ChairmanBuy5,700Common Stock$2.34-$13,338.00  0.09     [ Low ]189,732,244$443,973,450.96  2,832.55 [Very High]Form 4See Footnote
2020-05-26Frost Phillip Md Et AlCEO & ChairmanBuy39,450Common Stock$2.34-$92,313.00  0.59     [ Average ]189,771,694$444,065,763.96  2,833.14 [Very High]Form 4See Footnote
2020-05-26Frost Phillip Md Et AlCEO & ChairmanBuy341Common Stock$2.35-$801.35  -189,772,035$445,964,282.25  2,833.14 [Very High]Form 4See Footnote
2020-05-26Frost Phillip Md Et AlCEO & ChairmanBuy22,319Common Stock$2.35-$52,449.65  0.33     [ Average ]189,794,354$446,016,731.90  2,833.47 [Very High]Form 4See Footnote
2020-05-26Frost Phillip Md Et AlCEO & ChairmanBuy1,000Common Stock$2.36-$2,360.00  -189,795,354$447,917,035.44  2,833.49 [Very High]Form 4See Footnote
2020-05-26Frost Phillip Md Et AlCEO & ChairmanBuy26,340Common Stock$2.36-$62,162.40  0.39     [ Average ]189,821,694$447,979,197.84  2,833.88 [Very High]Form 4See Footnote
2020-05-26Frost Phillip Md Et AlCEO & ChairmanBuy300Common Stock$2.36-$708.00  -189,821,994$447,979,905.84  2,833.89 [Very High]Form 4See Footnote
2020-05-26Frost Phillip Md Et AlCEO & ChairmanBuy11,776Common Stock$2.37-$27,909.12  0.18     [ Low ]189,833,770$449,906,034.90  2,834.06 [Very High]Form 4See Footnote
2020-05-26Frost Phillip Md Et AlCEO & ChairmanBuy9,336Common Stock$2.37-$22,126.32  0.14     [ Low ]189,843,106$449,928,161.22  2,834.20 [Very High]Form 4See Footnote
2020-05-26Frost Phillip Md Et AlCEO & ChairmanBuy20,541Common Stock$2.38-$48,887.58  0.31     [ Average ]189,863,647$451,875,479.86  2,834.51 [Very High]Form 4See Footnote
2020-05-26Frost Phillip Md Et AlCEO & ChairmanBuy700Common Stock$2.38-$1,666.00  -189,864,347$451,877,145.86  2,834.52 [Very High]Form 4See Footnote
2020-05-26Frost Phillip Md Et AlCEO & ChairmanBuy44,274Common Stock$2.38-$105,372.12  0.66     [ Average ]189,908,621$451,982,517.98  2,835.18 [Very High]Form 4See Footnote
2020-05-26Frost Phillip Md Et AlCEO & ChairmanBuy1,430Common Stock$2.38-$3,403.40  0.02     [ Very Low ]189,910,051$451,985,921.38  2,835.20 [Very High]Form 4See Footnote
2020-05-26Frost Phillip Md Et AlCEO & ChairmanBuy11,643Common Stock$2.39-$27,826.77  0.17     [ Low ]189,921,694$453,912,848.66  2,835.38 [Very High]Form 4See Footnote
2020-05-07Frost Phillip Md Et AlCEO & ChairmanBuy9,668Common Stock$2.04-$19,722.72  0.14     [ Low ]189,281,362$386,133,978.48  2,825.82 [Very High]Form 4See Footnote
2020-05-07Frost Phillip Md Et AlCEO & ChairmanBuy5,500Common Stock$2.04-$11,220.00  0.08     [ Very Low ]189,286,862$386,145,198.48  2,825.90 [Very High]Form 4See Footnote
2020-05-07Frost Phillip Md Et AlCEO & ChairmanBuy84,832Common Stock$2.04-$173,057.28  1.27     [ High ]189,371,694$386,318,255.76  2,827.16 [Very High]Form 4See Footnote
2020-05-07Frost Phillip Md Et AlCEO & ChairmanBuy100,000Common Stock$2.07-$207,000.00  1.49     [ High ]189,471,694$392,206,406.58  2,828.66 [Very High]Form 4See Footnote
2020-05-07Frost Phillip Md Et AlCEO & ChairmanBuy6,400Common Stock$2.08-$13,312.00  0.10     [ Low ]189,478,094$394,114,435.52  2,828.75 [Very High]Form 4See Footnote
2020-05-07Frost Phillip Md Et AlCEO & ChairmanBuy800Common Stock$2.08-$1,664.00  -189,478,894$394,116,099.52  2,828.77 [Very High]Form 4See Footnote
2020-05-07Frost Phillip Md Et AlCEO & ChairmanBuy4,400Common Stock$2.09-$9,196.00  0.07     [ Very Low ]189,483,294$396,020,084.46  2,828.83 [Very High]Form 4See Footnote
2020-05-07Frost Phillip Md Et AlCEO & ChairmanBuy200Common Stock$2.10-$420.00  -189,483,494$397,915,337.40  2,828.83 [Very High]Form 4See Footnote
2020-05-07Frost Phillip Md Et AlCEO & ChairmanBuy12,400Common Stock$2.10-$26,040.00  0.19     [ Low ]189,495,894$397,941,377.40  2,829.02 [Very High]Form 4See Footnote
2020-05-07Frost Phillip Md Et AlCEO & ChairmanBuy92,340Common Stock$2.10-$193,914.00  1.38     [ High ]189,588,234$398,135,291.40  2,830.40 [Very High]Form 4See Footnote
2020-05-07Frost Phillip Md Et AlCEO & ChairmanBuy2,388Common Stock$2.10-$5,014.80  0.04     [ Very Low ]189,590,622$398,140,306.20  2,830.43 [Very High]Form 4See Footnote
2020-05-07Frost Phillip Md Et AlCEO & ChairmanBuy13,700Common Stock$2.11-$28,907.00  0.20     [ Low ]189,604,322$400,065,119.42  2,830.64 [Very High]Form 4See Footnote
2020-05-07Frost Phillip Md Et AlCEO & ChairmanBuy51,760Common Stock$2.11-$109,213.60  0.77     [ High ]189,656,082$400,174,333.02  2,831.41 [Very High]Form 4See Footnote
2020-05-07Frost Phillip Md Et AlCEO & ChairmanBuy200Common Stock$2.11-$422.00  -189,656,282$400,174,755.02  2,831.41 [Very High]Form 4See Footnote
2020-05-07Frost Phillip Md Et AlCEO & ChairmanBuy15,112Common Stock$2.12-$32,037.44  0.23     [ Low ]189,671,394$402,103,355.28  2,831.64 [Very High]Form 4See Footnote
2020-05-07Frost Phillip Md Et AlCEO & ChairmanBuy300Common Stock$2.12-$636.00  -189,671,694$402,103,991.28  2,831.64 [Very High]Form 4See Footnote
2020-06-02Frost Phillip Md Et AlCEO & ChairmanBuy10,100Common Stock$2.41-$24,341.00  -190,031,794$457,976,623.54  -Form 4See Footnote
2020-06-02Frost Phillip Md Et AlCEO & ChairmanBuy21,400Common Stock$2.42-$51,788.00  -190,053,194$459,928,729.48  -Form 4See Footnote
2020-06-02Frost Phillip Md Et AlCEO & ChairmanBuy23,500Common Stock$2.42-$56,870.00  -190,076,694$459,985,599.48  -Form 4See Footnote
2020-06-02Frost Phillip Md Et AlCEO & ChairmanBuy4,391Common Stock$2.42-$10,626.22  -190,081,085$459,996,225.70  -Form 4See Footnote
2020-06-02Frost Phillip Md Et AlCEO & ChairmanBuy2,100Common Stock$2.43-$5,103.00  -190,083,185$461,902,139.55  -Form 4See Footnote
2020-06-02Frost Phillip Md Et AlCEO & ChairmanBuy13,509Common Stock$2.43-$32,826.87  -190,096,694$461,934,966.42  -Form 4See Footnote
2020-06-02Frost Phillip Md Et AlCEO & ChairmanBuy16,427Common Stock$2.44-$40,081.88  -190,113,121$463,876,015.24  -Form 4See Footnote
2020-06-02Frost Phillip Md Et AlCEO & ChairmanBuy3,573Common Stock$2.44-$8,718.12  -190,116,694$463,884,733.36  -Form 4See Footnote
2020-06-02Frost Phillip Md Et AlCEO & ChairmanBuy4,558Common Stock$2.44-$11,121.52  -190,121,252$463,895,854.88  -Form 4See Footnote
2020-06-02Frost Phillip Md Et AlCEO & ChairmanBuy442Common Stock$2.45-$1,082.90  -190,121,694$465,798,150.30  -Form 4See Footnote
2020-06-03Frost Phillip Md Et AlCEO & ChairmanBuy100,000Common Stock$2.27-$227,000.00  -190,221,694$431,803,245.38  -Form 4See Footnote
2020-08-26Steven D RubinExecutive VP-AdministrationBuy5,000Common Stock$3.99-$19,950.00  0.07     [ Very Low ]6,162,732$24,589,300.68  92.00    [Very High]Form 4-
2020-08-26Steven D RubinExecutive VP-AdministrationBuy2,500Common Stock$3.99-$9,975.00  0.04     [ Very Low ]6,165,232$24,599,275.68  92.04    [Very High]Form 4-
2020-08-26Steven D RubinExecutive VP-AdministrationBuy2,500Common Stock$4.01-$10,025.00  0.04     [ Very Low ]6,167,732$24,732,605.32  92.08    [Very High]Form 4-
2020-10-30Frost Phillip Md Et AlCEO & ChairmanBuy600,000Common Stock$3.45-$2,070,000.00  8.96     [ Very High ]190,821,694$658,334,844.30  2,848.08 [Very High]Form 4See Footnote
2020-11-09Frost Phillip Md Et AlCEO & ChairmanBuy1,500Common Stock$3.02-$4,530.00  0.02     [ Very Low ]190,823,194$576,286,045.88  2,848.11 [Very High]Form 4See Footnote
2020-11-09Frost Phillip Md Et AlCEO & ChairmanBuy6,172Common Stock$3.04-$18,762.88  0.09     [ Very Low ]190,829,366$580,121,272.64  2,848.20 [Very High]Form 4See Footnote
2020-11-09Frost Phillip Md Et AlCEO & ChairmanBuy13,700Common Stock$3.05-$41,785.00  0.20     [ Low ]190,843,066$582,071,351.30  2,848.40 [Very High]Form 4See Footnote
2020-11-09Frost Phillip Md Et AlCEO & ChairmanBuy30,128Common Stock$3.05-$91,890.40  0.45     [ Average ]190,873,194$582,163,241.70  2,848.85 [Very High]Form 4See Footnote
2020-11-09Frost Phillip Md Et AlCEO & ChairmanBuy600Common Stock$3.08-$1,848.00  -190,873,794$587,891,285.52  2,848.86 [Very High]Form 4See Footnote
2020-11-09Frost Phillip Md Et AlCEO & ChairmanBuy32,870Common Stock$3.09-$101,568.30  0.49     [ Average ]190,906,664$589,901,591.76  2,849.35 [Very High]Form 4See Footnote
2020-11-09Frost Phillip Md Et AlCEO & ChairmanBuy300Common Stock$3.10-$930.00  -190,906,964$591,811,588.40  2,849.36 [Very High]Form 4See Footnote
2020-11-09Frost Phillip Md Et AlCEO & ChairmanBuy3,400Common Stock$3.10-$10,540.00  0.05     [ Very Low ]190,910,364$591,822,128.40  2,849.41 [Very High]Form 4See Footnote
2020-11-09Frost Phillip Md Et AlCEO & ChairmanBuy2,200Common Stock$3.11-$6,842.00  0.03     [ Very Low ]190,912,564$593,738,074.04  2,849.44 [Very High]Form 4See Footnote
2020-11-09Frost Phillip Md Et AlCEO & ChairmanBuy1,300Common Stock$3.12-$4,056.00  0.02     [ Very Low ]190,913,864$595,651,255.68  2,849.46 [Very High]Form 4See Footnote
2020-11-09Frost Phillip Md Et AlCEO & ChairmanBuy600Common Stock$3.12-$1,872.00  -190,914,464$595,653,127.68  2,849.47 [Very High]Form 4See Footnote
2020-11-09Frost Phillip Md Et AlCEO & ChairmanBuy2,600Common Stock$3.13-$8,138.00  0.04     [ Very Low ]190,917,064$597,570,410.32  2,849.51 [Very High]Form 4See Footnote
2020-11-09Frost Phillip Md Et AlCEO & ChairmanBuy500Common Stock$3.13-$1,565.00  -190,917,564$597,571,975.32  2,849.52 [Very High]Form 4See Footnote
2020-11-09Frost Phillip Md Et AlCEO & ChairmanBuy11,900Common Stock$3.14-$37,366.00  0.18     [ Low ]190,929,464$599,518,516.96  2,849.69 [Very High]Form 4See Footnote
2020-11-09Frost Phillip Md Et AlCEO & ChairmanBuy10,000Common Stock$3.19-$31,900.00  0.15     [ Low ]190,939,464$609,096,890.16  2,849.84 [Very High]Form 4See Footnote
2020-11-09Frost Phillip Md Et AlCEO & ChairmanBuy39,500Common Stock$3.23-$127,585.00  0.59     [ Average ]190,978,964$616,862,053.72  2,850.43 [Very High]Form 4See Footnote
2020-11-09Frost Phillip Md Et AlCEO & ChairmanBuy26,800Common Stock$3.24-$86,832.00  0.40     [ Average ]191,005,764$618,858,675.36  2,850.83 [Very High]Form 4See Footnote
2020-11-09Frost Phillip Md Et AlCEO & ChairmanBuy13,700Common Stock$3.25-$44,525.00  0.20     [ Low ]191,019,464$620,813,258.00  2,851.04 [Very High]Form 4See Footnote
2020-11-09Frost Phillip Md Et AlCEO & ChairmanBuy17,230Common Stock$3.26-$56,169.80  0.26     [ Low ]191,036,694$622,779,622.44  2,851.29 [Very High]Form 4See Footnote
2020-11-09Frost Phillip Md Et AlCEO & ChairmanBuy450Common Stock$3.29-$1,480.50  -191,037,144$628,512,203.76  2,851.30 [Very High]Form 4See Footnote
2020-11-09Frost Phillip Md Et AlCEO & ChairmanBuy3,950Common Stock$3.29-$12,995.50  0.06     [ Very Low ]191,041,094$628,525,199.26  2,851.36 [Very High]Form 4See Footnote
2020-11-09Frost Phillip Md Et AlCEO & ChairmanBuy20,600Common Stock$3.30-$67,980.00  0.31     [ Average ]191,061,694$630,503,590.20  2,851.67 [Very High]Form 4See Footnote
2020-11-09Frost Phillip Md Et AlCEO & ChairmanBuy10,000Common Stock$3.32-$33,200.00  0.15     [ Low ]191,071,694$634,358,024.08  2,851.82 [Very High]Form 4See Footnote
2020-12-28Frost Phillip Md Et AlCEO & ChairmanBuy100,000Common Stock$3.96-$396,000.00  1.49     [ High ]191,171,694$757,039,908.24  2,853.31 [Very High]Form 4See Footnote
2020-12-28Frost Phillip Md Et AlCEO & ChairmanBuy50,000Common Stock$3.98-$199,000.00  0.75     [ Average ]191,221,694$761,062,342.12  2,854.06 [Very High]Form 4See Footnote
2020-12-28Frost Phillip Md Et AlCEO & ChairmanBuy150,000Common Stock$4.03-$604,500.00  2.24     [ High ]191,371,694$771,227,926.82  2,856.29 [Very High]Form 4See Footnote
2021-01-25Robert Scott Fishel-Buy40,000Common Stock$3.04-$121,600.00  0.60     [ Average ]40,000$121,600.00  0.60     [Very Low]Form 4-
2021-01-25Robert Scott Fishel-Buy20,000Common Stock$2.03-$40,600.00  0.30     [ Average ]60,000$121,800.00  0.90     [Very Low]Form 4-
2021-02-19Frost Phillip Md Et AlCEO & ChairmanBuy8,700Common Stock$4.71-$40,977.00  0.13     [ Low ]191,380,394$901,401,655.74  2,856.27 [Very High]Form 4See Footnote
2021-02-19Frost Phillip Md Et AlCEO & ChairmanBuy3,496Common Stock$4.71-$16,466.16  0.05     [ Very Low ]191,383,890$901,418,121.90  2,856.33 [Very High]Form 4See Footnote
2021-02-19Frost Phillip Md Et AlCEO & ChairmanBuy24,204Common Stock$4.72-$114,242.88  0.36     [ Average ]191,408,094$903,446,203.68  2,856.69 [Very High]Form 4See Footnote
2021-02-19Frost Phillip Md Et AlCEO & ChairmanBuy1,000Common Stock$4.72-$4,720.00  -191,409,094$903,450,923.68  2,856.70 [Very High]Form 4See Footnote
2021-02-19Frost Phillip Md Et AlCEO & ChairmanBuy17,589Common Stock$4.73-$83,195.97  0.26     [ Low ]191,426,683$905,448,210.59  2,856.97 [Very High]Form 4See Footnote
2021-02-19Frost Phillip Md Et AlCEO & ChairmanBuy10,204Common Stock$4.74-$48,366.96  0.15     [ Low ]191,436,887$907,410,844.38  2,857.12 [Very High]Form 4See Footnote
2021-02-19Frost Phillip Md Et AlCEO & ChairmanBuy73,207Common Stock$4.74-$347,001.18  1.09     [ High ]191,510,094$907,757,845.56  2,858.21 [Very High]Form 4See Footnote
2021-02-19Frost Phillip Md Et AlCEO & ChairmanBuy1,320Common Stock$4.75-$6,270.00  0.02     [ Very Low ]191,511,414$909,679,216.50  2,858.23 [Very High]Form 4See Footnote
2021-02-19Frost Phillip Md Et AlCEO & ChairmanBuy27,262Common Stock$4.75-$129,494.50  0.41     [ Average ]191,538,676$909,808,711.00  2,858.64 [Very High]Form 4See Footnote
2021-02-19Frost Phillip Md Et AlCEO & ChairmanBuy15,179Common Stock$4.75-$72,100.25  0.23     [ Low ]191,553,855$909,880,811.25  2,858.86 [Very High]Form 4See Footnote
2021-02-19Frost Phillip Md Et AlCEO & ChairmanBuy39,845Common Stock$4.76-$189,662.20  0.59     [ Average ]191,593,700$911,986,012.00  2,859.46 [Very High]Form 4See Footnote
2021-02-19Frost Phillip Md Et AlCEO & ChairmanBuy72,400Common Stock$4.77-$345,348.00  1.08     [ High ]191,666,100$914,247,297.00  2,860.54 [Very High]Form 4See Footnote
2021-02-19Frost Phillip Md Et AlCEO & ChairmanBuy528Common Stock$4.78-$2,523.84  -191,666,628$916,166,481.84  2,860.55 [Very High]Form 4See Footnote
2021-02-19Frost Phillip Md Et AlCEO & ChairmanBuy50,883Common Stock$4.78-$243,220.74  0.76     [ Average ]191,717,511$916,409,702.58  2,861.31 [Very High]Form 4See Footnote
2021-02-19Frost Phillip Md Et AlCEO & ChairmanBuy5,924Common Stock$4.79-$28,375.96  0.09     [ Very Low ]191,723,435$918,355,253.65  2,861.39 [Very High]Form 4See Footnote
2021-02-19Frost Phillip Md Et AlCEO & ChairmanBuy44,745Common Stock$4.79-$214,328.55  0.67     [ Average ]191,768,180$918,569,582.20  2,862.06 [Very High]Form 4See Footnote
2021-02-19Frost Phillip Md Et AlCEO & ChairmanBuy1,520Common Stock$4.79-$7,280.80  0.02     [ Very Low ]191,769,700$918,576,863.00  2,862.08 [Very High]Form 4See Footnote
2021-02-19Frost Phillip Md Et AlCEO & ChairmanBuy72,300Common Stock$4.80-$347,040.00  1.08     [ High ]191,842,000$920,841,600.00  2,863.16 [Very High]Form 4See Footnote
2021-02-19Frost Phillip Md Et AlCEO & ChairmanBuy892Common Stock$4.80-$4,281.60  -191,842,892$920,845,881.60  2,863.18 [Very High]Form 4See Footnote
2021-02-19Frost Phillip Md Et AlCEO & ChairmanBuy28,802Common Stock$4.81-$138,537.62  0.43     [ Average ]191,871,694$922,902,848.14  2,863.61 [Very High]Form 4See Footnote
2021-03-05Frost Phillip Md Et AlCEO & ChairmanBuy10Common Stock$3.85-$38.50  -191,871,704$738,706,060.40  2,863.61 [Very High]Form 4See Footnote
2021-03-05Frost Phillip Md Et AlCEO & ChairmanBuy11,900Common Stock$3.85-$45,815.00  0.18     [ Low ]191,883,604$738,751,875.40  2,863.78 [Very High]Form 4See Footnote
2021-03-05Frost Phillip Md Et AlCEO & ChairmanBuy7,675Common Stock$3.85-$29,548.75  0.11     [ Low ]191,891,279$738,781,424.15  2,863.90 [Very High]Form 4See Footnote
2021-03-05Frost Phillip Md Et AlCEO & ChairmanBuy3,760Common Stock$3.86-$14,513.60  0.06     [ Very Low ]191,895,039$740,714,850.54  2,863.96 [Very High]Form 4See Footnote
2021-03-05Frost Phillip Md Et AlCEO & ChairmanBuy18,000Common Stock$3.87-$69,660.00  0.27     [ Low ]191,913,039$742,703,460.93  2,864.22 [Very High]Form 4See Footnote
2021-03-05Frost Phillip Md Et AlCEO & ChairmanBuy200Common Stock$3.88-$776.00  -191,913,239$744,623,367.32  2,864.23 [Very High]Form 4See Footnote
2021-03-05Frost Phillip Md Et AlCEO & ChairmanBuy11,400Common Stock$3.88-$44,232.00  0.17     [ Low ]191,924,639$744,667,599.32  2,864.40 [Very High]Form 4See Footnote
2021-03-05Frost Phillip Md Et AlCEO & ChairmanBuy60,055Common Stock$3.88-$233,013.40  0.90     [ High ]191,984,694$744,900,612.72  2,865.29 [Very High]Form 4See Footnote
2021-03-05Frost Phillip Md Et AlCEO & ChairmanBuy500Common Stock$3.88-$1,940.00  -191,985,194$744,902,552.72  2,865.30 [Very High]Form 4See Footnote
2021-03-05Frost Phillip Md Et AlCEO & ChairmanBuy1,100Common Stock$3.89-$4,279.00  0.02     [ Very Low ]191,986,294$746,826,683.66  2,865.32 [Very High]Form 4See Footnote
2021-03-05Frost Phillip Md Et AlCEO & ChairmanBuy25,400Common Stock$3.89-$98,806.00  0.38     [ Average ]192,011,694$746,925,489.66  2,865.70 [Very High]Form 4See Footnote
2021-03-05Frost Phillip Md Et AlCEO & ChairmanBuy500Common Stock$3.90-$1,950.00  -192,012,194$748,847,556.60  2,865.70 [Very High]Form 4See Footnote
2021-03-05Frost Phillip Md Et AlCEO & ChairmanBuy1,160Common Stock$3.90-$4,524.00  0.02     [ Very Low ]192,013,354$748,852,080.60  2,865.72 [Very High]Form 4See Footnote
2021-03-05Frost Phillip Md Et AlCEO & ChairmanBuy18,340Common Stock$3.91-$71,709.40  0.27     [ Low ]192,031,694$750,843,923.54  2,865.99 [Very High]Form 4See Footnote
2021-03-05Frost Phillip Md Et AlCEO & ChairmanBuy14,000Common Stock$3.92-$54,880.00  0.21     [ Low ]192,045,694$752,819,120.48  2,866.20 [Very High]Form 4See Footnote
2021-03-05Frost Phillip Md Et AlCEO & ChairmanBuy27,059Common Stock$3.94-$106,612.46  0.40     [ Average ]192,072,753$756,766,646.82  2,866.61 [Very High]Form 4See Footnote
2021-03-05Frost Phillip Md Et AlCEO & ChairmanBuy200Common Stock$3.94-$788.00  -192,072,953$756,767,434.82  2,866.61 [Very High]Form 4See Footnote
2021-03-05Frost Phillip Md Et AlCEO & ChairmanBuy11,100Common Stock$3.95-$43,845.00  0.17     [ Low ]192,084,053$758,732,009.35  2,866.78 [Very High]Form 4See Footnote
2021-03-05Frost Phillip Md Et AlCEO & ChairmanBuy40,572Common Stock$3.95-$160,259.40  0.61     [ Average ]192,124,625$758,892,268.75  2,867.38 [Very High]Form 4See Footnote
2021-03-05Frost Phillip Md Et AlCEO & ChairmanBuy17,069Common Stock$3.96-$67,593.24  0.25     [ Low ]192,141,694$760,881,108.24  2,867.64 [Very High]Form 4See Footnote
2021-03-05Frost Phillip Md Et AlCEO & ChairmanBuy8,800Common Stock$3.97-$34,936.00  0.13     [ Low ]192,150,494$762,837,461.18  2,867.77 [Very High]Form 4See Footnote
2021-03-05Frost Phillip Md Et AlCEO & ChairmanBuy21,200Common Stock$3.97-$84,164.00  0.32     [ Average ]192,171,694$762,921,625.18  2,868.08 [Very High]Form 4See Footnote
2021-05-04Frost Phillip Md Et AlCEO & ChairmanBuy900Common Stock$3.92-$3,528.00  -192,172,594$753,316,568.48  2,867.59 [Very High]Form 4See Footnote
2021-05-04Frost Phillip Md Et AlCEO & ChairmanBuy1,000Common Stock$3.92-$3,920.00  -192,173,594$753,320,488.48  2,867.61 [Very High]Form 4See Footnote
2021-05-04Frost Phillip Md Et AlCEO & ChairmanBuy8,559Common Stock$3.92-$33,551.28  0.13     [ Low ]192,182,153$753,354,039.76  2,867.74 [Very High]Form 4See Footnote
2021-05-04Frost Phillip Md Et AlCEO & ChairmanBuy4,541Common Stock$3.94-$17,891.54  0.07     [ Very Low ]192,186,694$757,215,574.36  2,867.80 [Very High]Form 4See Footnote
2021-05-04Frost Phillip Md Et AlCEO & ChairmanBuy766Common Stock$3.96-$3,033.36  -192,187,460$761,062,341.60  2,867.81 [Very High]Form 4See Footnote
2021-05-04Frost Phillip Md Et AlCEO & ChairmanBuy9,234Common Stock$3.96-$36,566.64  0.14     [ Low ]192,196,694$761,098,908.24  2,867.95 [Very High]Form 4See Footnote
2021-05-06Frost Phillip Md Et AlCEO & ChairmanBuy1,000Common Stock$3.90-$3,900.00  -192,197,694$749,571,006.60  2,867.97 [Very High]Form 4See Footnote
2021-05-06Frost Phillip Md Et AlCEO & ChairmanBuy9,000Common Stock$3.90-$35,100.00  0.13     [ Low ]192,206,694$749,606,106.60  2,868.10 [Very High]Form 4See Footnote
2021-05-06Frost Phillip Md Et AlCEO & ChairmanBuy2,500Common Stock$3.92-$9,800.00  0.04     [ Very Low ]192,209,194$753,460,040.48  2,868.14 [Very High]Form 4See Footnote
2021-05-06Frost Phillip Md Et AlCEO & ChairmanBuy12,500Common Stock$3.92-$49,000.00  0.19     [ Low ]192,221,694$753,509,040.48  2,868.33 [Very High]Form 4See Footnote
2021-05-07Frost Phillip Md Et AlCEO & ChairmanBuy400Common Stock$3.81-$1,524.00  -192,222,094$732,366,178.14  2,868.33 [Very High]Form 4See Footnote
2021-05-07Frost Phillip Md Et AlCEO & ChairmanBuy3,800Common Stock$3.81-$14,478.00  0.06     [ Very Low ]192,225,894$732,380,656.14  2,868.39 [Very High]Form 4See Footnote
2021-05-07Frost Phillip Md Et AlCEO & ChairmanBuy20,800Common Stock$3.81-$79,248.00  0.31     [ Average ]192,246,694$732,459,904.14  2,868.70 [Very High]Form 4See Footnote
2021-05-07Frost Phillip Md Et AlCEO & ChairmanBuy200Common Stock$3.83-$766.00  -192,246,894$736,305,604.02  2,868.70 [Very High]Form 4See Footnote
2021-05-07Frost Phillip Md Et AlCEO & ChairmanBuy700Common Stock$3.83-$2,681.00  -192,247,594$736,308,285.02  2,868.71 [Very High]Form 4See Footnote
2021-05-07Frost Phillip Md Et AlCEO & ChairmanBuy24,100Common Stock$3.83-$92,303.00  0.36     [ Average ]192,271,694$736,400,588.02  2,869.07 [Very High]Form 4See Footnote
2021-05-07Frost Phillip Md Et AlCEO & ChairmanBuy25,000Common Stock$3.87-$96,750.00  0.37     [ Average ]192,296,694$744,188,205.78  2,869.44 [Very High]Form 4See Footnote
2021-05-10Frost Phillip Md Et AlCEO & ChairmanBuy1,000Common Stock$3.58-$3,580.00  -192,297,694$688,425,744.52  2,869.44 [Very High]Form 4See Footnote
2021-05-10Frost Phillip Md Et AlCEO & ChairmanBuy24,000Common Stock$3.58-$85,920.00  0.36     [ Average ]192,321,694$688,511,664.52  2,869.80 [Very High]Form 4See Footnote
2021-05-10Frost Phillip Md Et AlCEO & ChairmanBuy25,000Common Stock$3.63-$90,750.00  0.37     [ Average ]192,346,694$698,218,499.22  2,870.17 [Very High]Form 4See Footnote
2021-05-10Frost Phillip Md Et AlCEO & ChairmanBuy25,000Common Stock$3.74-$93,500.00  0.37     [ Average ]192,371,694$719,470,135.56  2,870.55 [Very High]Form 4See Footnote
2021-05-25Frost Phillip Md Et AlCEO & ChairmanBuy7,260Common Stock$3.62-$26,281.20  0.11     [ Low ]192,378,954$696,411,813.48  2,870.65 [Very High]Form 4See Footnote
2021-05-25Frost Phillip Md Et AlCEO & ChairmanBuy30,366Common Stock$3.63-$110,228.58  0.45     [ Average ]192,409,320$698,445,831.60  2,871.11 [Very High]Form 4See Footnote
2021-05-25Frost Phillip Md Et AlCEO & ChairmanBuy109,064Common Stock$3.63-$395,902.32  1.63     [ High ]192,518,384$698,841,733.92  2,872.74 [Very High]Form 4See Footnote
2021-05-25Frost Phillip Md Et AlCEO & ChairmanBuy13,200Common Stock$3.64-$48,048.00  0.20     [ Low ]192,531,584$700,814,965.76  2,872.93 [Very High]Form 4See Footnote
2021-05-25Frost Phillip Md Et AlCEO & ChairmanBuy114,631Common Stock$3.64-$417,256.84  1.71     [ High ]192,646,215$701,232,222.60  2,874.64 [Very High]Form 4See Footnote
2021-05-25Frost Phillip Md Et AlCEO & ChairmanBuy62,273Common Stock$3.65-$227,296.45  0.93     [ High ]192,708,488$703,385,981.20  2,875.57 [Very High]Form 4See Footnote
2021-05-25Frost Phillip Md Et AlCEO & ChairmanBuy63,206Common Stock$3.65-$230,701.90  0.94     [ High ]192,771,694$703,616,683.10  2,876.52 [Very High]Form 4See Footnote
2021-05-10Jon R CohenSVP OPKO; Exec Chairman BRLIBuy50,000Common Stock$3.81-$190,500.00  0.75     [ Average ]125,000$476,250.00  1.87     [Low]Form 4-
2021-06-14Frost Phillip Md Et AlCEO & ChairmanBuy3,500Common Stock$3.60-$12,600.00  0.05     [ Very Low ]192,775,194$693,990,698.40  2,876.57 [Very High]Form 4See Footnote
2021-06-14Frost Phillip Md Et AlCEO & ChairmanBuy40,325Common Stock$3.60-$145,170.00  0.60     [ Average ]192,815,519$694,135,868.40  2,877.17 [Very High]Form 4See Footnote
2021-06-14Frost Phillip Md Et AlCEO & ChairmanBuy3,500Common Stock$3.61-$12,635.00  0.05     [ Very Low ]192,819,019$696,076,658.59  2,877.22 [Very High]Form 4See Footnote
2021-06-14Frost Phillip Md Et AlCEO & ChairmanBuy22,592Common Stock$3.61-$81,557.12  0.34     [ Average ]192,841,611$696,158,215.71  2,877.56 [Very High]Form 4See Footnote
2021-06-14Frost Phillip Md Et AlCEO & ChairmanBuy39,038Common Stock$3.62-$141,317.56  0.58     [ Average ]192,880,649$698,227,949.38  2,878.14 [Very High]Form 4See Footnote
2021-06-14Frost Phillip Md Et AlCEO & ChairmanBuy12,432Common Stock$3.62-$45,003.84  0.19     [ Low ]192,893,081$698,272,953.22  2,878.33 [Very High]Form 4See Footnote
2021-06-14Frost Phillip Md Et AlCEO & ChairmanBuy3,008Common Stock$3.62-$10,888.96  0.04     [ Very Low ]192,896,089$698,283,842.18  2,878.37 [Very High]Form 4See Footnote
2021-06-14Frost Phillip Md Et AlCEO & ChairmanBuy22,711Common Stock$3.63-$82,440.93  0.34     [ Average ]192,918,800$700,295,244.00  2,878.71 [Very High]Form 4See Footnote
2021-06-14Frost Phillip Md Et AlCEO & ChairmanBuy3,900Common Stock$3.63-$14,157.00  0.06     [ Very Low ]192,922,700$700,309,401.00  2,878.77 [Very High]Form 4See Footnote
2021-06-14Frost Phillip Md Et AlCEO & ChairmanBuy48,994Common Stock$3.64-$178,338.16  0.73     [ Average ]192,971,694$702,416,966.16  2,879.50 [Very High]Form 4See Footnote
2021-08-09Hsiao Jane Ph DVice Chairman & CTOBuy10Common Stock$3.73-$37.30  -27,599,870$102,947,515.10  405.19   [Very High]Form 4-
2021-08-13Frost Phillip Md Et AlCEO & ChairmanBuy4,518Common Stock$3.67-$16,581.06  0.07     [ Very Low ]192,976,212$708,222,698.04  2,833.04 [Very High]Form 4See Footnote
2021-08-13Frost Phillip Md Et AlCEO & ChairmanBuy13,682Common Stock$3.68-$50,349.76  0.20     [ Low ]192,989,894$710,202,809.92  2,833.24 [Very High]Form 4See Footnote
2021-08-13Frost Phillip Md Et AlCEO & ChairmanBuy5,108Common Stock$3.69-$18,848.52  0.07     [ Very Low ]192,995,002$712,151,557.38  2,833.32 [Very High]Form 4See Footnote
2021-08-13Frost Phillip Md Et AlCEO & ChairmanBuy2,292Common Stock$3.69-$8,457.48  0.03     [ Very Low ]192,997,294$712,160,014.86  2,833.35 [Very High]Form 4See Footnote
2021-08-13Frost Phillip Md Et AlCEO & ChairmanBuy53,873Common Stock$3.69-$198,791.37  0.79     [ High ]193,051,167$712,358,806.23  2,834.14 [Very High]Form 4See Footnote
2021-08-13Frost Phillip Md Et AlCEO & ChairmanBuy500Common Stock$3.69-$1,845.00  -193,051,667$712,360,651.23  2,834.15 [Very High]Form 4See Footnote
2021-08-13Frost Phillip Md Et AlCEO & ChairmanBuy17,988Common Stock$3.70-$66,555.60  0.26     [ Low ]193,069,655$714,357,723.50  2,834.41 [Very High]Form 4See Footnote
2021-08-13Frost Phillip Md Et AlCEO & ChairmanBuy700Common Stock$3.71-$2,597.00  -193,070,355$716,291,017.05  2,834.42 [Very High]Form 4See Footnote
2021-08-13Frost Phillip Md Et AlCEO & ChairmanBuy1,339Common Stock$3.71-$4,967.69  0.02     [ Very Low ]193,071,694$716,295,984.74  2,834.44 [Very High]Form 4See Footnote
2021-09-14Frost Phillip Md Et AlCEO & ChairmanBuy500Common Stock$3.44-$1,720.00  -193,072,194$664,168,347.36  2,834.45 [Very High]Form 4See Footnote
2021-09-14Frost Phillip Md Et AlCEO & ChairmanBuy5,825Common Stock$3.45-$20,096.25  0.09     [ Very Low ]193,078,019$666,119,165.55  2,834.53 [Very High]Form 4See Footnote
2021-09-14Frost Phillip Md Et AlCEO & ChairmanBuy21,905Common Stock$3.45-$75,572.25  0.32     [ Average ]193,099,924$666,194,737.80  2,834.86 [Very High]Form 4See Footnote
2021-09-14Frost Phillip Md Et AlCEO & ChairmanBuy10,100Common Stock$3.46-$34,946.00  0.15     [ Low ]193,110,024$668,160,683.04  2,835.00 [Very High]Form 4See Footnote
2021-09-14Frost Phillip Md Et AlCEO & ChairmanBuy400Common Stock$3.46-$1,384.00  -193,110,424$668,162,067.04  2,835.01 [Very High]Form 4See Footnote
2021-09-14Frost Phillip Md Et AlCEO & ChairmanBuy44,085Common Stock$3.47-$152,974.95  0.65     [ Average ]193,154,509$670,246,146.23  2,835.66 [Very High]Form 4See Footnote
2021-09-14Frost Phillip Md Et AlCEO & ChairmanBuy400Common Stock$3.48-$1,392.00  -193,154,909$672,179,083.32  2,835.66 [Very High]Form 4See Footnote
2021-09-14Frost Phillip Md Et AlCEO & ChairmanBuy16,785Common Stock$3.48-$58,411.80  0.25     [ Low ]193,171,694$672,237,495.12  2,835.91 [Very High]Form 4See Footnote
2022-01-26Frost Phillip Md Et AlCEO & ChairmanBuy900Common Stock$2.92-$2,628.00  -193,172,594$564,063,974.48  2,835.18 [Very High]Form 4See Footnote
2022-01-26Frost Phillip Md Et AlCEO & ChairmanBuy12,100Common Stock$2.92-$35,332.00  0.18     [ Low ]193,184,694$564,099,306.48  2,835.36 [Very High]Form 4See Footnote
2022-01-26Frost Phillip Md Et AlCEO & ChairmanBuy27,357Common Stock$2.92-$79,882.44  0.40     [ Average ]193,212,051$564,179,188.92  2,835.76 [Very High]Form 4See Footnote
2022-01-26Frost Phillip Md Et AlCEO & ChairmanBuy600Common Stock$2.92-$1,752.00  -193,212,651$564,180,940.92  2,835.77 [Very High]Form 4See Footnote
2022-01-26Frost Phillip Md Et AlCEO & ChairmanBuy34,043Common Stock$2.93-$99,745.99  0.50     [ Average ]193,246,694$566,212,813.42  2,836.27 [Very High]Form 4See Footnote
2022-01-26Frost Phillip Md Et AlCEO & ChairmanBuy20,000Common Stock$2.96-$59,200.00  0.29     [ Average ]193,266,694$572,069,414.24  2,836.56 [Very High]Form 4See Footnote
2022-01-26Frost Phillip Md Et AlCEO & ChairmanBuy20,600Common Stock$2.97-$61,182.00  0.30     [ Average ]193,287,294$574,063,263.18  2,836.87 [Very High]Form 4See Footnote
2022-01-26Frost Phillip Md Et AlCEO & ChairmanBuy14,800Common Stock$2.98-$44,104.00  0.22     [ Low ]193,302,094$576,040,240.12  2,837.08 [Very High]Form 4See Footnote
2022-01-26Frost Phillip Md Et AlCEO & ChairmanBuy10,300Common Stock$2.98-$30,694.00  0.15     [ Low ]193,312,394$576,070,934.12  2,837.23 [Very High]Form 4See Footnote
2022-01-26Frost Phillip Md Et AlCEO & ChairmanBuy11,300Common Stock$2.98-$33,674.00  0.17     [ Low ]193,323,694$576,104,608.12  2,837.40 [Very High]Form 4See Footnote
2022-01-26Frost Phillip Md Et AlCEO & ChairmanBuy16,600Common Stock$2.99-$49,634.00  0.24     [ Low ]193,340,294$578,087,479.06  2,837.64 [Very High]Form 4See Footnote
2022-01-26Frost Phillip Md Et AlCEO & ChairmanBuy5,000Common Stock$2.99-$14,950.00  0.07     [ Very Low ]193,345,294$578,102,429.06  2,837.72 [Very High]Form 4See Footnote
2022-01-26Frost Phillip Md Et AlCEO & ChairmanBuy50,874Common Stock$2.99-$152,113.26  0.75     [ Average ]193,396,168$578,254,542.32  2,838.46 [Very High]Form 4See Footnote
2022-01-26Frost Phillip Md Et AlCEO & ChairmanBuy200Common Stock$3.00-$600.00  -193,396,368$580,189,104.00  2,838.47 [Very High]Form 4See Footnote
2022-01-26Frost Phillip Md Et AlCEO & ChairmanBuy85,326Common Stock$3.00-$255,978.00  1.25     [ High ]193,481,694$580,445,082.00  2,839.72 [Very High]Form 4See Footnote
2022-01-26Frost Phillip Md Et AlCEO & ChairmanBuy100Common Stock$3.00-$300.00  -193,481,794$580,445,382.00  2,839.72 [Very High]Form 4See Footnote
2022-01-26Frost Phillip Md Et AlCEO & ChairmanBuy39,900Common Stock$3.01-$120,099.00  0.59     [ Average ]193,521,694$582,500,298.94  2,840.31 [Very High]Form 4See Footnote
2022-02-01Frost Phillip Md Et AlCEO & ChairmanBuy1,200Common Stock$3.00-$3,600.00  0.02     [ Very Low ]193,522,894$580,568,682.00  2,840.32 [Very High]Form 4See Footnote
2022-02-01Frost Phillip Md Et AlCEO & ChairmanBuy18,800Common Stock$3.00-$56,400.00  0.28     [ Average ]193,541,694$580,625,082.00  2,840.60 [Very High]Form 4See Footnote
2022-02-01Frost Phillip Md Et AlCEO & ChairmanBuy12,000Common Stock$3.02-$36,240.00  0.18     [ Low ]193,553,694$584,532,155.88  2,840.78 [Very High]Form 4See Footnote
2022-02-01Frost Phillip Md Et AlCEO & ChairmanBuy19,200Common Stock$3.03-$58,176.00  0.28     [ Average ]193,572,894$586,525,868.82  2,841.06 [Very High]Form 4See Footnote
2022-02-01Frost Phillip Md Et AlCEO & ChairmanBuy6,300Common Stock$3.03-$19,089.00  0.09     [ Very Low ]193,579,194$586,544,957.82  2,841.15 [Very High]Form 4See Footnote
2022-02-01Frost Phillip Md Et AlCEO & ChairmanBuy20,600Common Stock$3.04-$62,624.00  0.30     [ Average ]193,599,794$588,543,373.76  2,841.45 [Very High]Form 4See Footnote
2022-02-01Frost Phillip Md Et AlCEO & ChairmanBuy9,900Common Stock$3.04-$30,096.00  0.15     [ Low ]193,609,694$588,573,469.76  2,841.60 [Very High]Form 4See Footnote
2022-02-01Frost Phillip Md Et AlCEO & ChairmanBuy44,500Common Stock$3.04-$135,280.00  0.65     [ Average ]193,654,194$588,708,749.76  2,842.25 [Very High]Form 4See Footnote
2022-02-01Frost Phillip Md Et AlCEO & ChairmanBuy17,500Common Stock$3.05-$53,375.00  0.26     [ Low ]193,671,694$590,698,666.70  2,842.51 [Very High]Form 4See Footnote
2022-02-14Frost Phillip Md Et AlCEO & ChairmanBuy13,273Common Stock$3.02-$40,084.46  0.19     [ Low ]193,684,967$584,928,600.34  2,842.70 [Very High]Form 4See Footnote
2022-02-14Frost Phillip Md Et AlCEO & ChairmanBuy1,259Common Stock$3.02-$3,802.18  0.02     [ Very Low ]193,686,226$584,932,402.52  2,842.72 [Very High]Form 4See Footnote
2022-02-14Frost Phillip Md Et AlCEO & ChairmanBuy608Common Stock$3.02-$1,836.16  -193,686,834$584,934,238.68  2,842.73 [Very High]Form 4See Footnote
2022-02-14Frost Phillip Md Et AlCEO & ChairmanBuy1,701Common Stock$3.03-$5,154.03  0.02     [ Very Low ]193,688,535$586,876,261.05  2,842.75 [Very High]Form 4See Footnote
2022-02-14Frost Phillip Md Et AlCEO & ChairmanBuy28,759Common Stock$3.03-$87,139.77  0.42     [ Average ]193,717,294$586,963,400.82  2,843.18 [Very High]Form 4See Footnote
2022-02-14Frost Phillip Md Et AlCEO & ChairmanBuy11,809Common Stock$3.04-$35,899.36  0.17     [ Low ]193,729,103$588,936,473.12  2,843.35 [Very High]Form 4See Footnote
2022-02-14Frost Phillip Md Et AlCEO & ChairmanBuy18,191Common Stock$3.04-$55,300.64  0.27     [ Low ]193,747,294$588,991,773.76  2,843.62 [Very High]Form 4See Footnote
2022-02-14Frost Phillip Md Et AlCEO & ChairmanBuy8,200Common Stock$3.04-$24,928.00  0.12     [ Low ]193,755,494$589,016,701.76  2,843.74 [Very High]Form 4See Footnote
2022-02-14Frost Phillip Md Et AlCEO & ChairmanBuy300Common Stock$3.05-$915.00  -193,755,794$590,955,171.70  2,843.74 [Very High]Form 4See Footnote
2022-02-14Frost Phillip Md Et AlCEO & ChairmanBuy12,400Common Stock$3.06-$37,944.00  0.18     [ Low ]193,768,194$592,930,673.64  2,843.92 [Very High]Form 4See Footnote
2022-02-14Frost Phillip Md Et AlCEO & ChairmanBuy3,500Common Stock$3.06-$10,710.00  0.05     [ Very Low ]193,771,694$592,941,383.64  2,843.98 [Very High]Form 4See Footnote
2022-02-25Frost Phillip Md Et AlCEO & ChairmanBuy750,000Common Stock$3.09-$2,317,500.00  11.01    [ Very High ]194,521,694$601,072,034.46  2,854.98 [Very High]Form 4See Footnote
2022-03-11Frost Phillip Md Et AlCEO & ChairmanBuy100Common Stock$3.12-$312.00  -194,621,794$607,219,997.28  2,855.97 [Very High]Form 4See Footnote
2022-03-11Frost Phillip Md Et AlCEO & ChairmanBuy26,863Common Stock$3.12-$83,812.56  0.39     [ Average ]194,648,657$607,303,809.84  2,856.37 [Very High]Form 4See Footnote
2022-03-11Frost Phillip Md Et AlCEO & ChairmanBuy73,037Common Stock$3.13-$228,605.81  1.07     [ High ]194,721,694$609,478,902.22  2,857.44 [Very High]Form 4See Footnote
2022-03-14Frost Phillip Md Et AlCEO & ChairmanBuy9,955Common Stock$3.02-$30,064.10  0.15     [ Low ]194,731,649$588,089,579.98  2,857.59 [Very High]Form 4See Footnote
2022-03-14Frost Phillip Md Et AlCEO & ChairmanBuy9,200Common Stock$3.03-$27,876.00  0.14     [ Low ]194,740,849$590,064,772.47  2,857.72 [Very High]Form 4See Footnote
2022-03-14Frost Phillip Md Et AlCEO & ChairmanBuy15,845Common Stock$3.05-$48,327.25  0.23     [ Low ]194,756,694$594,007,916.70  2,857.95 [Very High]Form 4See Footnote
2022-05-09Alexis Borisy-Buy312,612Common Stock$0.00$0.00  -312,612$0.00  4.59     [Low]Form 4-
2022-05-10Frost Phillip Md Et AlCEO & ChairmanBuy400,000Common Stock$2.78-$1,112,000.00  5.87     [ Very High ]195,156,694$542,535,609.32  2,863.53 [Very High]Form 4See Footnote
2022-05-10Elias A. ZerhouniVice Chairman and PresidentBuy89,600Common Stock$2.79-$249,984.00  1.31     [ High ]89,600$249,984.00  1.31     [Low]Form 4-
2022-05-11Frost Phillip Md Et AlCEO & ChairmanBuy400,000Common Stock$2.83-$1,132,000.00  5.87     [ Very High ]195,556,694$553,425,444.02  2,869.40 [Very High]Form 4See Footnote
2022-05-13Frost Phillip Md Et AlCEO & ChairmanBuy1,100Common Stock$2.95-$3,245.00  0.02     [ Very Low ]195,557,794$576,895,492.30  2,869.41 [Very High]Form 4See Footnote
2022-05-13Frost Phillip Md Et AlCEO & ChairmanBuy3,800Common Stock$2.96-$11,248.00  0.06     [ Very Low ]195,561,594$578,862,318.24  2,869.47 [Very High]Form 4See Footnote
2022-05-13Frost Phillip Md Et AlCEO & ChairmanBuy8,500Common Stock$2.96-$25,160.00  0.12     [ Low ]195,570,094$578,887,478.24  2,869.60 [Very High]Form 4See Footnote
2022-05-13Frost Phillip Md Et AlCEO & ChairmanBuy900Common Stock$2.96-$2,664.00  -195,570,994$578,890,142.24  2,869.61 [Very High]Form 4See Footnote
2022-05-13Frost Phillip Md Et AlCEO & ChairmanBuy600Common Stock$2.97-$1,782.00  -195,571,594$580,847,634.18  2,869.62 [Very High]Form 4See Footnote
2022-05-13Frost Phillip Md Et AlCEO & ChairmanBuy17,080Common Stock$2.98-$50,898.40  0.25     [ Low ]195,588,674$582,854,248.52  2,869.87 [Very High]Form 4See Footnote
2022-05-13Frost Phillip Md Et AlCEO & ChairmanBuy31,420Common Stock$2.98-$93,631.60  0.46     [ Average ]195,620,094$582,947,880.12  2,870.33 [Very High]Form 4See Footnote
2022-05-13Frost Phillip Md Et AlCEO & ChairmanBuy12,975Common Stock$2.98-$38,665.50  0.19     [ Low ]195,633,069$582,986,545.62  2,870.52 [Very High]Form 4See Footnote
2022-05-13Frost Phillip Md Et AlCEO & ChairmanBuy27,600Common Stock$2.99-$82,524.00  0.40     [ Average ]195,660,669$585,025,400.31  2,870.92 [Very High]Form 4See Footnote
2022-05-13Frost Phillip Md Et AlCEO & ChairmanBuy11,630Common Stock$3.00-$34,890.00  0.17     [ Low ]195,672,299$587,016,897.00  2,871.09 [Very High]Form 4See Footnote
2022-05-13Frost Phillip Md Et AlCEO & ChairmanBuy7,370Common Stock$3.00-$22,110.00  0.11     [ Low ]195,679,669$587,039,007.00  2,871.20 [Very High]Form 4See Footnote
2022-05-13Frost Phillip Md Et AlCEO & ChairmanBuy7,223Common Stock$3.00-$21,669.00  0.11     [ Low ]195,686,892$587,060,676.00  2,871.31 [Very High]Form 4See Footnote
2022-05-13Frost Phillip Md Et AlCEO & ChairmanBuy19,902Common Stock$3.01-$59,905.02  0.29     [ Average ]195,706,794$589,077,449.94  2,871.60 [Very High]Form 4See Footnote
2022-05-13Frost Phillip Md Et AlCEO & ChairmanBuy3,577Common Stock$3.02-$10,802.54  0.05     [ Very Low ]195,710,371$591,045,320.42  2,871.65 [Very High]Form 4See Footnote
2022-05-13Frost Phillip Md Et AlCEO & ChairmanBuy12,700Common Stock$3.02-$38,354.00  0.19     [ Low ]195,723,071$591,083,674.42  2,871.84 [Very High]Form 4See Footnote
2022-05-13Frost Phillip Md Et AlCEO & ChairmanBuy14,023Common Stock$3.02-$42,349.46  0.21     [ Low ]195,737,094$591,126,023.88  2,872.05 [Very High]Form 4See Footnote
2022-05-13Frost Phillip Md Et AlCEO & ChairmanBuy13,200Common Stock$3.03-$39,996.00  0.19     [ Low ]195,750,294$593,123,390.82  2,872.24 [Very High]Form 4See Footnote
2022-05-13Frost Phillip Md Et AlCEO & ChairmanBuy6,000Common Stock$3.04-$18,240.00  0.09     [ Low ]195,756,294$595,099,133.76  2,872.33 [Very High]Form 4See Footnote
2022-05-13Frost Phillip Md Et AlCEO & ChairmanBuy400Common Stock$3.04-$1,216.00  -195,756,694$595,100,349.76  2,872.33 [Very High]Form 4See Footnote
2022-05-16Frost Phillip Md Et AlCEO & ChairmanBuy660Common Stock$2.96-$1,953.60  -195,757,354$579,441,767.84  2,872.34 [Very High]Form 4See Footnote
2022-05-16Frost Phillip Md Et AlCEO & ChairmanBuy18,282Common Stock$2.96-$54,114.72  0.27     [ Average ]195,775,636$579,495,882.56  2,872.61 [Very High]Form 4See Footnote
2022-05-16Frost Phillip Md Et AlCEO & ChairmanBuy3,300Common Stock$2.96-$9,768.00  0.05     [ Very Low ]195,778,936$579,505,650.56  2,872.66 [Very High]Form 4See Footnote
2022-05-16Frost Phillip Md Et AlCEO & ChairmanBuy11,358Common Stock$2.97-$33,733.26  0.17     [ Low ]195,790,294$581,497,173.18  2,872.83 [Very High]Form 4See Footnote
2022-05-16Frost Phillip Md Et AlCEO & ChairmanBuy38,500Common Stock$2.98-$114,730.00  0.56     [ Average ]195,828,794$583,569,806.12  2,873.39 [Very High]Form 4See Footnote
2022-05-16Frost Phillip Md Et AlCEO & ChairmanBuy4,100Common Stock$2.98-$12,218.00  0.06     [ Very Low ]195,832,894$583,582,024.12  2,873.45 [Very High]Form 4See Footnote
2022-05-16Frost Phillip Md Et AlCEO & ChairmanBuy42,177Common Stock$2.98-$125,687.46  0.62     [ Average ]195,875,071$583,707,711.58  2,874.07 [Very High]Form 4See Footnote
2022-05-16Frost Phillip Md Et AlCEO & ChairmanBuy30,723Common Stock$2.99-$91,861.77  0.45     [ Average ]195,905,794$585,758,324.06  2,874.52 [Very High]Form 4See Footnote
2022-05-16Frost Phillip Md Et AlCEO & ChairmanBuy900Common Stock$3.00-$2,700.00  -195,906,694$587,720,082.00  2,874.53 [Very High]Form 4See Footnote
2022-05-25Frost Phillip Md Et AlCEO & ChairmanBuy12,852Common Stock$2.96-$38,041.92  0.19     [ Low ]195,969,546$580,069,856.16  2,875.46 [Very High]Form 4See Footnote
2022-05-25Frost Phillip Md Et AlCEO & ChairmanBuy6,000Common Stock$2.96-$17,760.00  0.09     [ Low ]195,975,546$580,087,616.16  2,875.54 [Very High]Form 4See Footnote
2022-05-25Frost Phillip Md Et AlCEO & ChairmanBuy15,190Common Stock$2.98-$45,266.20  0.22     [ Low ]195,990,736$584,052,393.28  2,875.77 [Very High]Form 4See Footnote
2022-05-25Frost Phillip Md Et AlCEO & ChairmanBuy800Common Stock$2.98-$2,384.00  -195,991,536$584,054,777.28  2,875.78 [Very High]Form 4See Footnote
2022-05-25Frost Phillip Md Et AlCEO & ChairmanBuy4,782Common Stock$3.00-$14,346.00  0.07     [ Very Low ]195,996,318$587,988,954.00  2,875.85 [Very High]Form 4See Footnote
2022-05-25Frost Phillip Md Et AlCEO & ChairmanBuy10,376Common Stock$3.01-$31,231.76  0.15     [ Low ]196,006,694$589,980,148.94  2,876.00 [Very High]Form 4See Footnote
2022-05-31Frost Phillip Md Et AlCEO & ChairmanBuy500Common Stock$3.00-$1,500.00  -196,007,194$588,021,582.00  2,876.01 [Very High]Form 4See Footnote
2022-05-31Frost Phillip Md Et AlCEO & ChairmanBuy12,200Common Stock$3.00-$36,600.00  0.18     [ Low ]196,019,394$588,058,182.00  2,876.19 [Very High]Form 4See Footnote
2022-05-31Frost Phillip Md Et AlCEO & ChairmanBuy1,900Common Stock$3.02-$5,738.00  0.03     [ Very Low ]196,021,294$591,984,307.88  2,876.22 [Very High]Form 4See Footnote
2022-05-31Frost Phillip Md Et AlCEO & ChairmanBuy5,031Common Stock$3.02-$15,193.62  0.07     [ Very Low ]196,026,325$591,999,501.50  2,876.29 [Very High]Form 4See Footnote
2022-05-31Frost Phillip Md Et AlCEO & ChairmanBuy8,130Common Stock$3.02-$24,552.60  0.12     [ Low ]196,034,455$592,024,054.10  2,876.41 [Very High]Form 4See Footnote
2022-05-31Frost Phillip Md Et AlCEO & ChairmanBuy8,181Common Stock$3.03-$24,788.43  0.12     [ Low ]196,042,636$594,009,187.08  2,876.53 [Very High]Form 4See Footnote
2022-05-31Frost Phillip Md Et AlCEO & ChairmanBuy6,958Common Stock$3.04-$21,152.32  0.10     [ Low ]196,049,594$595,990,765.76  2,876.63 [Very High]Form 4See Footnote
2022-05-31Frost Phillip Md Et AlCEO & ChairmanBuy5,400Common Stock$3.04-$16,416.00  0.08     [ Very Low ]196,054,994$596,007,181.76  2,876.71 [Very High]Form 4See Footnote
2022-05-31Frost Phillip Md Et AlCEO & ChairmanBuy1,200Common Stock$3.04-$3,648.00  0.02     [ Very Low ]196,056,194$596,010,829.76  2,876.73 [Very High]Form 4See Footnote
2022-05-31Frost Phillip Md Et AlCEO & ChairmanBuy500Common Stock$3.05-$1,525.00  -196,056,694$597,972,916.70  2,876.74 [Very High]Form 4See Footnote
2022-06-01Frost Phillip Md Et AlCEO & ChairmanBuy5,000Common Stock$2.93-$14,650.00  0.07     [ Very Low ]196,061,694$574,460,763.42  2,876.81 [Very High]Form 4See Footnote
2022-06-01Frost Phillip Md Et AlCEO & ChairmanBuy20,000Common Stock$2.94-$58,800.00  0.29     [ Average ]196,081,694$576,480,180.36  2,877.10 [Very High]Form 4See Footnote
2022-06-01Frost Phillip Md Et AlCEO & ChairmanBuy5,000Common Stock$2.95-$14,750.00  0.07     [ Very Low ]196,086,694$578,455,747.30  2,877.18 [Very High]Form 4See Footnote
2022-06-01Frost Phillip Md Et AlCEO & ChairmanBuy500Common Stock$2.96-$1,480.00  -196,087,194$580,418,094.24  2,877.18 [Very High]Form 4See Footnote
2022-06-01Frost Phillip Md Et AlCEO & ChairmanBuy14,900Common Stock$2.96-$44,104.00  0.22     [ Low ]196,102,094$580,462,198.24  2,877.40 [Very High]Form 4See Footnote
2022-06-01Frost Phillip Md Et AlCEO & ChairmanBuy500Common Stock$2.98-$1,490.00  -196,102,594$584,385,730.12  2,877.41 [Very High]Form 4See Footnote
2022-06-01Frost Phillip Md Et AlCEO & ChairmanBuy3,800Common Stock$3.02-$11,476.00  0.06     [ Very Low ]196,106,394$592,241,309.88  2,877.46 [Very High]Form 4See Footnote
2022-06-01Frost Phillip Md Et AlCEO & ChairmanBuy300Common Stock$3.02-$906.00  -196,106,694$592,242,215.88  2,877.47 [Very High]Form 4See Footnote
2022-06-06Frost Phillip Md Et AlCEO & ChairmanBuy50,000Common Stock$2.77-$138,500.00  0.73     [ Average ]196,156,694$543,354,042.38  2,878.20 [Very High]Form 4See Footnote
2022-06-06Frost Phillip Md Et AlCEO & ChairmanBuy1,062Common Stock$2.81-$2,984.22  0.02     [ Very Low ]196,157,756$551,203,294.36  2,878.22 [Very High]Form 4See Footnote
2022-06-06Frost Phillip Md Et AlCEO & ChairmanBuy2,237Common Stock$2.81-$6,285.97  0.03     [ Very Low ]196,159,993$551,209,580.33  2,878.25 [Very High]Form 4See Footnote
2022-06-06Frost Phillip Md Et AlCEO & ChairmanBuy600Common Stock$2.81-$1,686.00  -196,160,593$551,211,266.33  2,878.26 [Very High]Form 4See Footnote
2022-06-06Frost Phillip Md Et AlCEO & ChairmanBuy46,101Common Stock$2.81-$129,543.81  0.68     [ Average ]196,206,694$551,340,810.14  2,878.94 [Very High]Form 4See Footnote
2022-06-13Frost Phillip Md Et AlCEO & ChairmanBuy700Common Stock$2.36-$1,652.00  -196,207,394$463,049,449.84  2,878.95 [Very High]Form 4See Footnote
2022-06-13Frost Phillip Md Et AlCEO & ChairmanBuy99,300Common Stock$2.37-$235,341.00  1.46     [ High ]196,306,694$465,246,864.78  2,880.40 [Very High]Form 4See Footnote
2022-06-16Frost Phillip Md Et AlCEO & ChairmanBuy9,560Common Stock$2.29-$21,892.40  0.14     [ Low ]196,316,254$449,564,221.66  2,880.54 [Very High]Form 4See Footnote
2022-06-16Frost Phillip Md Et AlCEO & ChairmanBuy15,866Common Stock$2.29-$36,333.14  0.23     [ Low ]196,332,120$449,600,554.80  2,880.78 [Very High]Form 4See Footnote
2022-06-16Frost Phillip Md Et AlCEO & ChairmanBuy4,804Common Stock$2.29-$11,001.16  0.07     [ Very Low ]196,336,924$449,611,555.96  2,880.85 [Very High]Form 4See Footnote
2022-06-16Frost Phillip Md Et AlCEO & ChairmanBuy3Common Stock$2.30-$6.90  -196,336,927$451,574,932.10  2,880.85 [Very High]Form 4See Footnote
2022-06-16Frost Phillip Md Et AlCEO & ChairmanBuy1,429Common Stock$2.31-$3,300.99  0.02     [ Very Low ]196,338,356$453,541,602.36  2,880.87 [Very High]Form 4See Footnote
2022-06-16Frost Phillip Md Et AlCEO & ChairmanBuy10,724Common Stock$2.31-$24,772.44  0.16     [ Low ]196,349,080$453,566,374.80  2,881.03 [Very High]Form 4See Footnote
2022-06-16Frost Phillip Md Et AlCEO & ChairmanBuy14,549Common Stock$2.31-$33,608.19  0.21     [ Low ]196,363,629$453,599,982.99  2,881.24 [Very High]Form 4See Footnote
2022-06-16Frost Phillip Md Et AlCEO & ChairmanBuy28,614Common Stock$2.33-$66,670.62  0.42     [ Average ]196,392,243$457,593,926.19  2,881.66 [Very High]Form 4See Footnote
2022-06-16Frost Phillip Md Et AlCEO & ChairmanBuy300Common Stock$2.33-$699.00  -196,392,543$457,594,625.19  2,881.66 [Very High]Form 4See Footnote
2022-06-16Frost Phillip Md Et AlCEO & ChairmanBuy100Common Stock$2.33-$233.00  -196,392,643$457,594,858.19  2,881.66 [Very High]Form 4See Footnote
2022-06-16Frost Phillip Md Et AlCEO & ChairmanBuy4,100Common Stock$2.33-$9,553.00  0.06     [ Very Low ]196,396,743$457,604,411.19  2,881.72 [Very High]Form 4See Footnote
2022-06-16Frost Phillip Md Et AlCEO & ChairmanBuy9,551Common Stock$2.35-$22,444.85  0.14     [ Low ]196,406,294$461,554,790.90  2,881.86 [Very High]Form 4See Footnote
2022-06-16Frost Phillip Md Et AlCEO & ChairmanBuy400Common Stock$2.35-$940.00  -196,406,694$461,555,730.90  2,881.87 [Very High]Form 4See Footnote
2022-06-21Frost Phillip Md Et AlCEO & ChairmanBuy29,715Common Stock$2.38-$70,721.70  0.44     [ Average ]196,436,409$467,518,653.42  2,882.31 [Very High]Form 4See Footnote
2022-06-21Frost Phillip Md Et AlCEO & ChairmanBuy4,000Common Stock$2.39-$9,560.00  0.06     [ Very Low ]196,440,409$469,492,577.51  2,882.37 [Very High]Form 4See Footnote
2022-06-21Frost Phillip Md Et AlCEO & ChairmanBuy49,778Common Stock$2.39-$118,969.42  0.73     [ Average ]196,490,187$469,611,546.93  2,883.10 [Very High]Form 4See Footnote
2022-06-21Frost Phillip Md Et AlCEO & ChairmanBuy40,009Common Stock$2.40-$96,021.60  0.59     [ Average ]196,530,196$471,672,470.40  2,883.68 [Very High]Form 4See Footnote
2022-06-21Frost Phillip Md Et AlCEO & ChairmanBuy68,340Common Stock$2.40-$164,016.00  1.00     [ High ]196,598,536$471,836,486.40  2,884.69 [Very High]Form 4See Footnote
2022-06-21Frost Phillip Md Et AlCEO & ChairmanBuy7,466Common Stock$2.40-$17,918.40  0.11     [ Low ]196,606,002$471,854,404.80  2,884.80 [Very High]Form 4See Footnote
2022-06-21Frost Phillip Md Et AlCEO & ChairmanBuy692Common Stock$2.41-$1,667.72  -196,606,694$473,822,132.54  2,884.81 [Very High]Form 4See Footnote
2022-06-22Gary J. NabelChief Innovation OfficerBuy1,491Common Stock$2.50-$3,727.50  0.02     [ Very Low ]19,779,005$49,447,512.50  290.22   [Very High]Form 4Held by the GJN 2021 TRUST
2022-06-22Gary J. NabelChief Innovation OfficerBuy65,280Common Stock$2.50-$163,200.00  0.96     [ High ]19,844,285$49,610,712.50  291.17   [Very High]Form 4Held by the GJN 2021 TRUST
2022-06-22Gary J. NabelChief Innovation OfficerBuy13,229Common Stock$2.50-$33,072.50  0.19     [ Low ]19,857,514$49,643,785.00  291.37   [Very High]Form 4Held by the GJN 2021 TRUST
2022-06-22Gary J. NabelChief Innovation OfficerBuy31,023Common Stock$2.50-$77,557.50  0.46     [ Average ]19,808,537$49,521,342.50  290.65   [Very High]Form 4Held by the EGN 2021 TRUST
2022-06-22Gary J. NabelChief Innovation OfficerBuy15,200Common Stock$2.50-$38,000.00  0.22     [ Low ]19,823,737$49,559,342.50  290.87   [Very High]Form 4Held by the EGN 2021 TRUST
2022-06-22Gary J. NabelChief Innovation OfficerBuy33,777Common Stock$2.50-$84,442.50  0.50     [ Average ]19,857,514$49,643,785.00  291.37   [Very High]Form 4Held by the EGN 2021 TRUST
2022-06-22Gary J. NabelChief Innovation OfficerBuy80,000Common Stock$2.47-$197,600.00  1.17     [ High ]80,000$197,600.00  1.17     [Very Low]Form 4Held by Nabel Family Investments LLC