SPRUCE BIOSCIENCES, INC.

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SPRUCE BIOSCIENCES, INC.

$SPRB

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Trade Date Insider Title Buy or Sell Quantity Security Type Price Proceeds Transaction Conviction Position Quantity Position Value Positon Conviction SEC Link Nature of Ownership
2020-10-14Holdings A/s Novo-Buy4,739,336COMMON STOCK$0.00$0.00  -4,739,336$0.00  2,128.32 [Very High]Form 4-
2020-10-14Holdings A/s Novo-Buy250,000COMMON STOCK$15.00-$3,750,000.00  112.27   [ Very High ]4,989,336$74,840,040.00  2,240.59 [Very High]Form 4-
2020-10-14Rivervest Venture Fund Iii, L.p.-Buy1,070,172Common Stock$0.00$0.00  -1,070,172$0.00  480.59   [Very High]Form 4See footnotes
2020-10-14Rivervest Venture Fund Iii, L.p.-Buy828,109Common Stock$0.00$0.00  -1,898,281$0.00  852.47   [Very High]Form 4See footnotes
2020-10-14Rivervest Venture Fund Iii, L.p.-Buy250,000Common Stock$15.00-$3,750,000.00  112.27   [ Very High ]2,148,281$32,224,215.00  964.74   [Very High]Form 4See footnote
2020-10-14Jonas Hansson-Buy1,783,621Common Stock$0.00$0.00  -1,783,621$0.00  800.98   [Very High]Form 4See Footnotes
2020-10-14Jonas Hansson-Buy250,000Common Stock$15.00-$3,750,000.00  112.27   [ Very High ]2,033,621$30,504,315.00  913.25   [Very High]Form 4See Footnotes
2020-10-14Viii, L.p. Healthcap-Buy1,783,621Common Stock$0.00$0.00  -1,783,621$0.00  800.98   [Very High]Form 4-
2020-10-14Viii, L.p. Healthcap-Buy250,000Common Stock$15.00-$3,750,000.00  112.27   [ Very High ]2,033,621$30,504,315.00  913.25   [Very High]Form 4-
2020-10-14Moghrabi Dina Chaya-Buy1,911,022Common Stock$0.00$0.00  -1,911,022$0.00  858.19   [Very High]Form 4See Footnotes
2020-10-14Moghrabi Dina Chaya-Buy250,000Common Stock$15.00-$3,750,000.00  112.27   [ Very High ]2,161,022$32,415,330.00  970.46   [Very High]Form 4See Footnotes
2020-10-14Omega Fund Vi, L.p.-Buy1,911,022Common Stock$0.00$0.00  -1,911,022$0.00  858.19   [Very High]Form 4-
2020-10-14Omega Fund Vi, L.p.-Buy250,000Common Stock$15.00-$3,750,000.00  112.27   [ Very High ]2,161,022$32,415,330.00  970.46   [Very High]Form 4-
2020-10-14Niall O'donnell-Buy445,905Common Stock$0.00$0.00  -445,905$0.00  200.24   [Very High]Form 4By RiverVest Venture Fund IV, L.P.
2020-10-14Niall O'donnell-Buy250,000Common Stock$15.00-$3,750,000.00  112.27   [ Very High ]695,905$10,438,575.00  312.51   [Very High]Form 4By RiverVest Venture Fund IV, L.P.
2020-10-14Bali Muralidhar-Buy1,592,518Common Stock$0.00$0.00  -1,592,518$0.00  715.16   [Very High]Form 4See Footnotes
2020-10-14Bali Muralidhar-Buy200,000Common Stock$15.00-$3,000,000.00  89.81    [ Very High ]1,792,518$26,887,770.00  804.97   [Very High]Form 4See Footnotes