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Trade Date Insider Title Buy or Sell Quantity Security Type Price Proceeds Transaction Conviction Position Quantity Position Value Positon Conviction SEC Link Nature of Ownership
2020-06-01Shire Human Genetic Therapies, Inc.-Sell107,072Common Stock$19.85$2,125,379.20  -6,971,873$138,391,679.05  -Form 4-
2020-06-01Shire Human Genetic Therapies, Inc.-Sell1,400Common Stock$20.53$28,742.00  -6,970,473$143,103,810.69  -Form 4-
2020-06-02Shire Human Genetic Therapies, Inc.-Sell100,389Common Stock$19.75$1,982,682.75  -6,870,084$135,684,159.00  -Form 4-
2020-06-02Shire Human Genetic Therapies, Inc.-Sell5,006Common Stock$20.02$100,220.12  -6,865,078$137,438,861.56  -Form 4-
2020-06-03Shire Human Genetic Therapies, Inc.-Sell40,086Common Stock$19.75$791,698.50  -6,824,992$134,793,592.00  -Form 4-
2020-06-26Group Llc/ma Baupost-Buy500,000Common Stock$22.00-$11,000,000.00  -18,044,239$396,973,258.00  -Form 4See footnote 1 and 2.
2020-06-30Shire Human Genetic Therapies, Inc.-Sell6,824,992Common Stock$20.68$141,140,834.56  -0$0.00  -Form 4-
2020-08-25Jean Francois Formela-Sell34,410Common Stock$15.00$516,150.00  4.63     [ Very High ]3,887,600$58,314,000.00  523.62   [Very High]Form 4See Footnote
2020-08-26Jean Francois Formela-Sell44,381Common Stock$14.80$656,838.80  5.98     [ Very High ]3,843,219$56,879,641.20  517.65   [Very High]Form 4See Footnote
2020-08-27Jean Francois Formela-Sell10,097Common Stock$14.38$145,194.86  1.36     [ High ]3,833,122$55,120,294.36  516.29   [Very High]Form 4See Footnote
2020-11-16Renaud Ronald C JrChief Executive Officer, Pres.Buy53,004Common Stock$7.39-$391,699.56  7.13     [ Very High ]488,563$3,610,480.57  65.74    [High]Form 4-
2020-11-16Renaud Ronald C JrChief Executive Officer, Pres.Buy3Common Stock$8.34-$25.02  -488,566$4,074,640.44  65.74    [High]Form 4-
2020-12-21Jean Francois Formela-Sell56,536Common Stock$25.50$1,441,668.00  7.61     [ Very High ]126,505$3,225,877.50  17.02    [High]Form 4See Footnote
2020-12-22Jean Francois Formela-Sell79,865Common Stock$25.04$1,999,819.60  10.75    [ Very High ]46,640$1,167,865.60  6.28     [Average]Form 4See Footnote
2020-12-22Jean Francois Formela-Sell2,700Common Stock$25.88$69,876.00  0.36     [ Average ]43,940$1,137,167.20  5.91     [Average]Form 4See Footnote
2021-01-14Renaud Ronald C JrChief Executive Officer, Pres.Buy5,638Common Stock$7.39-$41,664.82  0.76     [ Average ]494,204$3,652,167.56  66.49    [High]Form 4-
2021-01-14Renaud Ronald C JrChief Executive Officer, Pres.Buy1Common Stock$8.34-$8.34  -494,205$4,121,669.70  66.50    [High]Form 4-
2021-09-14Jean Francois Formela-Sell2,055,063Common Stock$38.00$78,092,394.00  271.88   [ Very High ]0$0.00  -Form 4See Footnote
2021-09-14Sanofi-Buy51,467,612Common Stock, par value $0.001 per share$38.00-$1,955,769,256.00  6,809.06 [ Very High ]55,152,046$2,095,777,748.00  7,296.50 [Very High]Form 4-
2021-09-14Sanofi-Buy20,515,985Common Stock, par value $0.001 per share$38.00-$779,607,430.00  2,714.22 [ Very High ]75,668,031$2,875,385,178.00  10,010.72[Very High]Form 4-
2021-09-14Renaud Ronald C JrChief Executive OfficerSell503,231Common Stock$38.00$19,122,778.00  66.58    [ Very High ]0$0.00  -Form 4-
2021-09-14Renaud Ronald C JrChief Executive OfficerSell409,913Common Stock$38.00$15,576,694.00  54.23    [ Very High ]0$0.00  -Form 4By Ronald Renaud 2014 Irrevocable Family Trust
2021-09-14Renaud Ronald C JrChief Executive OfficerSell40,909Common Stock$38.00$1,554,542.00  5.41     [ Very High ]0$0.00  -Form 4By Ronald C. Renaud, Jr. Trust - 2007
2021-09-14Owen Hughes-Sell29,860Common Stock$38.00$1,134,680.00  3.95     [ Very High ]0$0.00  -Form 4-
2021-09-14Paul D. BurgessChief Operating Officer, CLOSell71,833Common Stock$38.00$2,729,654.00  9.50     [ Very High ]0$0.00  -Form 4-