Vir Biotechnology, Inc.

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Vir Biotechnology, Inc.

$VIR

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Trade Date Insider Title Buy or Sell Quantity Security Type Price Proceeds Transaction Conviction Position Quantity Position Value Positon Conviction SEC Link Nature of Ownership
2020-08-03Jay ParrishChief Business OfficerBuy1,851Common Stock$1.57-$2,906.07  0.15     [ Low ]233,332$366,331.24  18.66    [High]Form 4-
2020-08-03Jay ParrishChief Business OfficerBuy9,259Common Stock$1.49-$13,795.91  0.74     [ Average ]231,481$344,906.69  18.51    [High]Form 4-
2020-07-28Herbert VirginEVP, Research & CSOSell7,900Common Stock$47.99$379,121.00  0.63     [ Average ]0$0.00  -Form 4-
2020-07-28Herbert VirginEVP, Research & CSOSell7,900Common Stock$47.99$379,121.00  0.63     [ Average ]0$0.00  -Form 4-
2020-07-28Herbert VirginEVP, Research & CSOBuy7,900Common Stock$1.53-$12,087.00  0.63     [ Average ]7,900$12,087.00  0.63     [Very Low]Form 4-
2020-07-14Herbert VirginEVP, Research & CSOSell7,900Common Stock$48.85$385,915.00  0.63     [ Average ]0$0.00  -Form 4-
2020-07-14Herbert VirginEVP, Research & CSOBuy7,900Common Stock$1.53-$12,087.00  0.63     [ Average ]7,900$12,087.00  0.63     [Very Low]Form 4-
2020-07-15Phillip PangChief Medical OfficerSell7,500Common Stock$49.52$371,400.00  0.60     [ Average ]15,777$781,277.04  1.26     [Very Low]Form 4-
2020-07-15Phillip PangChief Medical OfficerSell5,000Common Stock$49.54$247,700.00  0.40     [ Average ]23,277$1,153,142.58  1.86     [Low]Form 4-
2020-07-15Phillip PangChief Medical OfficerBuy10,186Common Stock$1.57-$15,992.02  0.81     [ High ]25,963$40,761.91  2.08     [Low]Form 4-
2020-07-15Phillip PangChief Medical OfficerBuy2,314Common Stock$5.17-$11,963.38  0.19     [ Low ]28,277$146,192.09  2.26     [Low]Form 4-
2020-04-14George A ScangosPresident and CEOSell236,806Common Stock$29.56$6,999,985.36  18.94    [ Very High ]1,907,329$56,380,645.24  152.53   [Very High]Form 4See footnote
2020-04-14George A ScangosPresident and CEOBuy236,806Common Stock$29.56-$6,999,985.36  18.94    [ Very High ]4,713,559$139,332,804.04  376.95   [Very High]Form 4-
2020-04-17Phillip PangChief Medical OfficerBuy8,000Common Stock$0.85-$6,800.00  0.64     [ Average ]15,777$13,410.45  1.26     [Very Low]Form 4-
2020-05-01Robert J More-Sell15,758Common Stock$27.90$439,648.20  1.26     [ High ]74,234$2,071,128.60  5.94     [Average]Form 4-
2020-05-01Robert J More-Sell2,700Common Stock$28.60$77,220.00  0.22     [ Low ]71,534$2,045,872.40  5.72     [Average]Form 4-
2020-05-14Jay ParrishChief Business OfficerBuy75,000Common Stock$1.49-$111,750.00  6.00     [ Very High ]297,222$442,860.78  23.77    [High]Form 4-
2020-05-14Jay ParrishChief Business OfficerSell75,000Common Stock$30.05$2,253,750.00  6.00     [ Very High ]222,222$6,677,771.10  17.77    [High]Form 4-
2020-05-14Herbert VirginEVP, Research & CSOBuy3,805Common Stock$1.53-$5,821.65  0.30     [ Average ]3,805$5,821.65  0.30     [Very Low]Form 4-
2020-05-14Herbert VirginEVP, Research & CSOSell3,805Common Stock$30.07$114,416.35  0.30     [ Average ]0$0.00  -Form 4-
2020-05-18Herbert VirginEVP, Research & CSOBuy1,755Common Stock$1.53-$2,685.15  0.14     [ Low ]1,755$2,685.15  0.14     [Very Low]Form 4-
2020-05-18Herbert VirginEVP, Research & CSOSell1,755Common Stock$38.00$66,690.00  0.14     [ Low ]0$0.00  -Form 4-
2020-05-26Herbert VirginEVP, Research & CSOBuy3,805Common Stock$1.53-$5,821.65  0.30     [ Average ]3,805$5,821.65  0.30     [Very Low]Form 4-
2020-05-26Herbert VirginEVP, Research & CSOSell3,805Common Stock$34.08$129,674.40  0.30     [ Average ]0$0.00  -Form 4-
2020-06-01Howard HornCFOSell3,286Common Stock$34.53$113,465.58  -274,491$9,478,174.23  -Form 4-
2020-06-01Howard HornCFOSell6,714Common Stock$35.38$237,541.32  -267,777$9,473,950.26  -Form 4-
2020-06-01Jay ParrishChief Business OfficerBuy75,000Common Stock$1.49-$111,750.00  -297,222$442,860.78  -Form 4-
2020-06-01Jay ParrishChief Business OfficerSell75,000Common Stock$35.22$2,641,500.00  -222,222$7,826,658.84  -Form 4-
2020-06-03Phillip PangChief Medical OfficerBuy12,500Common Stock$5.17-$64,625.00  -28,277$146,192.09  -Form 4-
2020-06-03Phillip PangChief Medical OfficerSell5,000Common Stock$35.09$175,450.00  -23,277$816,789.93  -Form 4-
2020-06-03Phillip PangChief Medical OfficerSell7,500Common Stock$35.06$262,950.00  -15,777$553,141.62  -Form 4-
2020-06-09Herbert VirginEVP, Research & CSOBuy3,805Common Stock$1.53-$5,821.65  -3,805$5,821.65  -Form 4-
2020-06-09Herbert VirginEVP, Research & CSOSell3,805Common Stock$36.28$138,045.40  -0$0.00  -Form 4-
2020-07-13Howard HornCFOSell30,000Common Stock$50.06$1,501,800.00  2.40     [ Very High ]177,777$8,899,516.62  14.22    [Average]Form 4-
2020-06-17Phillip PangChief Medical OfficerBuy12,500Common Stock$5.17-$64,625.00  -28,277$146,192.09  -Form 4-
2020-06-17Phillip PangChief Medical OfficerSell5,000Common Stock$37.27$186,350.00  -23,277$867,533.79  -Form 4-
2020-06-17Phillip PangChief Medical OfficerSell7,500Common Stock$37.26$279,450.00  -15,777$587,851.02  -Form 4-
2020-06-19Herbert VirginEVP, Research & CSOBuy3,510Common Stock$1.53-$5,370.30  -3,510$5,370.30  -Form 4-
2020-06-19Herbert VirginEVP, Research & CSOSell1,755Common Stock$38.00$66,690.00  -1,755$66,690.00  -Form 4-
2020-06-19Herbert VirginEVP, Research & CSOSell1,755Common Stock$38.00$66,690.00  -0$0.00  -Form 4-
2020-06-19Howard HornCFOSell10,000Common Stock$40.00$400,000.00  -257,777$10,311,080.00  -Form 4-
2020-06-23Herbert VirginEVP, Research & CSOBuy5,560Common Stock$1.53-$8,506.80  -5,560$8,506.80  -Form 4-
2020-06-23Herbert VirginEVP, Research & CSOSell5,560Common Stock$38.99$216,784.40  -0$0.00  -Form 4-
2020-06-24Herbert VirginEVP, Research & CSOBuy9,360Common Stock$1.53-$14,320.80  -9,360$14,320.80  -Form 4-
2020-06-24Herbert VirginEVP, Research & CSOSell9,360Common Stock$48.00$449,280.00  -0$0.00  -Form 4-
2020-06-25Howard HornCFOSell30,000Common Stock$50.00$1,500,000.00  -227,777$11,388,850.00  -Form 4-
2020-08-03Jay ParrishChief Business OfficerSell11,110Common Stock$47.65$529,391.50  0.89     [ High ]222,222$10,588,878.30  17.77    [High]Form 4-
2020-08-05Phillip PangChief Medical OfficerBuy12,500Common Stock$1.57-$19,625.00  0.99     [ High ]28,277$44,394.89  2.24     [Low]Form 4-
2020-08-05Phillip PangChief Medical OfficerSell5,000Common Stock$50.91$254,550.00  0.40     [ Average ]23,277$1,185,032.07  1.85     [Low]Form 4-
2020-08-05Phillip PangChief Medical OfficerSell7,500Common Stock$50.89$381,675.00  0.59     [ Average ]15,777$802,891.53  1.25     [Very Low]Form 4-
2020-08-05Phillip PangChief Medical OfficerSell5,000Common Stock$50.91$254,550.00  0.40     [ Average ]23,277$1,185,032.07  1.85     [Low]Form 4-
2020-08-05Phillip PangChief Medical OfficerSell7,500Common Stock$50.89$381,675.00  0.59     [ Average ]15,777$802,891.53  1.25     [Very Low]Form 4-
2020-08-11Herbert VirginEVP, Research & CSOBuy7,900Common Stock$1.53-$12,087.00  0.63     [ Average ]7,900$12,087.00  0.63     [Very Low]Form 4-
2020-08-11Herbert VirginEVP, Research & CSOSell7,900Common Stock$51.08$403,532.00  0.63     [ Average ]0$0.00  -Form 4-
2020-08-19Phillip PangChief Medical OfficerBuy10,185Common Stock$1.57-$15,990.45  0.80     [ High ]25,962$40,760.34  2.04     [Low]Form 4-
2020-08-19Phillip PangChief Medical OfficerBuy2,315Common Stock$5.17-$11,968.55  0.18     [ Low ]28,277$146,192.09  2.23     [Low]Form 4-
2020-08-19Phillip PangChief Medical OfficerBuy14,000Common Stock$0.85-$11,900.00  1.10     [ High ]42,277$35,935.45  3.33     [Low]Form 4-
2020-08-19Phillip PangChief Medical OfficerSell5,000Common Stock$50.96$254,800.00  0.39     [ Average ]37,277$1,899,635.92  2.93     [Low]Form 4-
2020-08-19Phillip PangChief Medical OfficerSell7,500Common Stock$50.94$382,050.00  0.59     [ Average ]29,777$1,516,840.38  2.34     [Low]Form 4-
2020-09-01Jay ParrishChief Business OfficerBuy6,943Common Stock$1.57-$10,900.51  0.55     [ Average ]229,165$359,789.05  18.04    [High]Form 4-
2020-09-01Jay ParrishChief Business OfficerSell6,943Common Stock$39.15$271,818.45  0.55     [ Average ]222,222$8,699,991.30  17.49    [High]Form 4-
2020-09-02Phillip PangChief Medical OfficerBuy12,500Common Stock$1.57-$19,625.00  0.98     [ High ]42,277$66,374.89  3.33     [Low]Form 4-
2020-09-02Phillip PangChief Medical OfficerSell7,500Common Stock$32.88$246,600.00  0.59     [ Average ]34,777$1,143,467.76  2.74     [Low]Form 4-
2020-09-02Phillip PangChief Medical OfficerSell5,000Common Stock$32.91$164,550.00  0.39     [ Average ]29,777$979,961.07  2.34     [Low]Form 4-
2020-08-25Herbert VirginEVP, Research & CSOBuy25,560Common Stock$1.53-$39,106.80  2.01     [ High ]25,560$39,106.80  2.01     [Low]Form 4-
2020-08-25Herbert VirginEVP, Research & CSOSell5,560Common Stock$42.92$238,635.20  0.44     [ Average ]20,000$858,400.00  1.57     [Low]Form 4-
2020-09-08Herbert VirginEVP, Research & CSOBuy3,805Common Stock$1.53-$5,821.65  0.30     [ Average ]23,805$36,421.65  1.87     [Low]Form 4-
2020-09-08Herbert VirginEVP, Research & CSOSell1,465Common Stock$30.00$43,950.00  0.12     [ Low ]22,340$670,200.00  1.76     [Low]Form 4-
2020-09-08Herbert VirginEVP, Research & CSOSell2,340Common Stock$29.98$70,153.20  0.18     [ Low ]20,000$599,600.00  1.57     [Low]Form 4-
2020-09-16Phillip PangChief Medical OfficerBuy9,720Common Stock$1.57-$15,260.40  0.77     [ Average ]39,497$62,010.29  3.11     [Low]Form 4-
2020-09-16Phillip PangChief Medical OfficerBuy465Common Stock$1.53-$711.45  0.04     [ Very Low ]39,962$61,141.86  3.15     [Low]Form 4-
2020-09-16Phillip PangChief Medical OfficerBuy2,315Common Stock$5.17-$11,968.55  0.18     [ Low ]42,277$218,572.09  3.33     [Low]Form 4-
2020-09-16Phillip PangChief Medical OfficerSell7,500Common Stock$31.88$239,100.00  0.59     [ Average ]34,777$1,108,690.76  2.74     [Low]Form 4-
2020-09-16Phillip PangChief Medical OfficerSell5,000Common Stock$31.92$159,600.00  0.39     [ Average ]29,777$950,481.84  2.34     [Low]Form 4-
2020-09-22Herbert VirginEVP, Research & CSOBuy3,805Common Stock$1.53-$5,821.65  0.30     [ Average ]23,805$36,421.65  1.87     [Low]Form 4-
2020-09-22Herbert VirginEVP, Research & CSOSell3,805Common Stock$31.71$120,656.55  0.30     [ Average ]20,000$634,200.00  1.57     [Low]Form 4-
2020-09-24Herbert VirginEVP, Research & CSOBuy3,700Common Stock$1.53-$5,661.00  0.29     [ Low ]23,700$36,261.00  1.87     [Low]Form 4-
2020-09-29Herbert VirginEVP, Research & CSOBuy3,510Common Stock$1.53-$5,370.30  0.28     [ Low ]27,210$41,631.30  2.14     [Low]Form 4-
2020-09-29Herbert VirginEVP, Research & CSOSell3,510Common Stock$38.00$133,380.00  0.28     [ Low ]23,700$900,600.00  1.87     [Low]Form 4-
2020-10-01Jay ParrishChief Business OfficerBuy4,630Common Stock$1.49-$6,898.70  0.36     [ Average ]226,852$338,009.48  17.85    [High]Form 4-
2020-10-01Jay ParrishChief Business OfficerBuy2,315Common Stock$1.57-$3,634.55  0.18     [ Low ]229,167$359,792.19  18.04    [High]Form 4-
2020-10-01Jay ParrishChief Business OfficerSell6,945Common Stock$34.75$241,338.75  0.55     [ Average ]222,222$7,722,214.50  17.49    [High]Form 4-
2020-10-07Phillip PangChief Medical OfficerBuy10,185Common Stock$1.53-$15,583.05  0.80     [ High ]39,962$61,141.86  3.15     [Low]Form 4-
2020-10-07Phillip PangChief Medical OfficerBuy2,315Common Stock$1.57-$3,634.55  0.18     [ Low ]42,277$66,374.89  3.33     [Low]Form 4-
2020-10-07Phillip PangChief Medical OfficerSell7,500Common Stock$41.76$313,200.00  0.59     [ Average ]34,777$1,452,287.52  2.74     [Low]Form 4-
2020-10-07Phillip PangChief Medical OfficerSell5,000Common Stock$41.73$208,650.00  0.39     [ Average ]29,777$1,242,594.21  2.34     [Low]Form 4-
2020-10-13Herbert VirginEVP, Research & CSOBuy5,560Common Stock$1.53-$8,506.80  0.44     [ Average ]29,260$44,767.80  2.30     [Low]Form 4-
2020-10-13Herbert VirginEVP, Research & CSOSell5,560Common Stock$43.03$239,246.80  0.44     [ Average ]23,700$1,019,811.00  1.87     [Low]Form 4-
2020-10-21Phillip PangChief Medical OfficerBuy7,870Common Stock$1.53-$12,041.10  0.62     [ Average ]37,647$57,599.91  2.96     [Low]Form 4-
2020-10-21Phillip PangChief Medical OfficerBuy2,315Common Stock$1.57-$3,634.55  0.18     [ Low ]39,962$62,740.34  3.15     [Low]Form 4-
2020-10-21Phillip PangChief Medical OfficerBuy2,315Common Stock$5.17-$11,968.55  0.18     [ Low ]42,277$218,572.09  3.33     [Low]Form 4-
2020-10-21Phillip PangChief Medical OfficerSell7,500Common Stock$35.42$265,650.00  0.59     [ Average ]34,777$1,231,801.34  2.74     [Low]Form 4-
2020-10-21Phillip PangChief Medical OfficerSell5,000Common Stock$35.59$177,950.00  0.39     [ Average ]29,777$1,059,763.43  2.34     [Low]Form 4-
2020-10-27Herbert VirginEVP, Research & CSOBuy3,805Common Stock$1.53-$5,821.65  0.30     [ Average ]27,505$42,082.65  2.16     [Low]Form 4-
2020-10-27Herbert VirginEVP, Research & CSOSell3,805Common Stock$35.04$133,327.20  0.30     [ Average ]23,700$830,448.00  1.87     [Low]Form 4-
2020-11-02Jay ParrishChief Business OfficerBuy4,629Common Stock$1.49-$6,897.21  0.36     [ Average ]226,851$338,007.99  17.85    [High]Form 4-
2020-11-02Jay ParrishChief Business OfficerBuy2,315Common Stock$1.57-$3,634.55  0.18     [ Low ]229,166$359,790.62  18.04    [High]Form 4-
2020-11-02Jay ParrishChief Business OfficerSell6,944Common Stock$31.27$217,138.88  0.55     [ Average ]222,222$6,948,881.94  17.49    [High]Form 4-
2020-11-04Phillip PangChief Medical OfficerBuy5,000Common Stock$1.53-$7,650.00  0.39     [ Average ]34,777$53,208.81  2.74     [Low]Form 4-
2020-10-21Phillip PangChief Medical OfficerSell5,000Common Stock$31.44$157,200.00  0.39     [ Average ]29,777$936,188.88  2.34     [Low]Form 4-
2020-11-10Herbert VirginEVP, Research & CSOBuy2,340Common Stock$1.53-$3,580.20  0.18     [ Low ]26,040$39,841.20  2.04     [Low]Form 4-
2020-11-10Herbert VirginEVP, Research & CSOSell2,340Common Stock$26.26$61,448.40  0.18     [ Low ]23,700$622,362.00  1.86     [Low]Form 4-
2020-11-12Phillip PangChief Medical OfficerBuy20,000Common Stock$0.85-$17,000.00  1.57     [ High ]49,777$42,310.45  3.91     [Low]Form 4-
2020-11-24Herbert VirginEVP, Research & CSOBuy2,340Common Stock$1.53-$3,580.20  0.18     [ Low ]26,040$39,841.20  2.04     [Low]Form 4-
2020-11-24Herbert VirginEVP, Research & CSOSell2,340Common Stock$27.29$63,858.60  0.18     [ Low ]23,700$646,773.00  1.86     [Low]Form 4-
2020-11-27Herbert VirginEVP, Research & CSOBuy2,930Common Stock$1.53-$4,482.90  0.23     [ Low ]26,630$40,743.90  2.09     [Low]Form 4-
2020-11-27Herbert VirginEVP, Research & CSOSell2,930Common Stock$30.00$87,900.00  0.23     [ Low ]23,700$711,000.00  1.86     [Low]Form 4-
2020-11-27Phillip PangChief Medical OfficerBuy7,500Common Stock$0.85-$6,375.00  0.59     [ Average ]57,277$48,685.45  4.50     [Low]Form 4-
2020-12-01Jay ParrishChief Business OfficerBuy4,630Common Stock$1.49-$6,898.70  0.36     [ Average ]226,852$338,009.48  17.81    [High]Form 4-
2020-12-01Jay ParrishChief Business OfficerBuy2,315Common Stock$1.57-$3,634.55  0.18     [ Low ]229,167$359,792.19  17.99    [High]Form 4-
2020-12-01Jay ParrishChief Business OfficerSell6,945Common Stock$31.53$218,975.85  0.55     [ Average ]222,222$7,006,659.66  17.44    [High]Form 4-
2020-12-08Herbert VirginEVP, Research & CSOBuy3,805Common Stock$1.53-$5,821.65  0.30     [ Average ]27,505$42,082.65  2.16     [Low]Form 4-
2020-12-08Herbert VirginEVP, Research & CSOSell3,805Common Stock$31.27$118,982.35  0.30     [ Average ]23,700$741,099.00  1.86     [Low]Form 4-
2020-12-22Herbert VirginEVP, Research & CSOBuy3,805Common Stock$1.53-$5,821.65  0.30     [ Low ]27,505$42,082.65  2.16     [Low]Form 4-
2020-12-22Herbert VirginEVP, Research & CSOSell3,805Common Stock$31.19$118,677.95  0.30     [ Low ]23,700$739,203.00  1.86     [Low]Form 4-
2020-12-24Herbert VirginEVP, Research & CSOBuy9,500Common Stock$1.53-$14,535.00  0.75     [ Average ]33,200$50,796.00  2.61     [Low]Form 4-
2021-01-04Jay ParrishChief Business OfficerBuy6,945Common Stock$1.49-$10,348.05  0.55     [ Average ]229,167$341,458.83  17.99    [High]Form 4-
2021-01-04Jay ParrishChief Business OfficerSell6,945Common Stock$26.32$182,792.40  0.55     [ Average ]222,222$5,848,883.04  17.44    [High]Form 4-
2021-01-12Herbert VirginEVP, Research & CSOBuy3,805Common Stock$1.53-$5,821.65  0.30     [ Average ]37,005$56,617.65  2.90     [Low]Form 4-
2021-01-12Herbert VirginEVP, Research & CSOSell3,805Common Stock$29.36$111,714.80  0.30     [ Average ]33,200$974,752.00  2.61     [Low]Form 4-
2021-01-15Herbert VirginEVP, Research & CSOBuy10,530Common Stock$1.53-$16,110.90  0.83     [ High ]43,730$66,906.90  3.43     [Low]Form 4-
2021-01-15Herbert VirginEVP, Research & CSOSell10,530Common Stock$38.00$400,140.00  0.83     [ High ]33,200$1,261,600.00  2.61     [Low]Form 4-
2021-01-26Herbert VirginEVP, Research & CSOBuy31,300Common Stock$1.53-$47,889.00  2.46     [ High ]64,500$98,685.00  5.06     [Average]Form 4-
2021-01-26Herbert VirginEVP, Research & CSOSell31,300Common Stock$48.17$1,507,721.00  2.46     [ High ]33,200$1,599,244.00  2.61     [Low]Form 4-
2021-02-01Jay ParrishChief Business OfficerBuy2,314Common Stock$1.49-$3,447.86  0.18     [ Low ]224,536$334,558.64  17.63    [High]Form 4-
2021-02-01Jay ParrishChief Business OfficerBuy4,630Common Stock$1.57-$7,269.10  0.36     [ Average ]229,166$359,790.62  17.99    [High]Form 4-
2021-02-01Jay ParrishChief Business OfficerSell6,944Common Stock$69.91$485,455.04  0.55     [ Average ]222,222$15,535,540.02  17.44    [High]Form 4-
2021-02-09Herbert VirginEVP, Research & CSOBuy7,900Common Stock$1.53-$12,087.00  0.62     [ Average ]41,100$62,883.00  3.23     [Low]Form 4-
2021-02-09Herbert VirginEVP, Research & CSOSell7,900Common Stock$71.16$562,164.00  0.62     [ Average ]33,200$2,362,512.00  2.61     [Low]Form 4-
2021-02-12Phillip PangChief Medical OfficerBuy10,000Common Stock$0.85-$8,500.00  0.78     [ Average ]67,277$57,185.45  5.28     [Average]Form 4-
2021-02-16George A ScangosPresident and CEOBuy111,000Common Stock$0.00$0.00  -4,609,559$0.00  361.85   [Very High]Form 4-
2021-02-16Steven J. RiceChief Administrative OfficerBuy20,000Common Stock$0.00$0.00  -20,000$0.00  1.57     [Low]Form 4-
2021-02-16Herbert VirginEVP, Research & CSOBuy30,000Common Stock$0.00$0.00  -63,200$0.00  4.96     [Average]Form 4-
2021-02-16Howard HornCFOBuy25,000Common Stock$0.00$0.00  -202,777$0.00  15.92    [High]Form 4-
2021-02-16Phillip PangChief Medical OfficerBuy10,000Common Stock$0.85-$8,500.00  0.78     [ Average ]77,277$65,685.45  6.07     [Average]Form 4-
2021-02-16Phillip PangChief Medical OfficerBuy32,000Common Stock$0.00$0.00  -109,277$0.00  8.58     [Average]Form 4-
2021-02-23Herbert VirginEVP, Research & CSOBuy18,900Common Stock$1.53-$28,917.00  1.48     [ High ]82,100$125,613.00  6.44     [Average]Form 4-
2021-02-23Herbert VirginEVP, Research & CSOSell7,900Common Stock$63.74$503,546.00  0.62     [ Average ]74,200$4,729,508.00  5.82     [Average]Form 4-
2021-03-01Jay ParrishChief Business OfficerBuy4,630Common Stock$1.49-$6,898.70  0.36     [ Average ]13,890$20,696.10  1.09     [Very Low]Form 4-
2021-03-01Jay ParrishChief Business OfficerBuy2,314Common Stock$1.57-$3,632.98  0.18     [ Low ]16,204$25,440.28  1.27     [Low]Form 4-
2021-03-01Jay ParrishChief Business OfficerSell6,944Common Stock$63.44$440,527.36  0.54     [ Average ]9,260$587,454.40  0.72     [Very Low]Form 4-
2021-03-09Herbert VirginEVP, Research & CSOBuy5,560Common Stock$1.53-$8,506.80  0.43     [ Average ]79,760$122,032.80  6.24     [Average]Form 4-
2021-03-09Herbert VirginEVP, Research & CSOSell5,560Common Stock$44.80$249,088.00  0.43     [ Average ]74,200$3,324,160.00  5.80     [Average]Form 4-
2021-03-10Herbert VirginEVP, Research & CSOBuy2,340Common Stock$1.53-$3,580.20  0.18     [ Low ]76,540$117,106.20  5.99     [Average]Form 4-
2021-03-10Herbert VirginEVP, Research & CSOSell2,340Common Stock$48.00$112,320.00  0.18     [ Low ]74,200$3,561,600.00  5.80     [Average]Form 4-
2021-03-23Herbert VirginEVP, Research & CSOBuy7,900Common Stock$1.53-$12,087.00  0.62     [ Average ]82,100$125,613.00  6.42     [Average]Form 4-
2021-03-23Herbert VirginEVP, Research & CSOSell7,900Common Stock$53.60$423,440.00  0.62     [ Average ]74,200$3,977,120.00  5.80     [Average]Form 4-
2021-03-30Arch Venture Partners Ix, Llc-Sell217,781Common Stock$0.00$0.00  -12,268,328$0.00  959.69   [Very High]Form 4See footnote
2021-03-30Arch Venture Partners Ix, Llc-Sell282,219Common Stock$0.00$0.00  -15,898,335$0.00  1,243.64 [Very High]Form 4See footnote
2021-03-30Arch Venture Partners Ix, Llc-Buy3,160Common Stock$0.00$0.00  -3,160$0.00  0.25     [Very Low]Form 4-
2021-03-30Arch Venture Partners Ix, Llc-Buy1,014Common Stock$0.00$0.00  -1,014$0.00  0.08     [Very Low]Form 4-
2021-04-01Arch Venture Partners Ix, Llc-Sell217,781Common Stock$0.00$0.00  -12,050,547$0.00  942.65   [Very High]Form 4See footnote
2021-04-01Arch Venture Partners Ix, Llc-Sell282,219Common Stock$0.00$0.00  -15,616,116$0.00  1,221.56 [Very High]Form 4See footnote
2021-04-01Arch Venture Partners Ix, Llc-Buy3,160Common Stock$0.00$0.00  -6,320$0.00  0.49     [Very Low]Form 4-
2021-04-01Arch Venture Partners Ix, Llc-Buy1,016Common Stock$0.00$0.00  -2,030$0.00  0.16     [Very Low]Form 4-
2021-03-30Robert Nelsen-Sell217,781Common Stock$0.00$0.00  -12,268,328$0.00  959.69   [Very High]Form 4See footnote
2021-03-30Robert Nelsen-Sell282,219Common Stock$0.00$0.00  -15,898,335$0.00  1,243.64 [Very High]Form 4See footnote
2021-03-30Robert Nelsen-Buy5,989Common Stock$0.00$0.00  -5,989$0.00  0.47     [Very Low]Form 4-
2021-04-01Robert Nelsen-Sell217,781Common Stock$0.00$0.00  -12,050,547$0.00  942.65   [Very High]Form 4See footnote
2021-04-01Robert Nelsen-Sell282,219Common Stock$0.00$0.00  -15,616,116$0.00  1,221.56 [Very High]Form 4See footnote
2021-04-01Robert Nelsen-Buy5,987Common Stock$0.00$0.00  -11,976$0.00  0.94     [Very Low]Form 4-
2021-04-01Jay ParrishChief Business OfficerBuy4,629Common Stock$1.49-$6,897.21  0.36     [ Average ]13,889$20,694.61  1.09     [Very Low]Form 4-
2021-04-01Jay ParrishChief Business OfficerBuy2,315Common Stock$1.57-$3,634.55  0.18     [ Low ]16,204$25,440.28  1.27     [Low]Form 4-
2021-04-01Jay ParrishChief Business OfficerSell6,944Common Stock$51.40$356,921.60  0.54     [ Average ]9,260$475,964.00  0.72     [Very Low]Form 4-
2021-04-13Herbert VirginEVP, Research & CSOSell5,560Common Stock$43.57$242,249.20  0.43     [ Average ]88,200$3,842,874.00  6.89     [Average]Form 4-
2021-04-13Herbert VirginEVP, Research & CSOBuy5,560Common Stock$1.53-$8,506.80  0.43     [ Average ]93,760$143,452.80  7.33     [Average]Form 4-
2021-04-16Herbert VirginEVP, Research & CSOBuy3,500Common Stock$1.53-$5,355.00  0.27     [ Low ]91,700$140,301.00  7.16     [Average]Form 4-
2021-04-19Herbert VirginEVP, Research & CSOBuy2,340Common Stock$1.53-$3,580.20  0.18     [ Low ]94,040$143,881.20  7.35     [Average]Form 4-
2021-04-19Herbert VirginEVP, Research & CSOSell2,340Common Stock$48.00$112,320.00  0.18     [ Low ]91,700$4,401,600.00  7.16     [Average]Form 4-
2021-04-27Herbert VirginEVP, Research & CSOBuy7,900Common Stock$1.53-$12,087.00  0.62     [ Average ]99,600$152,388.00  7.78     [Average]Form 4-
2021-04-27Herbert VirginEVP, Research & CSOSell7,900Common Stock$49.50$391,050.00  0.62     [ Average ]91,700$4,539,150.00  7.16     [Average]Form 4-
2021-05-04Herbert VirginEVP, Research & CSOBuy1,375Common Stock$1.53-$2,103.75  0.11     [ Low ]93,075$142,404.75  7.27     [Average]Form 4-
2021-05-04Herbert VirginEVP, Research & CSOSell1,375Common Stock$46.03$63,291.25  0.11     [ Low ]91,700$4,220,951.00  7.16     [Average]Form 4-
2021-05-18Herbert VirginEVP, Research & CSOBuy1,375Common Stock$1.53-$2,103.75  0.11     [ Low ]93,075$142,404.75  7.16     [Average]Form 4-
2021-05-18Herbert VirginEVP, Research & CSOSell1,375Common Stock$45.03$61,916.25  0.11     [ Low ]91,700$4,129,251.00  7.05     [Average]Form 4-
2021-05-19Vicki L Sato-Sell8,328Common Stock$43.35$361,018.80  0.64     [ Average ]1,660,782$71,994,899.70  127.71   [Very High]Form 4-
2021-05-19Vicki L Sato-Sell5,403Common Stock$44.18$238,704.54  0.42     [ Average ]1,655,379$73,134,644.22  127.30   [Very High]Form 4-
2021-05-19Vicki L Sato-Sell1,443Common Stock$44.96$64,877.28  0.11     [ Low ]1,653,936$74,360,962.56  127.19   [Very High]Form 4-
2021-05-19Saira Ramasastry-Buy10,000Common Stock$12.76-$127,600.00  0.77     [ High ]10,000$127,600.00  0.77     [Very Low]Form 4-
2021-05-19Saira Ramasastry-Sell10,000Common Stock$43.73$437,300.00  0.77     [ High ]0$0.00  -Form 4-
2021-05-20Robert J More-Sell2,575Common Stock$43.57$112,192.75  0.20     [ Low ]98,430$4,288,595.10  7.57     [Average]Form 4-
2021-05-20Robert J More-Sell9,095Common Stock$44.77$407,183.15  0.70     [ Average ]89,335$3,999,527.95  6.87     [Average]Form 4-
2021-05-21Vicki L Sato-Buy3,374Common Stock$0.00$0.00  -1,657,310$0.00  127.45   [Very High]Form 4-
2021-05-21Robert J More-Sell3,374Common Stock$0.00$0.00  -92,709$0.00  7.13     [Average]Form 4-
2021-05-21Robert Nelsen-Buy3,374Common Stock$0.00$0.00  -27,328$0.00  2.10     [Low]Form 4-
2021-05-21Phillip A Sharp-Buy3,374Common Stock$0.00$0.00  -108,742$0.00  8.36     [Average]Form 4-
2021-05-21Robert J Perez-Buy3,374Common Stock$0.00$0.00  -3,374$0.00  0.26     [Very Low]Form 4-
2021-05-21Dipchand Nishar-Buy3,374Common Stock$0.00$0.00  -3,374$0.00  0.26     [Very Low]Form 4-
2021-05-21Saira Ramasastry-Buy3,374Common Stock$0.00$0.00  -3,374$0.00  0.26     [Very Low]Form 4-
2021-05-21Jeffrey S. Hatfield-Buy3,374Common Stock$0.00$0.00  -3,374$0.00  0.26     [Very Low]Form 4-
2021-05-21Charles Elliott Sigal-Buy3,374Common Stock$0.00$0.00  -3,374$0.00  0.26     [Very Low]Form 4-
2021-05-21Janet Napolitano-Buy3,374Common Stock$0.00$0.00  -3,374$0.00  0.26     [Very Low]Form 4-
2021-06-01Herbert VirginEVP, Research & CSOBuy1,375Common Stock$1.53-$2,103.75  0.11     [ Low ]93,075$142,404.75  7.16     [Average]Form 4-
2021-06-01Herbert VirginEVP, Research & CSOSell1,375Common Stock$42.51$58,451.25  0.11     [ Low ]91,700$3,898,167.00  7.05     [Average]Form 4-
2021-06-02Phillip PangChief Medical OfficerBuy10,000Common Stock$0.85-$8,500.00  0.77     [ High ]119,277$101,385.45  9.17     [Average]Form 4-
2021-06-02Phillip PangChief Medical OfficerSell9,700Common Stock$41.47$402,259.00  0.75     [ Average ]109,577$4,544,158.19  8.43     [Average]Form 4-
2021-06-02Phillip PangChief Medical OfficerSell300Common Stock$42.18$12,654.00  0.02     [ Very Low ]109,277$4,609,303.86  8.40     [Average]Form 4-
2021-06-03Robert J More-Sell11,670Common Stock$44.56$520,015.20  0.90     [ High ]81,039$3,611,097.84  6.23     [Average]Form 4-
2021-06-15Herbert VirginEVP, Research & CSOBuy1,375Common Stock$1.53-$2,103.75  0.11     [ Low ]93,075$142,404.75  7.16     [Average]Form 4-
2021-06-15Herbert VirginEVP, Research & CSOSell1,375Common Stock$45.29$62,273.75  0.11     [ Low ]91,700$4,153,093.00  7.05     [Average]Form 4-
2021-06-16Phillip PangChief Medical OfficerBuy5,000Common Stock$5.17-$25,850.00  0.38     [ Average ]114,277$590,812.09  8.79     [Average]Form 4-
2021-06-16Phillip PangChief Medical OfficerSell5,000Common Stock$43.67$218,350.00  0.38     [ Average ]109,277$4,772,126.59  8.40     [Average]Form 4-
2021-06-17Robert J More-Sell11,670Common Stock$43.95$512,896.50  0.90     [ High ]69,369$3,048,767.55  5.33     [Average]Form 4-
2021-06-21Vicki L Sato-Sell11,881Common Stock$46.00$546,526.00  0.91     [ High ]1,645,429$75,689,734.00  126.53   [Very High]Form 4-
2021-06-21Vicki L Sato-Sell3,293Common Stock$46.75$153,947.75  0.25     [ Low ]1,642,136$76,769,858.00  126.28   [Very High]Form 4-
2021-06-22Arch Venture Partners Ix, Llc-Sell435,562Common Stock$0.00$0.00  -11,179,423$0.00  859.69   [Very High]Form 4See footnote
2021-06-22Arch Venture Partners Ix, Llc-Sell564,438Common Stock$0.00$0.00  -14,487,240$0.00  1,114.06 [Very High]Form 4See footnote
2021-06-22Arch Venture Partners Ix, Llc-Buy6,320Common Stock$0.00$0.00  -18,962$0.00  1.46     [Low]Form 4-
2021-06-22Arch Venture Partners Ix, Llc-Buy2,028Common Stock$0.00$0.00  -6,096$0.00  0.47     [Very Low]Form 4-
2021-06-22Robert Nelsen-Sell435,562Common Stock$0.00$0.00  -11,179,423$0.00  859.69   [Very High]Form 4See footnote
2021-06-22Robert Nelsen-Sell564,438Common Stock$0.00$0.00  -14,487,240$0.00  1,114.06 [Very High]Form 4See footnote
2021-06-22Robert Nelsen-Buy11,974Common Stock$0.00$0.00  -35,928$0.00  2.76     [Low]Form 4-
2021-06-23Herbert VirginEVP, Research & CSOBuy8,000Common Stock$1.53-$12,240.00  0.62     [ Average ]99,700$152,541.00  7.67     [Average]Form 4-
2021-06-25Steven J. RiceChief Administrative OfficerBuy3Common Stock$12.76-$38.28  -20,003$255,238.28  1.54     [Low]Form 4-
2021-06-25Steven J. RiceChief Administrative OfficerSell3Common Stock$50.00$150.00  -20,000$1,000,000.00  1.54     [Low]Form 4-
2021-06-29Herbert VirginEVP, Research & CSOBuy1,375Common Stock$1.53-$2,103.75  0.11     [ Low ]101,075$154,644.75  7.77     [Average]Form 4-
2021-06-29Herbert VirginEVP, Research & CSOSell1,375Common Stock$46.63$64,116.25  0.11     [ Low ]99,700$4,649,011.00  7.67     [Average]Form 4-
2021-07-01Robert J More-Sell4,794Common Stock$44.31$212,422.14  0.37     [ Average ]64,575$2,861,318.25  4.97     [Average]Form 4-
2021-07-01Robert J More-Sell5,986Common Stock$45.23$270,746.78  0.46     [ Average ]58,589$2,649,980.47  4.51     [Low]Form 4-
2021-07-01Robert J More-Sell890Common Stock$46.22$41,135.80  0.07     [ Very Low ]57,699$2,666,847.78  4.44     [Low]Form 4-
2021-07-01Arch Venture Partners Ix, Llc-Sell1,742,248Common Stock$0.00$0.00  -9,437,175$0.00  725.71   [Very High]Form 4See footnote
2021-07-01Arch Venture Partners Ix, Llc-Sell2,257,752Common Stock$0.00$0.00  -12,229,488$0.00  940.44   [Very High]Form 4See footnote
2021-07-01Arch Venture Partners Ix, Llc-Buy25,279Common Stock$0.00$0.00  -44,241$0.00  3.40     [Low]Form 4-
2021-07-01Arch Venture Partners Ix, Llc-Buy8,133Common Stock$0.00$0.00  -14,229$0.00  1.09     [Very Low]Form 4-
2021-07-01Robert Nelsen-Sell1,742,248Common Stock$0.00$0.00  -9,437,175$0.00  725.71   [Very High]Form 4See footnote
2021-07-01Robert Nelsen-Sell2,257,752Common Stock$0.00$0.00  -12,229,488$0.00  940.44   [Very High]Form 4See footnote
2021-07-01Robert Nelsen-Buy47,897Common Stock$0.00$0.00  -83,825$0.00  6.45     [Average]Form 4-
2021-07-07Phillip PangChief Medical OfficerBuy5,000Common Stock$5.17-$25,850.00  0.38     [ Average ]114,277$590,812.09  8.79     [Average]Form 4-
2021-07-07Phillip PangChief Medical OfficerSell3,505Common Stock$40.16$140,760.80  0.27     [ Low ]110,772$4,448,603.52  8.52     [Average]Form 4-
2021-07-07Phillip PangChief Medical OfficerSell1,495Common Stock$40.91$61,160.45  0.11     [ Low ]109,277$4,470,522.07  8.40     [Average]Form 4-
2021-07-13Herbert VirginEVP, Research & CSOBuy1,375Common Stock$1.53-$2,103.75  0.11     [ Low ]101,075$154,644.75  7.77     [Average]Form 4-
2021-07-13Herbert VirginEVP, Research & CSOSell1,375Common Stock$36.72$50,490.00  0.11     [ Low ]99,700$3,660,984.00  7.67     [Average]Form 4-
2021-07-15Robert J More-Sell11,670Common Stock$35.56$414,985.20  0.90     [ High ]46,029$1,636,791.24  3.54     [Low]Form 4-
2021-07-19Vicki L Sato-Sell8,811Common Stock$36.74$323,716.14  0.68     [ Average ]1,633,325$60,008,360.50  125.60   [Very High]Form 4-
2021-07-19Vicki L Sato-Sell6,363Common Stock$37.84$240,775.92  0.49     [ Average ]1,626,962$61,564,242.08  125.11   [Very High]Form 4-
2021-07-21Phillip PangChief Medical OfficerBuy4,630Common Stock$1.57-$7,269.10  0.36     [ Average ]113,907$178,833.99  8.76     [Average]Form 4-
2021-07-21Phillip PangChief Medical OfficerSell4,630Common Stock$37.44$173,347.20  0.36     [ Average ]109,277$4,091,330.88  8.40     [Average]Form 4-
2021-07-27Herbert VirginEVP, Research & CSOBuy1,375Common Stock$1.53-$2,103.75  0.11     [ Low ]101,075$154,644.75  7.77     [Average]Form 4-
2021-07-27Herbert VirginEVP, Research & CSOSell1,375Common Stock$36.72$50,490.00  0.11     [ Low ]99,700$3,660,984.00  7.67     [Average]Form 4-
2021-07-01Robert J More-Buy1,671Common Stock$43.53-$72,738.63  0.13     [ Low ]47,700$2,076,381.00  3.67     [Low]Form 4-
2021-07-29Robert J More-Sell9,322Common Stock$36.63$341,464.86  0.72     [ Average ]38,378$1,405,786.14  2.95     [Low]Form 4-
2021-07-29Robert J More-Sell2,348Common Stock$37.58$88,237.84  0.18     [ Low ]36,030$1,354,007.40  2.77     [Low]Form 4-
2021-08-04Phillip PangChief Medical OfficerBuy5,000Common Stock$5.17-$25,850.00  0.38     [ Average ]114,277$590,812.09  8.79     [Average]Form 4-
2021-08-04Phillip PangChief Medical OfficerSell5,000Common Stock$34.92$174,600.00  0.38     [ Average ]109,277$3,815,952.84  8.40     [Average]Form 4-
2021-08-10Herbert VirginEVP, Research & CSOBuy1,375Common Stock$1.53-$2,103.75  0.11     [ Low ]101,075$154,644.75  7.74     [Average]Form 4-
2021-08-10Herbert VirginEVP, Research & CSOSell1,375Common Stock$41.00$56,375.00  0.11     [ Low ]99,700$4,087,700.00  7.63     [Average]Form 4-
2021-08-18Phillip PangChief Medical OfficerBuy5,000Common Stock$1.53-$7,650.00  0.38     [ Average ]114,277$174,843.81  8.75     [Average]Form 4-
2021-08-18Phillip PangChief Medical OfficerSell5,000Common Stock$42.23$211,150.00  0.38     [ Average ]109,277$4,614,767.71  8.37     [Average]Form 4-
2021-08-19Vicki L Sato-Sell6,129Common Stock$44.36$271,882.44  0.47     [ Average ]1,620,833$71,900,151.88  124.10   [Very High]Form 4-
2021-08-19Vicki L Sato-Sell9,045Common Stock$45.52$411,728.40  0.69     [ Average ]1,611,788$73,368,589.76  123.40   [Very High]Form 4-
2021-08-23Herbert VirginEVP, Research & CSOBuy13,750Common Stock$1.53-$21,037.50  1.05     [ High ]113,450$173,578.50  8.69     [Average]Form 4-
2021-08-23Herbert VirginEVP, Research & CSOSell13,750Common Stock$50.00$687,500.00  1.05     [ High ]99,700$4,985,000.00  7.63     [Average]Form 4-
2021-08-23Steven J. RiceChief Administrative OfficerBuy10,000Common Stock$12.76-$127,600.00  0.77     [ High ]30,000$382,800.00  2.30     [Low]Form 4-
2021-08-23Steven J. RiceChief Administrative OfficerSell10,000Common Stock$50.00$500,000.00  0.77     [ High ]20,000$1,000,000.00  1.53     [Low]Form 4-
2021-08-24Herbert VirginEVP, Research & CSOBuy1,375Common Stock$1.53-$2,103.75  0.11     [ Low ]101,075$154,644.75  7.74     [Average]Form 4-
2021-08-24Herbert VirginEVP, Research & CSOSell1,375Common Stock$48.00$66,000.00  0.11     [ Low ]99,700$4,785,600.00  7.63     [Average]Form 4-
2021-08-25Herbert VirginEVP, Research & CSOBuy2,750Common Stock$1.53-$4,207.50  0.21     [ Low ]102,450$156,748.50  7.84     [Average]Form 4-
2021-08-25Herbert VirginEVP, Research & CSOSell2,750Common Stock$50.00$137,500.00  0.21     [ Low ]99,700$4,985,000.00  7.63     [Average]Form 4-
2021-08-30Janet Napolitano-Buy1,435Common Stock$41.64-$59,753.40  0.11     [ Low ]4,809$200,246.76  0.37     [Very Low]Form 4-
2021-08-30Janet Napolitano-Sell1,435Common Stock$51.15$73,400.25  0.11     [ Low ]3,374$172,580.10  0.26     [Very Low]Form 4-
2021-09-01Phillip PangChief Medical OfficerBuy5,000Common Stock$1.53-$7,650.00  0.38     [ Average ]114,277$174,843.81  8.75     [Average]Form 4-
2021-09-01Phillip PangChief Medical OfficerSell1,888Common Stock$48.72$91,983.36  0.14     [ Low ]112,389$5,475,592.08  8.60     [Average]Form 4-
2021-09-01Phillip PangChief Medical OfficerSell1,005Common Stock$49.40$49,647.00  0.08     [ Very Low ]111,384$5,502,369.60  8.53     [Average]Form 4-
2021-09-01Phillip PangChief Medical OfficerSell2,107Common Stock$50.43$106,256.01  0.16     [ Low ]109,277$5,510,839.11  8.37     [Average]Form 4-
2021-09-07Herbert VirginEVP, Research & CSOBuy4,125Common Stock$1.53-$6,311.25  0.32     [ Average ]103,825$158,852.25  7.95     [Average]Form 4-
2021-09-07Herbert VirginEVP, Research & CSOSell1,375Common Stock$49.00$67,375.00  0.11     [ Low ]102,450$5,020,050.00  7.84     [Average]Form 4-
2021-09-07Herbert VirginEVP, Research & CSOSell2,750Common Stock$50.00$137,500.00  0.21     [ Low ]99,700$4,985,000.00  7.63     [Average]Form 4-
2021-09-15Phillip PangChief Medical OfficerSell4,280Common Stock$49.58$212,202.40  0.33     [ Average ]104,997$5,205,751.26  8.04     [Average]Form 4-
2021-09-15Phillip PangChief Medical OfficerSell720Common Stock$50.36$36,259.20  0.06     [ Very Low ]104,277$5,251,389.72  7.98     [Average]Form 4-
2021-09-17Vicki L Sato-Sell11,775Common Stock$52.31$615,950.25  0.90     [ High ]1,600,013$83,696,680.03  122.50   [Very High]Form 4-
2021-09-17Vicki L Sato-Sell3,399Common Stock$53.06$180,350.94  0.26     [ Low ]1,596,614$84,716,338.84  122.24   [Very High]Form 4-
2021-09-21Herbert VirginEVP, Research & CSOBuy4,125Common Stock$1.53-$6,311.25  0.32     [ Average ]103,825$158,852.25  7.95     [Average]Form 4-
2021-09-21Herbert VirginEVP, Research & CSOSell4,125Common Stock$50.00$206,250.00  0.32     [ Average ]99,700$4,985,000.00  7.63     [Average]Form 4-
2021-09-22Herbert VirginEVP, Research & CSOBuy8,000Common Stock$1.53-$12,240.00  0.61     [ Average ]107,700$164,781.00  8.25     [Average]Form 4-
2021-09-27Phillip PangChief Medical OfficerBuy5,000Common Stock$0.85-$4,250.00  0.38     [ Average ]109,277$92,885.45  8.37     [Average]Form 4-
2021-10-05Herbert VirginEVP, Research & CSOBuy1,375Common Stock$1.53-$2,103.75  0.11     [ Low ]109,075$166,884.75  8.35     [Average]Form 4-
2021-10-05Herbert VirginEVP, Research & CSOSell1,375Common Stock$33.75$46,406.25  0.11     [ Low ]107,700$3,634,875.00  8.25     [Average]Form 4-
2021-10-06Phillip PangChief Medical OfficerSell5,000Common Stock$34.56$172,800.00  0.38     [ Average ]104,277$3,603,813.12  7.98     [Average]Form 4-
2021-10-19Vicki L Sato-Sell6,671Common Stock$39.12$260,969.52  0.51     [ Average ]1,589,943$62,198,570.16  121.73   [Very High]Form 4-
2021-10-19Vicki L Sato-Sell8,503Common Stock$39.91$339,354.73  0.65     [ Average ]1,581,440$63,115,270.40  121.08   [Very High]Form 4-
2021-10-19Herbert VirginEVP, Research & CSOBuy1,375Common Stock$1.53-$2,103.75  0.11     [ Low ]109,075$166,884.75  8.35     [Average]Form 4-
2021-10-19Herbert VirginEVP, Research & CSOSell1,375Common Stock$38.87$53,446.25  0.11     [ Low ]107,700$4,186,299.00  8.25     [Average]Form 4-
2021-10-20Phillip PangChief Medical OfficerSell4,000Common Stock$39.65$158,600.00  0.31     [ Average ]100,277$3,975,983.05  7.68     [Average]Form 4-
2021-11-02Herbert VirginEVP, Research & CSOBuy1,375Common Stock$1.53-$2,103.75  0.11     [ Low ]109,075$166,884.75  8.35     [Average]Form 4-
2021-11-02Herbert VirginEVP, Research & CSOSell1,375Common Stock$36.94$50,792.50  0.11     [ Low ]107,700$3,978,438.00  8.25     [Average]Form 4-
2021-11-03Phillip PangChief Medical OfficerBuy5,000Common Stock$5.17-$25,850.00  0.38     [ Average ]105,277$544,282.09  8.06     [Average]Form 4-
2021-11-03Phillip PangChief Medical OfficerSell5,000Common Stock$36.47$182,350.00  0.38     [ Average ]100,277$3,657,102.19  7.68     [Average]Form 4-
2021-11-16Herbert VirginEVP, Research & CSOBuy1,375Common Stock$1.53-$2,103.75  0.11     [ Low ]109,075$166,884.75  8.33     [Average]Form 4-
2021-11-16Herbert VirginEVP, Research & CSOSell1,375Common Stock$32.67$44,921.25  0.11     [ Low ]107,700$3,518,559.00  8.23     [Average]Form 4-
2021-11-17Phillip PangChief Medical OfficerBuy5,000Common Stock$5.17-$25,850.00  0.38     [ Average ]105,277$544,282.09  8.04     [Average]Form 4-
2021-11-17Phillip PangChief Medical OfficerSell4,535Common Stock$35.75$162,126.25  0.35     [ Average ]100,742$3,601,526.50  7.70     [Average]Form 4-
2021-11-17Phillip PangChief Medical OfficerSell465Common Stock$36.80$17,112.00  0.04     [ Very Low ]100,277$3,690,193.60  7.66     [Average]Form 4-
2021-11-22Arch Venture Partners Ix, Llc-Sell217,781Common Stock$0.00$0.00  -9,219,394$0.00  704.42   [Very High]Form 4See footnote
2021-11-22Arch Venture Partners Ix, Llc-Sell282,219Common Stock$0.00$0.00  -11,947,269$0.00  912.84   [Very High]Form 4See footnote
2021-11-22Arch Venture Partners Ix, Llc-Buy13,057Common Stock$0.00$0.00  -57,298$0.00  4.38     [Low]Form 4-
2021-11-22Arch Venture Partners Ix, Llc-Buy4,428Common Stock$0.00$0.00  -18,657$0.00  1.43     [Low]Form 4-
2021-11-22Robert Nelsen-Sell217,781Common Stock$0.00$0.00  -9,219,394$0.00  704.42   [Very High]Form 4See footnote
2021-11-22Robert Nelsen-Sell282,219Common Stock$0.00$0.00  -11,947,269$0.00  912.84   [Very High]Form 4See footnote
2021-11-22Robert Nelsen-Buy29,153Common Stock$0.00$0.00  -112,978$0.00  8.63     [Average]Form 4-
2021-11-26Vicki L Sato-Sell15,174Common Stock$36.80$558,403.20  1.16     [ High ]1,566,266$57,638,588.80  119.67   [Very High]Form 4-
2021-11-29Arch Venture Partners Ix, Llc-Sell217,781Common Stock$0.00$0.00  -9,001,613$0.00  687.78   [Very High]Form 4See footnote
2021-11-29Arch Venture Partners Ix, Llc-Sell282,219Common Stock$0.00$0.00  -11,665,050$0.00  891.28   [Very High]Form 4See footnote
2021-11-29Arch Venture Partners Ix, Llc-Buy13,057Common Stock$0.00$0.00  -70,355$0.00  5.38     [Average]Form 4-
2021-11-29Arch Venture Partners Ix, Llc-Buy4,428Common Stock$0.00$0.00  -23,085$0.00  1.76     [Low]Form 4-
2021-11-29Robert Nelsen-Sell217,781Common Stock$0.00$0.00  -9,001,613$0.00  687.78   [Very High]Form 4See footnote
2021-11-29Robert Nelsen-Sell282,219Common Stock$0.00$0.00  -11,665,050$0.00  891.28   [Very High]Form 4See footnote
2021-11-29Robert Nelsen-Buy29,153Common Stock$0.00$0.00  -142,131$0.00  10.86    [Average]Form 4-
2021-11-29Ann M. HanlyChief Technology OfficerBuy12Common Stock$43.39-$499.85  -12$499.85  -Form 4See footnote
2021-11-30Janet Napolitano-Buy1,435Common Stock$41.64-$59,753.40  0.11     [ Low ]4,809$200,246.76  0.37     [Very Low]Form 4-
2021-11-30Janet Napolitano-Sell1,435Common Stock$46.25$66,368.75  0.11     [ Low ]3,374$156,047.50  0.26     [Very Low]Form 4-
2021-11-30Steven J. RiceChief Administrative OfficerBuy10,000Common Stock$12.76-$127,600.00  0.76     [ Average ]30,600$390,456.00  2.34     [Low]Form 4-
2021-11-30Steven J. RiceChief Administrative OfficerSell10,000Common Stock$50.00$500,000.00  0.76     [ Average ]20,600$1,030,000.00  1.57     [Low]Form 4-
2021-11-30Herbert VirginEVP, Research & CSOBuy15,125Common Stock$1.53-$23,141.25  1.16     [ High ]122,825$187,922.25  9.38     [Average]Form 4-
2021-11-30Herbert VirginEVP, Research & CSOSell1,375Common Stock$45.60$62,700.00  0.11     [ Low ]121,450$5,538,120.00  9.28     [Average]Form 4-
2021-11-30Herbert VirginEVP, Research & CSOSell13,750Common Stock$50.00$687,500.00  1.05     [ High ]107,700$5,385,000.00  8.23     [Average]Form 4-
2021-12-01Phillip PangChief Medical OfficerSell950Common Stock$41.82$39,729.00  0.07     [ Very Low ]99,327$4,153,855.14  7.59     [Average]Form 4-
2021-12-01Phillip PangChief Medical OfficerSell4,409Common Stock$43.46$191,615.14  0.34     [ Average ]94,918$4,125,136.28  7.25     [Average]Form 4-
2021-12-01Phillip PangChief Medical OfficerSell2,050Common Stock$44.10$90,405.00  0.16     [ Low ]92,868$4,095,478.80  7.10     [Average]Form 4-
2021-12-01Phillip PangChief Medical OfficerSell91Common Stock$44.97$4,092.27  -92,777$4,172,181.69  7.09     [Average]Form 4-